BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

275 related articles for article (PubMed ID: 22158614)

  • 1. E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress.
    Otero M; Plumb DA; Tsuchimochi K; Dragomir CL; Hashimoto K; Peng H; Olivotto E; Bevilacqua M; Tan L; Yang Z; Zhan Y; Oettgen P; Li Y; Marcu KB; Goldring MB
    J Biol Chem; 2012 Jan; 287(5):3559-72. PubMed ID: 22158614
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ELF3 modulates type II collagen gene (COL2A1) transcription in chondrocytes by inhibiting SOX9-CBP/p300-driven histone acetyltransferase activity.
    Otero M; Peng H; Hachem KE; Culley KL; Wondimu EB; Quinn J; Asahara H; Tsuchimochi K; Hashimoto K; Goldring MB
    Connect Tissue Res; 2017 Jan; 58(1):15-26. PubMed ID: 27310669
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Elf3 Contributes to Cartilage Degradation in vivo in a Surgical Model of Post-Traumatic Osteoarthritis.
    Wondimu EB; Culley KL; Quinn J; Chang J; Dragomir CL; Plumb DA; Goldring MB; Otero M
    Sci Rep; 2018 Apr; 8(1):6438. PubMed ID: 29691435
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1β (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites.
    Hashimoto K; Otero M; Imagawa K; de Andrés MC; Coico JM; Roach HI; Oreffo ROC; Marcu KB; Goldring MB
    J Biol Chem; 2013 Apr; 288(14):10061-10072. PubMed ID: 23417678
    [TBL] [Abstract][Full Text] [Related]  

  • 5. E74-Like Factor (ELF3) and Leptin, a Novel Loop Between Obesity and Inflammation Perpetuating a Pro-Catabolic State in Cartilage.
    Conde J; Otero M; Scotece M; Abella V; Gómez R; López V; Pino J; Mera A; Goldring MB; Gualillo O
    Cell Physiol Biochem; 2018; 45(6):2401-2410. PubMed ID: 29550824
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcriptional activation of human MMP-13 gene expression by c-Maf in osteoarthritic chondrocyte.
    Li T; Xiao J; Wu Z; Qiu G; Ding Y
    Connect Tissue Res; 2010; 51(1):48-54. PubMed ID: 20067416
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytokine-induced MMP13 Expression in Human Chondrocytes Is Dependent on Activating Transcription Factor 3 (ATF3) Regulation.
    Chan CM; Macdonald CD; Litherland GJ; Wilkinson DJ; Skelton A; Europe-Finner GN; Rowan AD
    J Biol Chem; 2017 Feb; 292(5):1625-1636. PubMed ID: 27956552
    [TBL] [Abstract][Full Text] [Related]  

  • 8. LEF1-mediated MMP13 gene expression is repressed by SIRT1 in human chondrocytes.
    Elayyan J; Lee EJ; Gabay O; Smith CA; Qiq O; Reich E; Mobasheri A; Henrotin Y; Kimber SJ; Dvir-Ginzberg M
    FASEB J; 2017 Jul; 31(7):3116-3125. PubMed ID: 28389425
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ESE-1 is a potent repressor of type II collagen gene (COL2A1) transcription in human chondrocytes.
    Peng H; Tan L; Osaki M; Zhan Y; Ijiri K; Tsuchimochi K; Otero M; Wang H; Choy BK; Grall FT; Gu X; Libermann TA; Oettgen P; Goldring MB
    J Cell Physiol; 2008 May; 215(2):562-73. PubMed ID: 18044710
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Brief report: stress-inducible nuclear protein 1 regulates matrix metalloproteinase 13 expression in human articular chondrocytes.
    Yammani RR; Loeser RF
    Arthritis Rheumatol; 2014 May; 66(5):1266-71. PubMed ID: 24497499
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development.
    Niebler S; Schubert T; Hunziker EB; Bosserhoff AK
    Arthritis Res Ther; 2015 May; 17(1):119. PubMed ID: 25964075
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of interleukin 1-induced matrix metalloproteinase 13 expression in human chondrocytes by interferon gamma.
    Ahmad R; Qureshi HY; El Mabrouk M; Sylvester J; Ahmad M; Zafarullah M
    Ann Rheum Dis; 2007 Jun; 66(6):782-9. PubMed ID: 17179173
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insulin-Like Growth Factor II (IGF-II) Inhibits IL-1β-Induced Cartilage Matrix Loss and Promotes Cartilage Integrity in Experimental Osteoarthritis.
    Uchimura T; Foote AT; Smith EL; Matzkin EG; Zeng L
    J Cell Biochem; 2015 Dec; 116(12):2858-69. PubMed ID: 26015264
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanical and IL-1β Responsive miR-365 Contributes to Osteoarthritis Development by Targeting Histone Deacetylase 4.
    Yang X; Guan Y; Tian S; Wang Y; Sun K; Chen Q
    Int J Mol Sci; 2016 Mar; 17(4):436. PubMed ID: 27023516
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Deletion of the transforming growth factor β receptor type II gene in articular chondrocytes leads to a progressive osteoarthritis-like phenotype in mice.
    Shen J; Li J; Wang B; Jin H; Wang M; Zhang Y; Yang Y; Im HJ; O'Keefe R; Chen D
    Arthritis Rheum; 2013 Dec; 65(12):3107-19. PubMed ID: 23982761
    [TBL] [Abstract][Full Text] [Related]  

  • 16. E74-like factor 3 and nuclear factor-κB regulate lipocalin-2 expression in chondrocytes.
    Conde J; Otero M; Scotece M; Abella V; López V; Pino J; Gómez R; Lago F; Goldring MB; Gualillo O
    J Physiol; 2016 Nov; 594(21):6133-6146. PubMed ID: 27222093
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The IL-1β/AP-1/miR-30a/ADAMTS-5 axis regulates cartilage matrix degradation in human osteoarthritis.
    Ji Q; Xu X; Zhang Q; Kang L; Xu Y; Zhang K; Li L; Liang Y; Hong T; Ye Q; Wang Y
    J Mol Med (Berl); 2016 Jul; 94(7):771-85. PubMed ID: 27067395
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes.
    Takahashi A; de Andrés MC; Hashimoto K; Itoi E; Otero M; Goldring MB; Oreffo ROC
    Sci Rep; 2017 Aug; 7(1):7771. PubMed ID: 28798419
    [TBL] [Abstract][Full Text] [Related]  

  • 19. cAMP response element-binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis.
    Bui C; Barter MJ; Scott JL; Xu Y; Galler M; Reynard LN; Rowan AD; Young DA
    FASEB J; 2012 Jul; 26(7):3000-11. PubMed ID: 22505473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes.
    Burguera EF; Vela-Anero A; Magalhães J; Meijide-Faílde R; Blanco FJ
    Osteoarthritis Cartilage; 2014 Jul; 22(7):1026-35. PubMed ID: 24831018
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.