149 related articles for article (PubMed ID: 22163192)
1. Neoamphimedine circumvents metnase-enhanced DNA topoisomerase IIα activity through ATP-competitive inhibition.
Ponder J; Yoo BH; Abraham AD; Li Q; Ashley AK; Amerin CL; Zhou Q; Reid BG; Reigan P; Hromas R; Nickoloff JA; LaBarbera DV
Mar Drugs; 2011; 9(11):2397-2408. PubMed ID: 22163192
[TBL] [Abstract][Full Text] [Related]
2. The SET and transposase domain protein Metnase enhances chromosome decatenation: regulation by automethylation.
Williamson EA; Rasila KK; Corwin LK; Wray J; Beck BD; Severns V; Mobarak C; Lee SH; Nickoloff JA; Hromas R
Nucleic Acids Res; 2008 Oct; 36(18):5822-31. PubMed ID: 18790802
[TBL] [Abstract][Full Text] [Related]
3. Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells.
Wray J; Williamson EA; Royce M; Shaheen M; Beck BD; Lee SH; Nickoloff JA; Hromas R
PLoS One; 2009; 4(4):e5323. PubMed ID: 19390626
[TBL] [Abstract][Full Text] [Related]
4. Metnase mediates chromosome decatenation in acute leukemia cells.
Wray J; Williamson EA; Sheema S; Lee SH; Libby E; Willman CL; Nickoloff JA; Hromas R
Blood; 2009 Aug; 114(9):1852-8. PubMed ID: 19458360
[TBL] [Abstract][Full Text] [Related]
5. Metnase promotes restart and repair of stalled and collapsed replication forks.
De Haro LP; Wray J; Williamson EA; Durant ST; Corwin L; Gentry AC; Osheroff N; Lee SH; Hromas R; Nickoloff JA
Nucleic Acids Res; 2010 Sep; 38(17):5681-91. PubMed ID: 20457750
[TBL] [Abstract][Full Text] [Related]
6. An improved high yield total synthesis and cytotoxicity study of the marine alkaloid neoamphimedine: an ATP-competitive inhibitor of topoisomerase IIα and potent anticancer agent.
Li L; Abraham AD; Zhou Q; Ali H; O'Brien JV; Hamill BD; Arcaroli JJ; Messersmith WA; LaBarbera DV
Mar Drugs; 2014 Sep; 12(9):4833-50. PubMed ID: 25244109
[TBL] [Abstract][Full Text] [Related]
7. Geminin overexpression prevents the completion of topoisomerase IIα chromosome decatenation, leading to aneuploidy in human mammary epithelial cells.
Gardner L; Malik R; Shimizu Y; Mullins N; ElShamy WM
Breast Cancer Res; 2011 May; 13(3):R53. PubMed ID: 21595939
[TBL] [Abstract][Full Text] [Related]
8. The anti-neoplastic and novel topoisomerase II-mediated cytotoxicity of neoamphimedine, a marine pyridoacridine.
Marshall KM; Matsumoto SS; Holden JA; Concepción GP; Tasdemir D; Ireland CM; Barrows LR
Biochem Pharmacol; 2003 Aug; 66(3):447-58. PubMed ID: 12907244
[TBL] [Abstract][Full Text] [Related]
9. Topoisomerase IIα mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.
Zhou Q; Abraham AD; Li L; Babalmorad A; Bagby S; Arcaroli JJ; Hansen RJ; Valeriote FA; Gustafson DL; Schaack J; Messersmith WA; LaBarbera DV
Oncogene; 2016 Sep; 35(38):4990-9. PubMed ID: 26947016
[TBL] [Abstract][Full Text] [Related]
10. Prognostic potential of topoisomerase IIα and HER2 in a retrospective analysis of early advanced breast cancer patients treated with adjuvant anthracycline chemotherapy.
Biesaga B; Niemiec J; Ziobro M; Wysocka J; Kruczak A
Breast; 2011 Aug; 20(4):338-50. PubMed ID: 21507646
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human topoisomerase IIα catalytic inhibitor.
Ahmad P; Woo H; Jun KY; Kadi AA; Abdel-Aziz HA; Kwon Y; Rahman AF
Bioorg Med Chem; 2016 Apr; 24(8):1898-908. PubMed ID: 26988802
[TBL] [Abstract][Full Text] [Related]
12. PIASy-dependent SUMOylation regulates DNA topoisomerase IIalpha activity.
Ryu H; Furuta M; Kirkpatrick D; Gygi SP; Azuma Y
J Cell Biol; 2010 Nov; 191(4):783-94. PubMed ID: 21079245
[TBL] [Abstract][Full Text] [Related]
13. Novel trifluoromethylated 9-amino-3,4-dihydroacridin-1(2H)-ones act as covalent poisons of human topoisomerase IIα.
Infante Lara L; Sledge A; Laradji A; Okoro CO; Osheroff N
Bioorg Med Chem Lett; 2017 Feb; 27(3):586-589. PubMed ID: 27998679
[TBL] [Abstract][Full Text] [Related]
14. The p53 tumor suppressor stimulates the catalytic activity of human topoisomerase IIalpha by enhancing the rate of ATP hydrolysis.
Kwon Y; Shin BS; Chung IK
J Biol Chem; 2000 Jun; 275(24):18503-10. PubMed ID: 10764786
[TBL] [Abstract][Full Text] [Related]
15. Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIα catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells.
Islam MS; Park S; Song C; Kadi AA; Kwon Y; Rahman AF
Eur J Med Chem; 2017 Jan; 125():49-67. PubMed ID: 27654394
[TBL] [Abstract][Full Text] [Related]
16. Therapeutic potential and molecular mechanism of a novel sulfonamide anticancer drug, indisulam (E7070) in combination with CPT-11 for cancer treatment.
Ozawa Y; Kusano K; Owa T; Yokoi A; Asada M; Yoshimatsu K
Cancer Chemother Pharmacol; 2012 May; 69(5):1353-62. PubMed ID: 22349812
[TBL] [Abstract][Full Text] [Related]
17. Substituents on etoposide that interact with human topoisomerase IIalpha in the binary enzyme-drug complex: contributions to etoposide binding and activity.
Bender RP; Jablonksy MJ; Shadid M; Romaine I; Dunlap N; Anklin C; Graves DE; Osheroff N
Biochemistry; 2008 Apr; 47(15):4501-9. PubMed ID: 18355043
[TBL] [Abstract][Full Text] [Related]
18. Topoisomerase IIalpha maintains genomic stability through decatenation G(2) checkpoint signaling.
Bower JJ; Karaca GF; Zhou Y; Simpson DA; Cordeiro-Stone M; Kaufmann WK
Oncogene; 2010 Aug; 29(34):4787-99. PubMed ID: 20562910
[TBL] [Abstract][Full Text] [Related]
19. A high-throughput fluorescence anisotropy-based assay for human topoisomerase II β-catalyzed ATP-dependent supercoiled DNA relaxation.
Shapiro AB; Austin CA
Anal Biochem; 2014 Mar; 448():23-9. PubMed ID: 24309019
[TBL] [Abstract][Full Text] [Related]
20. 3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.
Park SE; Chang IH; Jun KY; Lee E; Lee ES; Na Y; Kwon Y
Eur J Med Chem; 2013 Nov; 69():139-45. PubMed ID: 24013413
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
