These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 22164302)

  • 1. Neighborhood properties are important determinants of temperature sensitive mutations.
    Lockwood S; Krishnamoorthy B; Ye P
    PLoS One; 2011; 6(12):e28507. PubMed ID: 22164302
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isolation of Fission Yeast Condensin Temperature-Sensitive Mutants with Single Amino Acid Substitutions Targeted to Hinge Domain.
    Xu X; Yanagida M
    G3 (Bethesda); 2019 May; 9(5):1777-1783. PubMed ID: 30914423
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rational design of temperature-sensitive alleles using computational structure prediction.
    Poultney CS; Butterfoss GL; Gutwein MR; Drew K; Gresham D; Gunsalus KC; Shasha DE; Bonneau R
    PLoS One; 2011; 6(9):e23947. PubMed ID: 21912654
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular Determinants of Temperature-Sensitive Phenotypes.
    Tripathi A; Swaroop S; Varadarajan R
    Biochemistry; 2019 Apr; 58(13):1738-1750. PubMed ID: 30843689
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural correlates of the temperature sensitive phenotype derived from saturation mutagenesis studies of CcdB.
    Bajaj K; Dewan PC; Chakrabarti P; Goswami D; Barua B; Baliga C; Varadarajan R
    Biochemistry; 2008 Dec; 47(49):12964-73. PubMed ID: 19006334
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design of temperature-sensitive mutants solely from amino acid sequence.
    Chakshusmathi G; Mondal K; Lakshmi GS; Singh G; Roy A; Ch RB; Madhusudhanan S; Varadarajan R
    Proc Natl Acad Sci U S A; 2004 May; 101(21):7925-30. PubMed ID: 15148363
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Statistical geometry based prediction of nonsynonymous SNP functional effects using random forest and neuro-fuzzy classifiers.
    Barenboim M; Masso M; Vaisman II; Jamison DC
    Proteins; 2008 Jun; 71(4):1930-9. PubMed ID: 18186470
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and utility of temperature-sensitive Gal4 mutants for conditional gene expression in Drosophila.
    Mondal K; VijayRaghavan K; Varadarajan R
    Fly (Austin); 2007; 1(5):282-6. PubMed ID: 18836309
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TSpred: a web server for the rational design of temperature-sensitive mutants.
    Tan KP; Khare S; Varadarajan R; Madhusudhan MS
    Nucleic Acids Res; 2014 Jul; 42(Web Server issue):W277-84. PubMed ID: 24782523
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Prediction of deleterious functional effects of amino acid mutations using a library of structure-based function descriptors.
    Herrgard S; Cammer SA; Hoffman BT; Knutson S; Gallina M; Speir JA; Fetrow JS; Baxter SM
    Proteins; 2003 Dec; 53(4):806-16. PubMed ID: 14635123
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A procedure for the prediction of temperature-sensitive mutants of a globular protein based solely on the amino acid sequence.
    Varadarajan R; Nagarajaram HA; Ramakrishnan C
    Proc Natl Acad Sci U S A; 1996 Nov; 93(24):13908-13. PubMed ID: 8943034
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Accurate prediction of stability changes in protein mutants by combining machine learning with structure based computational mutagenesis.
    Masso M; Vaisman II
    Bioinformatics; 2008 Sep; 24(18):2002-9. PubMed ID: 18632749
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Assessing the performance of computational predictors for estimating protein stability changes upon missense mutations.
    Iqbal S; Li F; Akutsu T; Ascher DB; Webb GI; Song J
    Brief Bioinform; 2021 Nov; 22(6):. PubMed ID: 34058752
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Temperature-sensitive mutations made easy: generating conditional mutations by using temperature-sensitive inteins that function within different temperature ranges.
    Tan G; Chen M; Foote C; Tan C
    Genetics; 2009 Sep; 183(1):13-22. PubMed ID: 19596904
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Machine learning algorithms for predicting protein folding rates and stability of mutant proteins: comparison with statistical methods.
    Gromiha MM; Huang LT
    Curr Protein Pept Sci; 2011 Sep; 12(6):490-502. PubMed ID: 21787301
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An integrative computational framework based on a two-step random forest algorithm improves prediction of zinc-binding sites in proteins.
    Zheng C; Wang M; Takemoto K; Akutsu T; Zhang Z; Song J
    PLoS One; 2012; 7(11):e49716. PubMed ID: 23166753
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequential addition of temperature-sensitive missense mutations into the PB2 gene of influenza A transfectant viruses can effect an increase in temperature sensitivity and attenuation and permits the rational design of a genetically engineered live influenza A virus vaccine.
    Subbarao EK; Park EJ; Lawson CM; Chen AY; Murphy BR
    J Virol; 1995 Oct; 69(10):5969-77. PubMed ID: 7666501
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation.
    Da Costa B; Sausset A; Munier S; Ghounaris A; Naffakh N; Le Goffic R; Delmas B
    J Virol; 2015 Jun; 89(12):6376-90. PubMed ID: 25855727
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The two amino acid substitutions in the L protein of cpts530/1009, a live-attenuated respiratory syncytial virus candidate vaccine, are independent temperature-sensitive and attenuation mutations.
    Juhasz K; Whitehead SS; Boulanger CA; Firestone CY; Collins PL; Murphy BR
    Vaccine; 1999 Mar; 17(11-12):1416-24. PubMed ID: 10195777
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Feature-based multiple models improve classification of mutation-induced stability changes.
    Folkman L; Stantic B; Sattar A
    BMC Genomics; 2014; 15 Suppl 4(Suppl 4):S6. PubMed ID: 25057118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.