BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 22170213)

  • 1. Role of K63-linked polyubiquitination in NF-κB signalling: which ligase catalyzes and what molecule is targeted?
    Hayakawa M
    J Biochem; 2012 Feb; 151(2):115-8. PubMed ID: 22170213
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of the IκB kinase complex by HTLV-1 Tax requires cytosolic factors involved in Tax-induced polyubiquitination.
    Shibata Y; Tanaka Y; Gohda J; Inoue J
    J Biochem; 2011 Dec; 150(6):679-86. PubMed ID: 21862596
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation.
    Choi YB; Harhaj EW
    PLoS Pathog; 2014 Oct; 10(10):e1004458. PubMed ID: 25340740
    [TBL] [Abstract][Full Text] [Related]  

  • 4. HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation.
    Ho YK; Zhi H; Bowlin T; Dorjbal B; Philip S; Zahoor MA; Shih HM; Semmes OJ; Schaefer B; Glover JN; Giam CZ
    PLoS Pathog; 2015 Aug; 11(8):e1005102. PubMed ID: 26285145
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.
    Shibata Y; Tokunaga F; Goto E; Komatsu G; Gohda J; Saeki Y; Tanaka K; Takahashi H; Sawasaki T; Inoue S; Oshiumi H; Seya T; Nakano H; Tanaka Y; Iwai K; Inoue JI
    PLoS Pathog; 2017 Jan; 13(1):e1006162. PubMed ID: 28103322
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ubiquitylated Tax targets and binds the IKK signalosome at the centrosome.
    Kfoury Y; Nasr R; Favre-Bonvin A; El-Sabban M; Renault N; Giron ML; Setterblad N; Hajj HE; Chiari E; Mikati AG; Hermine O; Saib A; de Thé H; Pique C; Bazarbachi A
    Oncogene; 2008 Mar; 27(12):1665-76. PubMed ID: 17891179
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin Chains.
    Wang C; Long W; Peng C; Hu L; Zhang Q; Wu A; Zhang X; Duan X; Wong CC; Tanaka Y; Xia Z
    PLoS Pathog; 2016 Apr; 12(4):e1005584. PubMed ID: 27082114
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation.
    Mohanty S; Han T; Choi YB; Lavorgna A; Zhang J; Harhaj EW
    PLoS Pathog; 2020 Dec; 16(12):e1008504. PubMed ID: 33362245
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase.
    Harhaj NS; Sun SC; Harhaj EW
    J Biol Chem; 2007 Feb; 282(6):4185-92. PubMed ID: 17145747
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK.
    Wu X; Sun SC
    EMBO Rep; 2007 May; 8(5):510-5. PubMed ID: 17363973
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation.
    Bonnet A; Randrianarison-Huetz V; Nzounza P; Nedelec M; Chazal M; Waast L; Pene S; Bazarbachi A; Mahieux R; Bénit L; Pique C
    Retrovirology; 2012 Sep; 9():77. PubMed ID: 23009398
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-κB by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein.
    Forlani G; Abdallah R; Accolla RS; Tosi G
    J Virol; 2016 Jan; 90(7):3708-21. PubMed ID: 26792751
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.
    Lavorgna A; Harhaj EW
    Viruses; 2014 Oct; 6(10):3925-43. PubMed ID: 25341660
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein.
    Lamsoul I; Lodewick J; Lebrun S; Brasseur R; Burny A; Gaynor RB; Bex F
    Mol Cell Biol; 2005 Dec; 25(23):10391-406. PubMed ID: 16287853
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HTLV-1 Tax-induced NFkappaB activation is independent of Lys-63-linked-type polyubiquitination.
    Gohda J; Irisawa M; Tanaka Y; Sato S; Ohtani K; Fujisawa J; Inoue J
    Biochem Biophys Res Commun; 2007 May; 357(1):225-30. PubMed ID: 17418100
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The autophagy molecule Beclin 1 maintains persistent activity of NF-κB and Stat3 in HTLV-1-transformed T lymphocytes.
    Chen L; Liu D; Zhang Y; Zhang H; Cheng H
    Biochem Biophys Res Commun; 2015 Oct; 465(4):739-45. PubMed ID: 26319552
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of I-kappaB kinase by the HTLV type 1 Tax protein: mechanistic insights into the adaptor function of IKKgamma.
    Sun SC; Harhaj EW; Xiao G; Good L
    AIDS Res Hum Retroviruses; 2000 Nov; 16(16):1591-6. PubMed ID: 11080796
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected].
    Wu CJ; Conze DB; Li T; Srinivasula SM; Ashwell JD
    Nat Cell Biol; 2006 Apr; 8(4):398-406. PubMed ID: 16547522
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation.
    Shembade N; Harhaj NS; Yamamoto M; Akira S; Harhaj EW
    J Virol; 2007 Dec; 81(24):13735-42. PubMed ID: 17942533
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases.
    Sun SC; Ballard DW
    Oncogene; 1999 Nov; 18(49):6948-58. PubMed ID: 10602469
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.