These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 22172011)

  • 21. Calculating proton uptake/release and binding free energy taking into account ionization and conformation changes induced by protein-inhibitor association: application to plasmepsin, cathepsin D and endothiapepsin-pepstatin complexes.
    Alexov E
    Proteins; 2004 Aug; 56(3):572-84. PubMed ID: 15229889
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided design.
    Kontopidis G; Andrews MJ; McInnes C; Plater A; Innes L; Renachowski S; Cowan A; Fischer PM
    ChemMedChem; 2009 Jul; 4(7):1120-8. PubMed ID: 19472269
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Molecular dynamics simulations and statistical coupling analysis reveal functional coevolution network of oncogenic mutations in the CDKN2A-CDK6 complex.
    Wang J; Zhao Y; Wang Y; Huang J
    FEBS Lett; 2013 Jan; 587(2):136-41. PubMed ID: 23178718
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Preferences for phosphorylation sites in the retinoblastoma protein of D-type cyclin-dependent kinases, Cdk4 and Cdk6, in vitro.
    Takaki T; Fukasawa K; Suzuki-Takahashi I; Semba K; Kitagawa M; Taya Y; Hirai H
    J Biochem; 2005 Mar; 137(3):381-6. PubMed ID: 15809340
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Unveiling Conformational States of CDK6 Caused by Binding of Vcyclin Protein and Inhibitor by Combining Gaussian Accelerated Molecular Dynamics and Deep Learning.
    Zhao L; Wang J; Yang W; Zhao K; Sun Q; Chen J
    Molecules; 2024 Jun; 29(11):. PubMed ID: 38893554
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Ectopic expression of Cdk6 circumvents transforming growth factor-beta mediated growth inhibition.
    Zhang F; Taipale M; Heiskanen A; Laiho M
    Oncogene; 2001 Sep; 20(41):5888-96. PubMed ID: 11593394
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Extra precision docking, free energy calculation and molecular dynamics simulation studies of CDK2 inhibitors.
    Tripathi SK; Muttineni R; Singh SK
    J Theor Biol; 2013 Oct; 334():87-100. PubMed ID: 23727278
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Extrapolating the effect of deleterious nsSNPs in the binding adaptability of flavopiridol with CDK7 protein: a molecular dynamics approach.
    George Priya Doss C; Nagasundaram N; Chakraborty C; Chen L; Zhu H
    Hum Genomics; 2013 Apr; 7(1):10. PubMed ID: 23561625
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Controlling cell proliferation by targeting cyclin-dependent kinase 6 using drug repurposing approach.
    Madhana Priya N; Balasundaram A; Sidharth Kumar N; Udhaya Kumar S; Thirumal Kumar D; Magesh R; Zayed H; George Priya Doss C
    Adv Protein Chem Struct Biol; 2023; 135():97-124. PubMed ID: 37061342
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibition of chrysin on xanthine oxidase activity and its inhibition mechanism.
    Lin S; Zhang G; Liao Y; Pan J
    Int J Biol Macromol; 2015 Nov; 81():274-82. PubMed ID: 26275460
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Development of novel HER2 inhibitors against gastric cancer derived from flavonoid source of
    Babu TM; Rammohan A; Baki VB; Devi S; Gunasekar D; Rajendra W
    Drug Des Devel Ther; 2016; 10():3611-3632. PubMed ID: 27853354
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Predicting the impact of single-nucleotide polymorphisms in CDK2-flavopiridol complex by molecular dynamics analysis.
    Nagasundaram N; Doss CG
    Cell Biochem Biophys; 2013 Jul; 66(3):681-95. PubMed ID: 23300027
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Molecular docking and dynamics simulation study of flavonoids as BET bromodomain inhibitors.
    Raj U; Kumar H; Varadwaj PK
    J Biomol Struct Dyn; 2017 Aug; 35(11):2351-2362. PubMed ID: 27494802
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Design, synthesis, and antiproliferative and CDK2-cyclin a inhibitory activity of novel flavopiridol analogues.
    Ahn YM; Vogeti L; Liu CJ; Santhapuram HK; White JM; Vasandani V; Mitscher LA; Lushington GH; Hanson PR; Powell DR; Himes RH; Roby KF; Ye Q; Georg GI
    Bioorg Med Chem; 2007 Jan; 15(2):702-13. PubMed ID: 17123821
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Analysing the Effect of Mutation on Protein Function and Discovering Potential Inhibitors of CDK4: Molecular Modelling and Dynamics Studies.
    N N; Zhu H; Liu J; V K; C GP; Chakraborty C; Chen L
    PLoS One; 2015; 10(8):e0133969. PubMed ID: 26252490
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Molecular dynamics simulation studies for DNA sequence recognition by reactive metabolites of anticancer compounds.
    Tumbi KM; Nandekar PP; Shaikh N; Kesharwani SS; Sangamwar AT
    J Mol Recognit; 2014 Mar; 27(3):138-50. PubMed ID: 24446378
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Sequence-dependent binding of flavonoids to duplex DNA.
    Mitrasinovic PM
    J Chem Inf Model; 2015 Feb; 55(2):421-33. PubMed ID: 25580618
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structure-activity relationship studies of flavopiridol analogues.
    Murthi KK; Dubay M; McClure C; Brizuela L; Boisclair MD; Worland PJ; Mansuri MM; Pal K
    Bioorg Med Chem Lett; 2000 May; 10(10):1037-41. PubMed ID: 10843211
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Exploring therapeutic potential of Rutin by investigating its cyclin-dependent kinase 6 inhibitory activity and binding affinity.
    Yousuf M; Khan S; Hussain A; Alajmi MF; Shamsi A; Haque QMR; Islam A; Hassan MI
    Int J Biol Macromol; 2024 Apr; 264(Pt 2):130624. PubMed ID: 38453105
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A structure-differential binding method for elucidating the interactions between flavonoids and cytochrome-c by ESI-MS and molecular docking.
    Wang X; Liu Y; Wang H
    Talanta; 2013 Nov; 116():368-75. PubMed ID: 24148417
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.