BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

412 related articles for article (PubMed ID: 22172720)

  • 1. β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas.
    Damsky WE; Curley DP; Santhanakrishnan M; Rosenbaum LE; Platt JT; Gould Rothberg BE; Taketo MM; Dankort D; Rimm DL; McMahon M; Bosenberg M
    Cancer Cell; 2011 Dec; 20(6):741-54. PubMed ID: 22172720
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma.
    Scortegagna M; Ruller C; Feng Y; Lazova R; Kluger H; Li JL; De SK; Rickert R; Pellecchia M; Bosenberg M; Ronai ZA
    Oncogene; 2014 Aug; 33(34):4330-9. PubMed ID: 24037523
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Abl kinase regulation by BRAF/ERK and cooperation with Akt in melanoma.
    Jain A; Tripathi R; Turpin CP; Wang C; Plattner R
    Oncogene; 2017 Aug; 36(32):4585-4596. PubMed ID: 28368422
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activated MEK cooperates with Cdkn2a and Pten loss to promote the development and maintenance of melanoma.
    Yang H; Kircher DA; Kim KH; Grossmann AH; VanBrocklin MW; Holmen SL; Robinson JP
    Oncogene; 2017 Jul; 36(27):3842-3851. PubMed ID: 28263969
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.
    Vredeveld LC; Possik PA; Smit MA; Meissl K; Michaloglou C; Horlings HM; Ajouaou A; Kortman PC; Dankort D; McMahon M; Mooi WJ; Peeper DS
    Genes Dev; 2012 May; 26(10):1055-69. PubMed ID: 22549727
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity.
    Conde-Perez A; Gros G; Longvert C; Pedersen M; Petit V; Aktary Z; Viros A; Gesbert F; Delmas V; Rambow F; Bastian BC; Campbell AD; Colombo S; Puig I; Bellacosa A; Sansom O; Marais R; Van Kempen LC; Larue L
    Nat Commun; 2015 Aug; 6():8093. PubMed ID: 26307673
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cooperative interactions of PTEN deficiency and RAS activation in melanoma metastasis.
    Nogueira C; Kim KH; Sung H; Paraiso KH; Dannenberg JH; Bosenberg M; Chin L; Kim M
    Oncogene; 2010 Nov; 29(47):6222-32. PubMed ID: 20711233
    [TBL] [Abstract][Full Text] [Related]  

  • 8. EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation.
    Zingg D; Debbache J; Peña-Hernández R; Antunes AT; Schaefer SM; Cheng PF; Zimmerli D; Haeusel J; Calçada RR; Tuncer E; Zhang Y; Bossart R; Wong KK; Basler K; Dummer R; Santoro R; Levesque MP; Sommer L
    Cancer Cell; 2018 Jul; 34(1):69-84.e14. PubMed ID: 30008323
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppression of MAPK signaling in BRAF-activated PTEN-deficient melanoma by blocking β-catenin signaling in cancer-associated fibroblasts.
    Zhou L; Yang K; Dunaway S; Abdel-Malek Z; Andl T; Kadekaro AL; Zhang Y
    Pigment Cell Melanoma Res; 2018 Mar; 31(2):297-307. PubMed ID: 29045061
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells.
    Gopal YN; Deng W; Woodman SE; Komurov K; Ram P; Smith PD; Davies MA
    Cancer Res; 2010 Nov; 70(21):8736-47. PubMed ID: 20959481
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model.
    Chien AJ; Moore EC; Lonsdorf AS; Kulikauskas RM; Rothberg BG; Berger AJ; Major MB; Hwang ST; Rimm DL; Moon RT
    Proc Natl Acad Sci U S A; 2009 Jan; 106(4):1193-8. PubMed ID: 19144919
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Knockout of MDA-9/Syntenin (SDCBP) expression in the microenvironment dampens tumor-supporting inflammation and inhibits melanoma metastasis.
    Das SK; Guo C; Pradhan AK; Bhoopathi P; Talukdar S; Shen XN; Emdad L; Subler MA; Windle JJ; Sarkar D; Wang XY; Fisher PB
    Oncotarget; 2016 Jul; 7(30):46848-46861. PubMed ID: 27341128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Aryl hydrocarbon receptor/cytochrome P450 1A1 pathway mediates breast cancer stem cells expansion through PTEN inhibition and β-Catenin and Akt activation.
    Al-Dhfyan A; Alhoshani A; Korashy HM
    Mol Cancer; 2017 Jan; 16(1):14. PubMed ID: 28103884
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Small GTPase ARF6 Activates PI3K in Melanoma to Induce a Prometastatic State.
    Yoo JH; Brady SW; Acosta-Alvarez L; Rogers A; Peng J; Sorensen LK; Wolff RK; Mleynek T; Shin D; Rich CP; Kircher DA; Bild A; Odelberg SJ; Li DY; Holmen SL; Grossmann AH
    Cancer Res; 2019 Jun; 79(11):2892-2908. PubMed ID: 31048499
    [TBL] [Abstract][Full Text] [Related]  

  • 15. KLF9-dependent ROS regulate melanoma progression in stage-specific manner.
    Bagati A; Moparthy S; Fink EE; Bianchi-Smiraglia A; Yun DH; Kolesnikova M; Udartseva OO; Wolff DW; Roll MV; Lipchick BC; Han Z; Kozlova NI; Jowdy P; Berman AE; Box NF; Rodriguez C; Bshara W; Kandel ES; Soengas MS; Paragh G; Nikiforov MA
    Oncogene; 2019 May; 38(19):3585-3597. PubMed ID: 30664687
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MC1R is a potent regulator of PTEN after UV exposure in melanocytes.
    Cao J; Wan L; Hacker E; Dai X; Lenna S; Jimenez-Cervantes C; Wang Y; Leslie NR; Xu GX; Widlund HR; Ryu B; Alani RM; Dutton-Regester K; Goding CR; Hayward NK; Wei W; Cui R
    Mol Cell; 2013 Aug; 51(4):409-22. PubMed ID: 23973372
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activated Hgf-Met Signaling Cooperates with Oncogenic BRAF to Drive Primary Cutaneous Melanomas and Angiotropic Lung Metastases in Mice.
    Braun AD; Mengoni M; Bonifatius S; Tüting T; Gaffal E
    J Invest Dermatol; 2020 Jul; 140(7):1410-1417.e2. PubMed ID: 31972251
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential AKT dependency displayed by mouse models of BRAFV600E-initiated melanoma.
    Marsh Durban V; Deuker MM; Bosenberg MW; Phillips W; McMahon M
    J Clin Invest; 2013 Dec; 123(12):5104-18. PubMed ID: 24200692
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Patterns of immune-cell infiltration in murine models of melanoma: roles of antigen and tissue site in creating inflamed tumors.
    Leick KM; Pinczewski J; Mauldin IS; Young SJ; Deacon DH; Woods AN; Bosenberg MW; Engelhard VH; Slingluff CL
    Cancer Immunol Immunother; 2019 Jul; 68(7):1121-1132. PubMed ID: 31134297
    [TBL] [Abstract][Full Text] [Related]  

  • 20. AKT1 Activation Promotes Development of Melanoma Metastases.
    Cho JH; Robinson JP; Arave RA; Burnett WJ; Kircher DA; Chen G; Davies MA; Grossmann AH; VanBrocklin MW; McMahon M; Holmen SL
    Cell Rep; 2015 Nov; 13(5):898-905. PubMed ID: 26565903
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.