BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 22172944)

  • 1. Tumor suppressor cell adhesion molecule 1 (CADM1) is cleaved by a disintegrin and metalloprotease 10 (ADAM10) and subsequently cleaved by γ-secretase complex.
    Nagara Y; Hagiyama M; Hatano N; Futai E; Suo S; Takaoka Y; Murakami Y; Ito A; Ishiura S
    Biochem Biophys Res Commun; 2012 Jan; 417(1):462-7. PubMed ID: 22172944
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Coxsackievirus and Adenovirus Receptor (CAR) undergoes ectodomain shedding and regulated intramembrane proteolysis (RIP).
    Houri N; Huang KC; Nalbantoglu J
    PLoS One; 2013; 8(8):e73296. PubMed ID: 24015300
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes.
    Hundhausen C; Schulte A; Schulz B; Andrzejewski MG; Schwarz N; von Hundelshausen P; Winter U; Paliga K; Reiss K; Saftig P; Weber C; Ludwig A
    J Immunol; 2007 Jun; 178(12):8064-72. PubMed ID: 17548644
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10.
    Abel S; Hundhausen C; Mentlein R; Schulte A; Berkhout TA; Broadway N; Hartmann D; Sedlacek R; Dietrich S; Muetze B; Schuster B; Kallen KJ; Saftig P; Rose-John S; Ludwig A
    J Immunol; 2004 May; 172(10):6362-72. PubMed ID: 15128827
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alpha-secretase activity of the disintegrin metalloprotease ADAM 10. Influences of domain structure.
    Fahrenholz F; Gilbert S; Kojro E; Lammich S; Postina R
    Ann N Y Acad Sci; 2000; 920():215-22. PubMed ID: 11193153
    [TBL] [Abstract][Full Text] [Related]  

  • 6. L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth.
    Maretzky T; Schulte M; Ludwig A; Rose-John S; Blobel C; Hartmann D; Altevogt P; Saftig P; Reiss K
    Mol Cell Biol; 2005 Oct; 25(20):9040-53. PubMed ID: 16199880
    [TBL] [Abstract][Full Text] [Related]  

  • 7. T-cell immunoglobulin and mucin domain 2 (TIM-2) is a target of ADAM10-mediated ectodomain shedding.
    Dewitz C; Möller-Hackbarth K; Schweigert O; Reiss K; Chalaris A; Scheller J; Rose-John S
    FEBS J; 2014 Jan; 281(1):157-74. PubMed ID: 24164679
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A.
    Herzog C; Haun RS; Ludwig A; Shah SV; Kaushal GP
    J Biol Chem; 2014 May; 289(19):13308-22. PubMed ID: 24662289
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 (CD44) and of Neuregulin-1 Requires Substrate Dimerization.
    Hartmann M; Parra LM; Ruschel A; Lindner C; Morrison H; Herrlich A; Herrlich P
    J Biol Chem; 2015 Jul; 290(28):17041-54. PubMed ID: 25925953
    [TBL] [Abstract][Full Text] [Related]  

  • 10. EphrinA/EphA-induced ectodomain shedding of neural cell adhesion molecule regulates growth cone repulsion through ADAM10 metalloprotease.
    Brennaman LH; Moss ML; Maness PF
    J Neurochem; 2014 Jan; 128(2):267-79. PubMed ID: 24117969
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase.
    Tousseyn T; Thathiah A; Jorissen E; Raemaekers T; Konietzko U; Reiss K; Maes E; Snellinx A; Serneels L; Nyabi O; Annaert W; Saftig P; Hartmann D; De Strooper B
    J Biol Chem; 2009 Apr; 284(17):11738-47. PubMed ID: 19213735
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons.
    Hsia HE; Tüshaus J; Feng X; Hofmann LI; Wefers B; Marciano DK; Wurst W; Lichtenthaler SF
    FASEB J; 2021 Sep; 35(9):e21813. PubMed ID: 34390512
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8.
    Naus S; Reipschläger S; Wildeboer D; Lichtenthaler SF; Mitterreiter S; Guan Z; Moss ML; Bartsch JW
    Biol Chem; 2006 Mar; 387(3):337-46. PubMed ID: 16542157
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity.
    Riedle S; Kiefel H; Gast D; Bondong S; Wolterink S; Gutwein P; Altevogt P
    Biochem J; 2009 May; 420(3):391-402. PubMed ID: 19260824
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4 generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to phosphatidylserine.
    Schweigert O; Dewitz C; Möller-Hackbarth K; Trad A; Garbers C; Rose-John S; Scheller J
    Biochim Biophys Acta; 2014 Feb; 1843(2):275-87. PubMed ID: 24286866
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A soluble form of the receptor for advanced glycation endproducts (RAGE) is produced by proteolytic cleavage of the membrane-bound form by the sheddase a disintegrin and metalloprotease 10 (ADAM10).
    Raucci A; Cugusi S; Antonelli A; Barabino SM; Monti L; Bierhaus A; Reiss K; Saftig P; Bianchi ME
    FASEB J; 2008 Oct; 22(10):3716-27. PubMed ID: 18603587
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growth.
    Stoeck A; Shang L; Dempsey PJ
    J Cell Sci; 2010 Jul; 123(Pt 13):2319-31. PubMed ID: 20530572
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of ADAM10 as a major TNF sheddase in ADAM17-deficient fibroblasts.
    Mezyk-Kopeć R; Bzowska M; Stalińska K; Chełmicki T; Podkalicki M; Jucha J; Kowalczyk K; Mak P; Bereta J
    Cytokine; 2009 Jun; 46(3):309-15. PubMed ID: 19346138
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The intracellular domain of cell adhesion molecule 1 is present in emphysematous lungs and induces lung epithelial cell apoptosis.
    Hagiyama M; Yoneshige A; Inoue T; Sato Y; Mimae T; Okada M; Ito A
    J Biomed Sci; 2015 Aug; 22(1):67. PubMed ID: 26259600
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases.
    Koenen RR; Pruessmeyer J; Soehnlein O; Fraemohs L; Zernecke A; Schwarz N; Reiss K; Sarabi A; Lindbom L; Hackeng TM; Weber C; Ludwig A
    Blood; 2009 May; 113(19):4799-809. PubMed ID: 19258599
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.