These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
299 related articles for article (PubMed ID: 22174087)
1. Hyperactive BMP signaling induced by ALK2(R206H) requires type II receptor function in a Drosophila model for classic fibrodysplasia ossificans progressiva. Le VQ; Wharton KA Dev Dyn; 2012 Jan; 241(1):200-14. PubMed ID: 22174087 [TBL] [Abstract][Full Text] [Related]
2. Drosophila models of FOP provide mechanistic insight. Le V; Anderson E; Akiyama T; Wharton KA Bone; 2018 Apr; 109():192-200. PubMed ID: 29128351 [TBL] [Abstract][Full Text] [Related]
3. ALK2 R206H mutation linked to fibrodysplasia ossificans progressiva confers constitutive activity to the BMP type I receptor and sensitizes mesenchymal cells to BMP-induced osteoblast differentiation and bone formation. van Dinther M; Visser N; de Gorter DJ; Doorn J; Goumans MJ; de Boer J; ten Dijke P J Bone Miner Res; 2010 Jun; 25(6):1208-15. PubMed ID: 19929436 [TBL] [Abstract][Full Text] [Related]
5. Establishment of a novel model of chondrogenesis using murine embryonic stem cells carrying fibrodysplasia ossificans progressiva-associated mutant ALK2. Fujimoto M; Ohte S; Shin M; Yoneyama K; Osawa K; Miyamoto A; Tsukamoto S; Mizuta T; Kokabu S; Machiya A; Okuda A; Suda N; Katagiri T Biochem Biophys Res Commun; 2014 Dec; 455(3-4):347-52. PubMed ID: 25446088 [TBL] [Abstract][Full Text] [Related]
6. Insight into Molecular Mechanism for Activin A-Induced Bone Morphogenetic Protein Signaling. Xie C; Jiang W; Lacroix JJ; Luo Y; Hao J Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32899497 [TBL] [Abstract][Full Text] [Related]
7. A novel mutation of ALK2, L196P, found in the most benign case of fibrodysplasia ossificans progressiva activates BMP-specific intracellular signaling equivalent to a typical mutation, R206H. Ohte S; Shin M; Sasanuma H; Yoneyama K; Akita M; Ikebuchi K; Jimi E; Maruki Y; Matsuoka M; Namba A; Tomoda H; Okazaki Y; Ohtake A; Oda H; Owan I; Yoda T; Furuya H; Kamizono J; Kitoh H; Nakashima Y; Susami T; Haga N; Komori T; Katagiri T Biochem Biophys Res Commun; 2011 Apr; 407(1):213-8. PubMed ID: 21377447 [TBL] [Abstract][Full Text] [Related]
8. Mutant activin-like kinase 2 in fibrodysplasia ossificans progressiva are activated via T203 by BMP type II receptors. Fujimoto M; Ohte S; Osawa K; Miyamoto A; Tsukamoto S; Mizuta T; Kokabu S; Suda N; Katagiri T Mol Endocrinol; 2015 Jan; 29(1):140-52. PubMed ID: 25354296 [TBL] [Abstract][Full Text] [Related]
9. Functional analysis of saxophone, the Drosophila gene encoding the BMP type I receptor ortholog of human ALK1/ACVRL1 and ACVR1/ALK2. Twombly V; Bangi E; Le V; Malnic B; Singer MA; Wharton KA Genetics; 2009 Oct; 183(2):563-79, 1SI-8SI. PubMed ID: 19620392 [TBL] [Abstract][Full Text] [Related]
11. An ALK2 inhibitor, BLU-782, prevents heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva. Davis AJ; Brooijmans N; Brubaker JD; Stevison F; LaBranche TP; Albayya F; Fleming P; Hodous BL; Kim JL; Kim S; Lobbardi R; Palmer M; Sheets MP; Vassiliadis J; Wang R; Williams BD; Wilson D; Xu L; Zhu XJ; Bouchard K; Hunter JW; Graul C; Greenblatt E; Hussein A; Lyon M; Russo J; Stewart R; Dorsch M; Guzi TJ; Kadambi V; Lengauer C; Garner AP Sci Transl Med; 2024 May; 16(749):eabp8334. PubMed ID: 38809966 [TBL] [Abstract][Full Text] [Related]
12. Reduced GS Domain Serine/Threonine Requirements of Fibrodysplasia Ossificans Progressiva Mutant Type I BMP Receptor ACVR1 in the Zebrafish. Allen RS; Jones WD; Hale M; Warder BN; Shore EM; Mullins MC J Bone Miner Res; 2023 Sep; 38(9):1364-1385. PubMed ID: 37329499 [TBL] [Abstract][Full Text] [Related]
13. Depletion of Mast Cells and Macrophages Impairs Heterotopic Ossification in an Acvr1 Convente MR; Chakkalakal SA; Yang E; Caron RJ; Zhang D; Kambayashi T; Kaplan FS; Shore EM J Bone Miner Res; 2018 Feb; 33(2):269-282. PubMed ID: 28986986 [TBL] [Abstract][Full Text] [Related]
14. Activation of G Ebner JK; König GM; Kostenis E; Siegert P; Aktories K; Orth JHC Bone; 2019 Oct; 127():592-601. PubMed ID: 31376533 [TBL] [Abstract][Full Text] [Related]