These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 22174676)

  • 21. NPC intracellular cholesterol transporter 1 (NPC1)-mediated cholesterol export from lysosomes.
    Pfeffer SR
    J Biol Chem; 2019 Feb; 294(5):1706-1709. PubMed ID: 30710017
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Lipid homeostasis and lipoprotein secretion in Niemann-Pick C1-deficient hepatocytes.
    Kulinski A; Vance JE
    J Biol Chem; 2007 Jan; 282(3):1627-37. PubMed ID: 17107950
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mechanisms and consequences of impaired lipid trafficking in Niemann-Pick type C1-deficient mammalian cells.
    Karten B; Peake KB; Vance JE
    Biochim Biophys Acta; 2009 Jul; 1791(7):659-70. PubMed ID: 19416638
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Novel roles for ATP-binding cassette G transporters in lipid redistribution in Toxoplasma.
    Ehrenman K; Sehgal A; Lige B; Stedman TT; Joiner KA; Coppens I
    Mol Microbiol; 2010 Jun; 76(5):1232-49. PubMed ID: 20487267
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Characterization of a second sterol-esterifying enzyme in Toxoplasma highlights the importance of cholesterol storage pathways for the parasite.
    Lige B; Sampels V; Coppens I
    Mol Microbiol; 2013 Mar; 87(5):951-67. PubMed ID: 23374239
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts.
    Pipalia NH; Cosner CC; Huang A; Chatterjee A; Bourbon P; Farley N; Helquist P; Wiest O; Maxfield FR
    Proc Natl Acad Sci U S A; 2011 Apr; 108(14):5620-5. PubMed ID: 21436030
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Niemann-Pick C1 disease: correlations between NPC1 mutations, levels of NPC1 protein, and phenotypes emphasize the functional significance of the putative sterol-sensing domain and of the cysteine-rich luminal loop.
    Millat G; Marçais C; Tomasetto C; Chikh K; Fensom AH; Harzer K; Wenger DA; Ohno K; Vanier MT
    Am J Hum Genet; 2001 Jun; 68(6):1373-85. PubMed ID: 11333381
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis.
    Carstea ED; Morris JA; Coleman KG; Loftus SK; Zhang D; Cummings C; Gu J; Rosenfeld MA; Pavan WJ; Krizman DB; Nagle J; Polymeropoulos MH; Sturley SL; Ioannou YA; Higgins ME; Comly M; Cooney A; Brown A; Kaneski CR; Blanchette-Mackie EJ; Dwyer NK; Neufeld EB; Chang TY; Liscum L; Strauss JF; Ohno K; Zeigler M; Carmi R; Sokol J; Markie D; O'Neill RR; van Diggelen OP; Elleder M; Patterson MC; Brady RO; Vanier MT; Pentchev PG; Tagle DA
    Science; 1997 Jul; 277(5323):228-31. PubMed ID: 9211849
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The structure and function of the Niemann-Pick C1 protein.
    Ioannou YA
    Mol Genet Metab; 2000; 71(1-2):175-81. PubMed ID: 11001808
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A Lipolytic Lecithin:Cholesterol Acyltransferase Secreted by Toxoplasma Facilitates Parasite Replication and Egress.
    Pszenny V; Ehrenman K; Romano JD; Kennard A; Schultz A; Roos DS; Grigg ME; Carruthers VB; Coppens I
    J Biol Chem; 2016 Feb; 291(8):3725-46. PubMed ID: 26694607
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells.
    Rujoi M; Pipalia NH; Maxfield FR
    PLoS One; 2010 Sep; 5(9):e12788. PubMed ID: 20877719
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Flux of fatty acids through NPC1 lysosomes.
    Passeggio J; Liscum L
    J Biol Chem; 2005 Mar; 280(11):10333-9. PubMed ID: 15632139
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution.
    Malathi K; Higaki K; Tinkelenberg AH; Balderes DA; Almanzar-Paramio D; Wilcox LJ; Erdeniz N; Redican F; Padamsee M; Liu Y; Khan S; Alcantara F; Carstea ED; Morris JA; Sturley SL
    J Cell Biol; 2004 Feb; 164(4):547-56. PubMed ID: 14970192
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mutation analysis of feline Niemann-Pick C1 disease.
    Somers KL; Royals MA; Carstea ED; Rafi MA; Wenger DA; Thrall MA
    Mol Genet Metab; 2003 Jun; 79(2):99-103. PubMed ID: 12809639
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Targeting of NPC1 to late endosomes involves multiple signals, including one residing within the putative sterol-sensing domain.
    Scott C; Higgins ME; Davies JP; Ioannou YA
    J Biol Chem; 2004 Nov; 279(46):48214-23. PubMed ID: 15347664
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Role of Niemann-Pick type C1 protein in intracellular trafficking of low density lipoprotein-derived cholesterol.
    Cruz JC; Sugii S; Yu C; Chang TY
    J Biol Chem; 2000 Feb; 275(6):4013-21. PubMed ID: 10660558
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Iron Limitation Restores Autophagy and Increases Lifespan in the Yeast Model of Niemann-Pick Type C1.
    Martins TS; Costa RS; Vilaça R; Lemos C; Teixeira V; Pereira C; Costa V
    Int J Mol Sci; 2023 Mar; 24(7):. PubMed ID: 37047194
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Endosomal/lysosomal processing of gangliosides affects neuronal cholesterol sequestration in Niemann-Pick disease type C.
    Zhou S; Davidson C; McGlynn R; Stephney G; Dobrenis K; Vanier MT; Walkley SU
    Am J Pathol; 2011 Aug; 179(2):890-902. PubMed ID: 21708114
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Lysosomal unesterified cholesterol content correlates with liver cell death in murine Niemann-Pick type C disease.
    Beltroy EP; Liu B; Dietschy JM; Turley SD
    J Lipid Res; 2007 Apr; 48(4):869-81. PubMed ID: 17220530
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with Ezetimibe.
    Huang W; Xiong Q; Lin M; Rikihisa Y
    mBio; 2021 Oct; 12(5):e0229921. PubMed ID: 34544283
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.