BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

420 related articles for article (PubMed ID: 22179316)

  • 21. Effects of Aluminium on Long-Term Memory in Rats and on SIRT1 Mediating the Transcription of CREB-Dependent Gene in Hippocampus.
    Yan D; Jin C; Cao Y; Wang L; Lu X; Yang J; Wu S; Cai Y
    Basic Clin Pharmacol Toxicol; 2017 Oct; 121(4):342-352. PubMed ID: 28429887
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease.
    Bithell A; Johnson R; Buckley NJ
    Biochem Soc Trans; 2009 Dec; 37(Pt 6):1270-5. PubMed ID: 19909260
    [TBL] [Abstract][Full Text] [Related]  

  • 23. CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability.
    Noriega LG; Feige JN; Canto C; Yamamoto H; Yu J; Herman MA; Mataki C; Kahn BB; Auwerx J
    EMBO Rep; 2011 Sep; 12(10):1069-76. PubMed ID: 21836635
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease.
    Valencia A; Reeves PB; Sapp E; Li X; Alexander J; Kegel KB; Chase K; Aronin N; DiFiglia M
    J Neurosci Res; 2010 Jan; 88(1):179-90. PubMed ID: 19642201
    [TBL] [Abstract][Full Text] [Related]  

  • 25. SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice.
    Tulino R; Benjamin AC; Jolinon N; Smith DL; Chini EN; Carnemolla A; Bates GP
    PLoS One; 2016; 11(1):e0145425. PubMed ID: 26815359
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Decreased cAMP response element-mediated transcription: an early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis.
    Sugars KL; Brown R; Cook LJ; Swartz J; Rubinsztein DC
    J Biol Chem; 2004 Feb; 279(6):4988-99. PubMed ID: 14627700
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.
    Canals JM; Pineda JR; Torres-Peraza JF; Bosch M; Martín-Ibañez R; Muñoz MT; Mengod G; Ernfors P; Alberch J
    J Neurosci; 2004 Sep; 24(35):7727-39. PubMed ID: 15342740
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.
    Zhang H; Li Q; Graham RK; Slow E; Hayden MR; Bezprozvanny I
    Neurobiol Dis; 2008 Jul; 31(1):80-8. PubMed ID: 18502655
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.
    Cui L; Jeong H; Borovecki F; Parkhurst CN; Tanese N; Krainc D
    Cell; 2006 Oct; 127(1):59-69. PubMed ID: 17018277
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Role of Phosphodiesterases in Huntington's Disease.
    Fusco FR; Paldino E
    Adv Neurobiol; 2017; 17():285-304. PubMed ID: 28956337
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Transcriptional profiles for distinct aggregation states of mutant Huntingtin exon 1 protein unmask new Huntington's disease pathways.
    Moily NS; Ormsby AR; Stojilovic A; Ramdzan YM; Diesch J; Hannan RD; Zajac MS; Hannan AJ; Oshlack A; Hatters DM
    Mol Cell Neurosci; 2017 Sep; 83():103-112. PubMed ID: 28743452
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Potential role of TrkB agonist in neuronal survival by promoting CREB/BDNF and PI3K/Akt signaling in vitro and in vivo model of 3-nitropropionic acid (3-NP)-induced neuronal death.
    Ahmed S; Kwatra M; Gawali B; Panda SR; Naidu VGM
    Apoptosis; 2021 Feb; 26(1-2):52-70. PubMed ID: 33226552
    [TBL] [Abstract][Full Text] [Related]  

  • 33. AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington's disease.
    Zuleta A; Vidal RL; Armentano D; Parsons G; Hetz C
    Biochem Biophys Res Commun; 2012 Apr; 420(3):558-63. PubMed ID: 22445760
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.
    Hermel E; Gafni J; Propp SS; Leavitt BR; Wellington CL; Young JE; Hackam AS; Logvinova AV; Peel AL; Chen SF; Hook V; Singaraja R; Krajewski S; Goldsmith PC; Ellerby HM; Hayden MR; Bredesen DE; Ellerby LM
    Cell Death Differ; 2004 Apr; 11(4):424-38. PubMed ID: 14713958
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.
    Wellington CL; Ellerby LM; Gutekunst CA; Rogers D; Warby S; Graham RK; Loubser O; van Raamsdonk J; Singaraja R; Yang YZ; Gafni J; Bredesen D; Hersch SM; Leavitt BR; Roy S; Nicholson DW; Hayden MR
    J Neurosci; 2002 Sep; 22(18):7862-72. PubMed ID: 12223539
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models.
    Sontag EM; Lotz GP; Agrawal N; Tran A; Aron R; Yang G; Necula M; Lau A; Finkbeiner S; Glabe C; Marsh JL; Muchowski PJ; Thompson LM
    J Neurosci; 2012 Aug; 32(32):11109-19. PubMed ID: 22875942
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin.
    Jiang H; Poirier MA; Liang Y; Pei Z; Weiskittel CE; Smith WW; DeFranco DB; Ross CA
    Neurobiol Dis; 2006 Sep; 23(3):543-51. PubMed ID: 16766198
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain.
    Ginés S; Bosch M; Marco S; Gavaldà N; Díaz-Hernández M; Lucas JJ; Canals JM; Alberch J
    Eur J Neurosci; 2006 Feb; 23(3):649-58. PubMed ID: 16487146
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Huntingtin-protein interactions and the pathogenesis of Huntington's disease.
    Li SH; Li XJ
    Trends Genet; 2004 Mar; 20(3):146-54. PubMed ID: 15036808
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mutant huntingtin impairs the post-Golgi trafficking of brain-derived neurotrophic factor but not its Val66Met polymorphism.
    del Toro D; Canals JM; Ginés S; Kojima M; Egea G; Alberch J
    J Neurosci; 2006 Dec; 26(49):12748-57. PubMed ID: 17151278
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 21.