BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 22179554)

  • 1. Increased longevity and metabolic correction following syngeneic BMT in a murine model of mucopolysaccharidosis type I.
    Wolf DA; Lenander AW; Nan Z; Braunlin EA; Podetz-Pedersen KM; Whitley CB; Gupta P; Low WC; McIvor RS
    Bone Marrow Transplant; 2012 Sep; 47(9):1235-40. PubMed ID: 22179554
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of an MPS I-H knock-in mouse that carries a nonsense mutation analogous to the human IDUA-W402X mutation.
    Wang D; Shukla C; Liu X; Schoeb TR; Clarke LA; Bedwell DM; Keeling KM
    Mol Genet Metab; 2010 Jan; 99(1):62-71. PubMed ID: 19751987
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Long-term nonsense suppression therapy moderates MPS I-H disease progression.
    Gunn G; Dai Y; Du M; Belakhov V; Kandasamy J; Schoeb TR; Baasov T; Bedwell DM; Keeling KM
    Mol Genet Metab; 2014 Mar; 111(3):374-381. PubMed ID: 24411223
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bone marrow transplantation for feline mucopolysaccharidosis I.
    Ellinwood NM; Colle MA; Weil MA; Casal ML; Vite CH; Wiemelt S; Hasson CW; O'Malley TM; He X; Prociuk U; Verot L; Melniczek JR; Lannon A; Aguirre GD; Knox VW; Evans SM; Vanier MT; Schuchman EH; Walkley SU; Haskins ME
    Mol Genet Metab; 2007 Jul; 91(3):239-50. PubMed ID: 17482862
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High-dose enzyme replacement therapy in murine Hurler syndrome.
    Ou L; Herzog T; Koniar BL; Gunther R; Whitley CB
    Mol Genet Metab; 2014 Feb; 111(2):116-22. PubMed ID: 24100243
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparison of Endovascular and Intraventricular Gene Therapy With Adeno-Associated Virus-α-L-Iduronidase for Hurler Disease.
    Janson CG; Romanova LG; Leone P; Nan Z; Belur L; McIvor RS; Low WC
    Neurosurgery; 2014 Jan; 74(1):99-111. PubMed ID: 24077583
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The designer aminoglycoside NB84 significantly reduces glycosaminoglycan accumulation associated with MPS I-H in the Idua-W392X mouse.
    Wang D; Belakhov V; Kandasamy J; Baasov T; Li SC; Li YT; Bedwell DM; Keeling KM
    Mol Genet Metab; 2012 Jan; 105(1):116-25. PubMed ID: 22056610
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evidence that glycosaminoglycan storage and collagen deposition in the cauda epididymidis does not impair sperm viability in the Mucopolysaccharidosis type I mouse model.
    do Nascimento CC; Aguiar O; Viana GM; D Almeida V
    Reprod Fertil Dev; 2020 Feb; 32(3):304-312. PubMed ID: 31679559
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lipid composition of whole brain and cerebellum in Hurler syndrome (MPS IH) mice.
    Heinecke KA; Peacock BN; Blazar BR; Tolar J; Seyfried TN
    Neurochem Res; 2011 Sep; 36(9):1669-76. PubMed ID: 21253856
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neonatal bone marrow transplantation prevents bone pathology in a mouse model of mucopolysaccharidosis type I.
    Pievani A; Azario I; Antolini L; Shimada T; Patel P; Remoli C; Rambaldi B; Valsecchi MG; Riminucci M; Biondi A; Tomatsu S; Serafini M
    Blood; 2015 Mar; 125(10):1662-71. PubMed ID: 25298037
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impaired bone remodeling and its correction by combination therapy in a mouse model of mucopolysaccharidosis-I.
    Kuehn SC; Koehne T; Cornils K; Markmann S; Riedel C; Pestka JM; Schweizer M; Baldauf C; Yorgan TA; Krause M; Keller J; Neven M; Breyer S; Stuecker R; Muschol N; Busse B; Braulke T; Fehse B; Amling M; Schinke T
    Hum Mol Genet; 2015 Dec; 24(24):7075-86. PubMed ID: 26427607
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Residual α-L-iduronidase activity in fibroblasts of mild to severe Mucopolysaccharidosis type I patients.
    Oussoren E; Keulemans J; van Diggelen OP; Oemardien LF; Timmermans RG; van der Ploeg AT; Ruijter GJ
    Mol Genet Metab; 2013 Aug; 109(4):377-81. PubMed ID: 23786846
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Treatment of the mouse model of mucopolysaccharidosis I with retrovirally transduced bone marrow.
    Zheng Y; Rozengurt N; Ryazantsev S; Kohn DB; Satake N; Neufeld EF
    Mol Genet Metab; 2003 Aug; 79(4):233-44. PubMed ID: 12948739
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biomechanical and histological characterization of MPS I mice femurs.
    Ferreira NY; do Nascimento CC; Pereira VG; de Oliveira F; Medalha CC; da Silva VC; D'Almeida V
    Acta Histochem; 2021 Feb; 123(2):151678. PubMed ID: 33434858
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reprogramming erythroid cells for lysosomal enzyme production leads to visceral and CNS cross-correction in mice with Hurler syndrome.
    Wang D; Zhang W; Kalfa TA; Grabowski G; Davies S; Malik P; Pan D
    Proc Natl Acad Sci U S A; 2009 Nov; 106(47):19958-63. PubMed ID: 19903883
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gentamicin-mediated suppression of Hurler syndrome stop mutations restores a low level of alpha-L-iduronidase activity and reduces lysosomal glycosaminoglycan accumulation.
    Keeling KM; Brooks DA; Hopwood JJ; Li P; Thompson JN; Bedwell DM
    Hum Mol Genet; 2001 Feb; 10(3):291-9. PubMed ID: 11159948
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RTB lectin-mediated delivery of lysosomal α-l-iduronidase mitigates disease manifestations systemically including the central nervous system.
    Ou L; Przybilla MJ; Koniar B; Whitley CB
    Mol Genet Metab; 2018 Feb; 123(2):105-111. PubMed ID: 29198892
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification and molecular characterization of alpha-L-iduronidase mutations present in mucopolysaccharidosis type I patients undergoing enzyme replacement therapy.
    Yogalingam G; Guo XH; Muller VJ; Brooks DA; Clements PR; Kakkis ED; Hopwood JJ
    Hum Mutat; 2004 Sep; 24(3):199-207. PubMed ID: 15300847
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neurocognitive and neuropsychiatric phenotypes associated with the mutation L238Q of the α-L-iduronidase gene in Hurler-Scheie syndrome.
    Ahmed A; Whitley CB; Cooksley R; Rudser K; Cagle S; Ali N; Delaney K; Yund B; Shapiro E
    Mol Genet Metab; 2014 Feb; 111(2):123-7. PubMed ID: 24368159
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Decreased performance in IDUA knockout mouse mimic limitations of joint function and locomotion in patients with Hurler syndrome.
    Kim C; Kwak MJ; Cho SY; Ko AR; Rheey J; Kwon JY; Chung Y; Jin DK
    Orphanet J Rare Dis; 2015 Sep; 10():121. PubMed ID: 26407983
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.