257 related articles for article (PubMed ID: 22183167)
1. Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents.
Eakin AE; Green O; Hales N; Walkup GK; Bist S; Singh A; Mullen G; Bryant J; Embrey K; Gao N; Breeze A; Timms D; Andrews B; Uria-Nickelsen M; Demeritt J; Loch JT; Hull K; Blodgett A; Illingworth RN; Prince B; Boriack-Sjodin PA; Hauck S; MacPherson LJ; Ni H; Sherer B
Antimicrob Agents Chemother; 2012 Mar; 56(3):1240-6. PubMed ID: 22183167
[TBL] [Abstract][Full Text] [Related]
2. Pyrrolamide DNA gyrase inhibitors: optimization of antibacterial activity and efficacy.
Sherer BA; Hull K; Green O; Basarab G; Hauck S; Hill P; Loch JT; Mullen G; Bist S; Bryant J; Boriack-Sjodin A; Read J; DeGrace N; Uria-Nickelsen M; Illingworth RN; Eakin AE
Bioorg Med Chem Lett; 2011 Dec; 21(24):7416-20. PubMed ID: 22041057
[TBL] [Abstract][Full Text] [Related]
3. Novel DNA gyrase inhibitors: microbiological characterisation of pyrrolamides.
Uria-Nickelsen M; Blodgett A; Kamp H; Eakin A; Sherer B; Green O
Int J Antimicrob Agents; 2013 Jan; 41(1):28-35. PubMed ID: 23142086
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors.
Durcik M; Tammela P; Barančoková M; Tomašič T; Ilaš J; Kikelj D; Zidar N
ChemMedChem; 2018 Jan; 13(2):186-198. PubMed ID: 29206345
[TBL] [Abstract][Full Text] [Related]
5. New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity.
Durcik M; Lovison D; Skok Ž; Durante Cruz C; Tammela P; Tomašič T; Benedetto Tiz D; Draskovits G; Nyerges Á; Pál C; Ilaš J; Peterlin Mašič L; Kikelj D; Zidar N
Eur J Med Chem; 2018 Jun; 154():117-132. PubMed ID: 29778894
[TBL] [Abstract][Full Text] [Related]
6. Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099).
Basarab GS; Hill PJ; Garner CE; Hull K; Green O; Sherer BA; Dangel PB; Manchester JI; Bist S; Hauck S; Zhou F; Uria-Nickelsen M; Illingworth R; Alm R; Rooney M; Eakin AE
J Med Chem; 2014 Jul; 57(14):6060-82. PubMed ID: 24959892
[TBL] [Abstract][Full Text] [Related]
7. Dual targeting of DNA gyrase and topoisomerase IV: target interactions of heteroaryl isothiazolones in Staphylococcus aureus.
Cheng J; Thanassi JA; Thoma CL; Bradbury BJ; Deshpande M; Pucci MJ
Antimicrob Agents Chemother; 2007 Jul; 51(7):2445-53. PubMed ID: 17502409
[TBL] [Abstract][Full Text] [Related]
8. New N-phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATPase inhibitors of DNA gyrase.
Zidar N; Tomašič T; Macut H; Sirc A; Brvar M; Montalvão S; Tammela P; Ilaš J; Kikelj D
Eur J Med Chem; 2016 Jul; 117():197-211. PubMed ID: 27100032
[TBL] [Abstract][Full Text] [Related]
9. Mechanistic and Structural Basis for the Actions of the Antibacterial Gepotidacin against Staphylococcus aureus Gyrase.
Gibson EG; Bax B; Chan PF; Osheroff N
ACS Infect Dis; 2019 Apr; 5(4):570-581. PubMed ID: 30757898
[TBL] [Abstract][Full Text] [Related]
10. Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors.
Gjorgjieva M; Tomašič T; Barančokova M; Katsamakas S; Ilaš J; Tammela P; Peterlin Mašič L; Kikelj D
J Med Chem; 2016 Oct; 59(19):8941-8954. PubMed ID: 27541007
[TBL] [Abstract][Full Text] [Related]
11. Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study.
Ibrahim TS; Almalki AJ; Moustafa AH; Allam RM; Abuo-Rahma GEA; El Subbagh HI; Mohamed MFA
Bioorg Chem; 2021 Jun; 111():104885. PubMed ID: 33838559
[TBL] [Abstract][Full Text] [Related]
12. Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Mesleh MF; Cross JB; Zhang J; Kahmann J; Andersen OA; Barker J; Cheng RK; Felicetti B; Wood M; Hadfield AT; Scheich C; Moy TI; Yang Q; Shotwell J; Nguyen K; Lippa B; Dolle R; Ryan MD
Bioorg Med Chem Lett; 2016 Feb; 26(4):1314-8. PubMed ID: 26786695
[TBL] [Abstract][Full Text] [Related]
13. Dual inhibition of Staphylococcus aureus DNA gyrase and topoisomerase IV activity by phenylalanine-derived (Z)-5-arylmethylidene rhodanines.
Werner MM; Patel BA; Talele TT; Ashby CR; Li Z; Zauhar RJ
Bioorg Med Chem; 2015 Sep; 23(18):6125-37. PubMed ID: 26320664
[TBL] [Abstract][Full Text] [Related]
14. Novel quinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV.
Mitton-Fry MJ; Brickner SJ; Hamel JC; Brennan L; Casavant JM; Chen M; Chen T; Ding X; Driscoll J; Hardink J; Hoang T; Hua E; Huband MD; Maloney M; Marfat A; McCurdy SP; McLeod D; Plotkin M; Reilly U; Robinson S; Schafer J; Shepard RM; Smith JF; Stone GG; Subramanyam C; Yoon K; Yuan W; Zaniewski RP; Zook C
Bioorg Med Chem Lett; 2013 May; 23(10):2955-61. PubMed ID: 23566517
[TBL] [Abstract][Full Text] [Related]
15. Discovery of kibdelomycin, a potent new class of bacterial type II topoisomerase inhibitor by chemical-genetic profiling in Staphylococcus aureus.
Phillips JW; Goetz MA; Smith SK; Zink DL; Polishook J; Onishi R; Salowe S; Wiltsie J; Allocco J; Sigmund J; Dorso K; Lee S; Skwish S; de la Cruz M; Martín J; Vicente F; Genilloud O; Lu J; Painter RE; Young K; Overbye K; Donald RG; Singh SB
Chem Biol; 2011 Aug; 18(8):955-65. PubMed ID: 21867911
[TBL] [Abstract][Full Text] [Related]
16. Symmetric bis-benzimidazoles are potent anti-staphylococcal agents with dual inhibitory mechanisms against DNA gyrase.
Dale AG; Hinds J; Mann J; Taylor PW; Neidle S
Biochemistry; 2012 Jul; 51(29):5860-71. PubMed ID: 22746203
[TBL] [Abstract][Full Text] [Related]
17. In Vitro and In Vivo Characterization of the Novel Oxabicyclooctane-Linked Bacterial Topoisomerase Inhibitor AM-8722, a Selective, Potent Inhibitor of Bacterial DNA Gyrase.
Tan CM; Gill CJ; Wu J; Toussaint N; Yin J; Tsuchiya T; Garlisi CG; Kaelin D; Meinke PT; Miesel L; Olsen DB; Lagrutta A; Fukuda H; Kishii R; Takei M; Oohata K; Takeuchi T; Shibue T; Takano H; Nishimura A; Fukuda Y; Singh SB
Antimicrob Agents Chemother; 2016 Aug; 60(8):4830-9. PubMed ID: 27246784
[TBL] [Abstract][Full Text] [Related]
18. Second-generation 4,5,6,7-tetrahydrobenzo[
Lamut A; Skok Ž; Barančoková M; Gutierrez LJ; Cruz CD; Tammela P; Draskovits G; Szili PÉ; Nyerges Á; Pál C; Molek P; Bratkovič T; Ilaš J; Zidar N; Zega A; Enriz RD; Kikelj D; Tomašič T
Future Med Chem; 2020 Feb; 12(4):277-297. PubMed ID: 32043377
[No Abstract] [Full Text] [Related]
19. Structures of kibdelomycin bound to Staphylococcus aureus GyrB and ParE showed a novel U-shaped binding mode.
Lu J; Patel S; Sharma N; Soisson SM; Kishii R; Takei M; Fukuda Y; Lumb KJ; Singh SB
ACS Chem Biol; 2014 Sep; 9(9):2023-31. PubMed ID: 24992706
[TBL] [Abstract][Full Text] [Related]
20. Discovery of novel multi-substituted benzo-indole pyrazole schiff base derivatives with antibacterial activity targeting DNA gyrase.
Liu H; Chu ZW; Xia DG; Cao HQ; Lv XH
Bioorg Chem; 2020 Jun; 99():103807. PubMed ID: 32272364
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
