BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 22184635)

  • 1. High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
    Yang D; Postnikov YV; Li Y; Tewary P; de la Rosa G; Wei F; Klinman D; Gioannini T; Weiss JP; Furusawa T; Bustin M; Oppenheim JJ
    J Exp Med; 2012 Jan; 209(1):157-71. PubMed ID: 22184635
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High-mobility group nucleosome binding domain 1 (HMGN1) functions as a Th1-polarizing alarmin.
    Yang D; Han Z; Alam MM; Oppenheim JJ
    Semin Immunol; 2018 Aug; 38():49-53. PubMed ID: 29503123
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Alarmin HMGN1 contributes to antitumor immunity and is a potent immunoadjuvant.
    Wei F; Yang D; Tewary P; Li Y; Li S; Chen X; Howard OM; Bustin M; Oppenheim JJ
    Cancer Res; 2014 Nov; 74(21):5989-98. PubMed ID: 25205103
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High-Mobility Group Nucleosome-Binding Protein 1 as Endogenous Ligand Induces Innate Immune Tolerance in a TLR4-Sirtuin-1 Dependent Manner in Human Blood Peripheral Mononuclear Cells.
    Arts RJW; Huang PK; Yang D; Joosten LAB; van der Meer JWM; Oppenheim JJ; Netea MG; Cheng SC
    Front Immunol; 2018; 9():526. PubMed ID: 29593748
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Release mechanism of high mobility group nucleosome binding domain 1 from lipopolysaccharide-stimulated macrophages.
    Murakami T; Hu Z; Tamura H; Nagaoka I
    Mol Med Rep; 2016 Apr; 13(4):3115-20. PubMed ID: 26935015
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [High mobility group nucleosome binding protein 1 (HMGN1) induces activation of mouse BV2 microglia and upregulates their pro-inflammatory mediator expression by activating TLR4/MyD88/NF-κB p65/IKK-β signal pathway].
    Mao Y; Yu J; Yuan J; DA J; Yu F; Zha Y
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2024 Feb; 40(2):135-141. PubMed ID: 38284254
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HMGN1 and R848 Synergistically Activate Dendritic Cells Using Multiple Signaling Pathways.
    Alam MM; Yang D; Trivett A; Meyer TJ; Oppenheim JJ
    Front Immunol; 2018; 9():2982. PubMed ID: 30619338
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endotoxin-induced maturation of MyD88-deficient dendritic cells.
    Kaisho T; Takeuchi O; Kawai T; Hoshino K; Akira S
    J Immunol; 2001 May; 166(9):5688-94. PubMed ID: 11313410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin.
    Tewary P; Yang D; de la Rosa G; Li Y; Finn MW; Krensky AM; Clayberger C; Oppenheim JJ
    Blood; 2010 Nov; 116(18):3465-74. PubMed ID: 20660289
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rhamnogalacturonan II is a Toll-like receptor 4 agonist that inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells.
    Park SN; Noh KT; Jeong YI; Jung ID; Kang HK; Cha GS; Lee SJ; Seo JK; Kang DH; Hwang TH; Lee EK; Kwon B; Park YM
    Exp Mol Med; 2013 Feb; 45(2):e8. PubMed ID: 23392255
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Harnessing the alarmin HMGN1 for anticancer therapy.
    Yang D; Bustin M; Oppenheim JJ
    Immunotherapy; 2015; 7(11):1129-31. PubMed ID: 26567750
    [No Abstract]   [Full Text] [Related]  

  • 12. Intratumoral administration of TLR4 agonist absorbed into a cellular vector improves antitumor responses.
    Davis MB; Vasquez-Dunddel D; Fu J; Albesiano E; Pardoll D; Kim YJ
    Clin Cancer Res; 2011 Jun; 17(12):3984-92. PubMed ID: 21543518
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HMGN1 down-regulation in the diabetic kidney attenuates tubular cells injury and protects against renal inflammation via suppressing MCP-1 and KIM-1 expression through TLR4.
    Yu J; Da J; Yu F; Yuan J; Zha Y
    J Endocrinol Invest; 2024 Apr; 47(4):1015-1027. PubMed ID: 38409569
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex.
    Okamoto N; Mizote K; Honda H; Saeki A; Watanabe Y; Yamaguchi-Miyamoto T; Fukui R; Tanimura N; Motoi Y; Akashi-Takamura S; Kato T; Fujishita S; Kimura T; Ohto U; Shimizu T; Hirokawa T; Miyake K; Fukase K; Fujimoto Y; Nagai Y; Takatsu K
    J Biol Chem; 2017 Sep; 292(37):15378-15394. PubMed ID: 28754693
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A TLR4 agonist synergizes with dendritic cell-directed lentiviral vectors for inducing antigen-specific immune responses.
    Xiao L; Kim J; Lim M; Dai B; Yang L; Reed SG; Baltimore D; Wang P
    Vaccine; 2012 Mar; 30(15):2570-81. PubMed ID: 22314134
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activated apoptotic cells induce dendritic cell maturation via engagement of Toll-like receptor 4 (TLR4), dendritic cell-specific intercellular adhesion molecule 3 (ICAM-3)-grabbing nonintegrin (DC-SIGN), and β2 integrins.
    Pathak SK; Sköld AE; Mohanram V; Persson C; Johansson U; Spetz AL
    J Biol Chem; 2012 Apr; 287(17):13731-42. PubMed ID: 22396536
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation.
    Hu W; Jain A; Gao Y; Dozmorov IM; Mandraju R; Wakeland EK; Pasare C
    Proc Natl Acad Sci U S A; 2015 Nov; 112(45):13994-9. PubMed ID: 26508631
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endotoxin can induce MyD88-deficient dendritic cells to support T(h)2 cell differentiation.
    Kaisho T; Hoshino K; Iwabe T; Takeuchi O; Yasui T; Akira S
    Int Immunol; 2002 Jul; 14(7):695-700. PubMed ID: 12096028
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combining an Alarmin HMGN1 Peptide with PD-L1 Blockade Results in Robust Antitumor Effects with a Concomitant Increase of Stem-Like/Progenitor Exhausted CD8
    Chen CY; Ueha S; Ishiwata Y; Shichino S; Yokochi S; Yang D; Oppenheim JJ; Ogiwara H; Deshimaru S; Kanno Y; Aoki H; Ogawa T; Shibayama S; Matsushima K
    Cancer Immunol Res; 2021 Oct; 9(10):1214-1228. PubMed ID: 34344641
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alarmin-painted exosomes elicit persistent antitumor immunity in large established tumors in mice.
    Zuo B; Qi H; Lu Z; Chen L; Sun B; Yang R; Zhang Y; Liu Z; Gao X; You A; Wu L; Jing R; Zhou Q; Yin H
    Nat Commun; 2020 Apr; 11(1):1790. PubMed ID: 32286296
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.