154 related articles for article (PubMed ID: 22185844)
1. Marked change in the balance between CYP27A1 and CYP46A1 mediated elimination of cholesterol during differentiation of human neuronal cells.
Milagre I; Olin M; Nunes MJ; Moutinho M; Lövgren-Sandblom A; Gama MJ; Björkhem I; Rodrigues E
Neurochem Int; 2012 Jan; 60(2):192-8. PubMed ID: 22185844
[TBL] [Abstract][Full Text] [Related]
2. Neuronal differentiation alters the ratio of Sp transcription factors recruited to the CYP46A1 promoter.
Milagre I; Nunes MJ; Castro-Caldas M; Moutinho M; Gama MJ; Rodrigues E
J Neurochem; 2012 Jan; 120(2):220-9. PubMed ID: 22060190
[TBL] [Abstract][Full Text] [Related]
3. Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination.
Milagre I; Nunes MJ; Moutinho M; Rivera I; Fuso A; Scarpa S; Gama MJ; Rodrigues E
J Alzheimers Dis; 2010; 22(4):1209-21. PubMed ID: 20930312
[TBL] [Abstract][Full Text] [Related]
4. Differential expression of cholesterol hydroxylases in Alzheimer's disease.
Brown J; Theisler C; Silberman S; Magnuson D; Gottardi-Littell N; Lee JM; Yager D; Crowley J; Sambamurti K; Rahman MM; Reiss AB; Eckman CB; Wolozin B
J Biol Chem; 2004 Aug; 279(33):34674-81. PubMed ID: 15148325
[TBL] [Abstract][Full Text] [Related]
5. Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma.
Han M; Wang S; Yang N; Wang X; Zhao W; Saed HS; Daubon T; Huang B; Chen A; Li G; Miletic H; Thorsen F; Bjerkvig R; Li X; Wang J
EMBO Mol Med; 2020 Jan; 12(1):e10924. PubMed ID: 31777202
[TBL] [Abstract][Full Text] [Related]
6. Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum.
Mast N; Anderson KW; Lin JB; Li Y; Turko IV; Tatsuoka C; Bjorkhem I; Pikuleva IA
J Biol Chem; 2017 Mar; 292(12):4913-4924. PubMed ID: 28190002
[TBL] [Abstract][Full Text] [Related]
7. Oxysterols as biomarkers in neurodegenerative diseases.
Leoni V; Caccia C
Chem Phys Lipids; 2011 Sep; 164(6):515-24. PubMed ID: 21515244
[TBL] [Abstract][Full Text] [Related]
8. Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes.
Ohyama Y; Meaney S; Heverin M; Ekström L; Brafman A; Shafir M; Andersson U; Olin M; Eggertsen G; Diczfalusy U; Feinstein E; Björkhem I
J Biol Chem; 2006 Feb; 281(7):3810-20. PubMed ID: 16321981
[TBL] [Abstract][Full Text] [Related]
9. Quantification of cholesterol-metabolizing P450s CYP27A1 and CYP46A1 in neural tissues reveals a lack of enzyme-product correlations in human retina but not human brain.
Liao WL; Heo GY; Dodder NG; Reem RE; Mast N; Huang S; Dipatre PL; Turko IV; Pikuleva IA
J Proteome Res; 2011 Jan; 10(1):241-8. PubMed ID: 21049985
[TBL] [Abstract][Full Text] [Related]
10. Transcriptional regulation of the human CYP46A1 brain-specific expression by Sp transcription factors.
Milagre I; Nunes MJ; Gama MJ; Silva RF; Pascussi JM; Lechner MC; Rodrigues E
J Neurochem; 2008 Jul; 106(2):835-49. PubMed ID: 18445135
[TBL] [Abstract][Full Text] [Related]
11. CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington's disease.
Boussicault L; Alves S; Lamazière A; Planques A; Heck N; Moumné L; Despres G; Bolte S; Hu A; Pagès C; Galvan L; Piguet F; Aubourg P; Cartier N; Caboche J; Betuing S
Brain; 2016 Mar; 139(Pt 3):953-70. PubMed ID: 26912634
[TBL] [Abstract][Full Text] [Related]
12. Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling.
Gilardi F; Viviani B; Galmozzi A; Boraso M; Bartesaghi S; Torri A; Caruso D; Crestani M; Marinovich M; de Fabiani E
Neuroscience; 2009 Dec; 164(2):530-40. PubMed ID: 19665519
[TBL] [Abstract][Full Text] [Related]
13. Cholesterol-metabolizing cytochromes P450.
Pikuleva IA
Drug Metab Dispos; 2006 Apr; 34(4):513-20. PubMed ID: 16434543
[TBL] [Abstract][Full Text] [Related]
14. CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease.
Djelti F; Braudeau J; Hudry E; Dhenain M; Varin J; Bièche I; Marquer C; Chali F; Ayciriex S; Auzeil N; Alves S; Langui D; Potier MC; Laprevote O; Vidaud M; Duyckaerts C; Miles R; Aubourg P; Cartier N
Brain; 2015 Aug; 138(Pt 8):2383-98. PubMed ID: 26141492
[TBL] [Abstract][Full Text] [Related]
15. 24S-hydroxycholesterol and cholesterol-24S-hydroxylase (CYP46A1) in the retina: from cholesterol homeostasis to pathophysiology of glaucoma.
Fourgeux C; Bron A; Acar N; Creuzot-Garcher C; Bretillon L
Chem Phys Lipids; 2011 Sep; 164(6):496-9. PubMed ID: 21531213
[TBL] [Abstract][Full Text] [Related]
16. Okadaic acid inhibits the trichostatin A-mediated increase of human CYP46A1 neuronal expression in a ERK1/2-Sp3-dependent pathway.
Nunes MJ; Moutinho M; Milagre I; Gama MJ; Rodrigues E
J Lipid Res; 2012 Sep; 53(9):1910-9. PubMed ID: 22693257
[TBL] [Abstract][Full Text] [Related]
17. Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retina.
Bretillon L; Diczfalusy U; Björkhem I; Maire MA; Martine L; Joffre C; Acar N; Bron A; Creuzot-Garcher C
Curr Eye Res; 2007 Apr; 32(4):361-6. PubMed ID: 17453958
[TBL] [Abstract][Full Text] [Related]
18. Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors.
Shafaati M; O'Driscoll R; Björkhem I; Meaney S
Biochem Biophys Res Commun; 2009 Jan; 378(4):689-94. PubMed ID: 19059217
[TBL] [Abstract][Full Text] [Related]
19. Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover.
Lund EG; Xie C; Kotti T; Turley SD; Dietschy JM; Russell DW
J Biol Chem; 2003 Jun; 278(25):22980-8. PubMed ID: 12686551
[TBL] [Abstract][Full Text] [Related]
20. The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivo.
Shafaati M; Mast N; Beck O; Nayef R; Heo GY; Björkhem-Bergman L; Lütjohann D; Björkhem I; Pikuleva IA
J Lipid Res; 2010 Feb; 51(2):318-23. PubMed ID: 19474457
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
