BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 22186884)

  • 1. Anti-tumor activity and mechanism of action for a cyanoaziridine-derivative, AMP423.
    Dorr RT; Wisner L; Samulitis BK; Landowski TH; Remers WA
    Cancer Chemother Pharmacol; 2012 Apr; 69(4):1039-49. PubMed ID: 22186884
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antiproliferative and antitumor activity of the 2-cyanoaziridine compound imexon on tumor cell lines and fresh tumor cells in vitro.
    Hersh EM; Gschwind CR; Taylor CW; Dorr RT; Taetle R; Salmon SE
    J Natl Cancer Inst; 1992 Aug; 84(16):1238-44. PubMed ID: 1640482
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemistry and pharmacology of imexon and related cyanoaziridines.
    Remers WA; Dorr RT
    Curr Med Chem; 2012; 19(33):5745-53. PubMed ID: 22998528
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Preclinical antitumor activity, pharmacokinetics and pharmacodynamics of imexon in mice.
    Pourpak A; Meyers RO; Samulitis BK; Sherry Chow HH; Kepler CY; Raymond MA; Hersh E; Dorr RT
    Anticancer Drugs; 2006 Nov; 17(10):1179-84. PubMed ID: 17075317
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel antitumor 2-cyanoaziridine-1-carboxamides.
    Iyengar BS; Dorr RT; Alberts DS; Hersh EM; Salmon SE; Remers WA
    J Med Chem; 1999 Feb; 42(3):510-4. PubMed ID: 9986721
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Correlates of imexon sensitivity in human multiple myeloma cell lines.
    Samulitis BK; Landowski TH; Dorr RT
    Leuk Lymphoma; 2006 Jan; 47(1):97-109. PubMed ID: 16321833
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemical basis for the biological activity of imexon and related cyanoaziridines.
    Iyengar BS; Dorr RT; Remers WA
    J Med Chem; 2004 Jan; 47(1):218-23. PubMed ID: 14695835
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of mitochondrial changes in myeloma cells by imexon.
    Dvorakova K; Waltmire CN; Payne CM; Tome ME; Briehl MM; Dorr RT
    Blood; 2001 Jun; 97(11):3544-51. PubMed ID: 11369649
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Imexon-induced apoptosis in multiple myeloma tumor cells is caspase-8 dependent.
    Evens AM; Prachand S; Shi B; Paniaqua M; Gordon LI; Gartenhaus RB
    Clin Cancer Res; 2004 Feb; 10(4):1481-91. PubMed ID: 14977852
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of oxidative stress and apoptosis in myeloma cells by the aziridine-containing agent imexon.
    Dvorakova K; Payne CM; Tome ME; Briehl MM; McClure T; Dorr RT
    Biochem Pharmacol; 2000 Sep; 60(6):749-58. PubMed ID: 10930529
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Imexon-based combination chemotherapy in A375 human melanoma and RPMI 8226 human myeloma cell lines.
    Scott J; Dorr RT; Samulitis B; Landowski TH
    Cancer Chemother Pharmacol; 2007 May; 59(6):749-57. PubMed ID: 17333195
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interaction of dacarbazine and imexon, in vitro and in vivo, in human A375 melanoma cells.
    Samulitis BK; Dorr RT; Chow HH
    Anticancer Res; 2011 Sep; 31(9):2781-5. PubMed ID: 21868520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combined phase I/II study of imexon (AOP99.0001) for treatment of relapsed or refractory multiple myeloma.
    Moehler TM; Feneberg R; Ho AD; Golenkov AK; Ludwig H; Kropff M; Khuageva NK; Hajda J; von Broen I; Goldschmidt H
    Anticancer Drugs; 2010 Aug; 21(7):708-15. PubMed ID: 20571355
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma.
    Wang S; Yang H; Su M; Lian F; Cong Z; Wei R; Zhou Y; Li X; Zheng X; Li C; Fu X; Han X; Shi Q; Li C; Zhang N; Geng M; Liu H; Li J; Huang X; Wang J
    Eur J Med Chem; 2021 Oct; 222():113592. PubMed ID: 34147909
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of apoptosis and cell cycle arrest by imexon in human pancreatic cancer cell lines.
    Dorr RT; Raymond MA; Landowski TH; Roman NO; Fukushima S
    Int J Gastrointest Cancer; 2005; 36(1):15-28. PubMed ID: 16227632
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pterostilbene Inhibits Human Multiple Myeloma Cells via ERK1/2 and JNK Pathway In Vitro and In Vivo.
    Xie B; Xu Z; Hu L; Chen G; Wei R; Yang G; Li B; Chang G; Sun X; Wu H; Zhang Y; Dai B; Tao Y; Shi J; Zhu W
    Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27869675
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies.
    Deckert J; Wetzel MC; Bartle LM; Skaletskaya A; Goldmacher VS; Vallée F; Zhou-Liu Q; Ferrari P; Pouzieux S; Lahoute C; Dumontet C; Plesa A; Chiron M; Lejeune P; Chittenden T; Park PU; Blanc V
    Clin Cancer Res; 2014 Sep; 20(17):4574-83. PubMed ID: 24987056
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Preclinical pharmacokinetics and antitumor activity of imexon.
    Dorr RT; Liddil JD; Klein MK; Hersh EM
    Invest New Drugs; 1995; 13(2):113-6. PubMed ID: 8617572
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma.
    Jakubikova J; Cervi D; Ooi M; Kim K; Nahar S; Klippel S; Cholujova D; Leiba M; Daley JF; Delmore J; Negri J; Blotta S; McMillin DW; Hideshima T; Richardson PG; Sedlak J; Anderson KC; Mitsiades CS
    Haematologica; 2011 Aug; 96(8):1170-9. PubMed ID: 21712538
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular and cellular characterization of imexon-resistant RPMI8226/I myeloma cells.
    Dvorakova K; Payne CM; Tome ME; Briehl MM; Vasquez MA; Waltmire CN; Coon A; Dorr RT
    Mol Cancer Ther; 2002 Jan; 1(3):185-95. PubMed ID: 12467213
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.