235 related articles for article (PubMed ID: 22188814)
1. Cooperation between c-Met and focal adhesion kinase family members in medulloblastoma and implications for therapy.
Guessous F; Yang Y; Johnson E; Marcinkiewicz L; Smith M; Zhang Y; Kofman A; Schiff D; Christensen J; Abounader R
Mol Cancer Ther; 2012 Feb; 11(2):288-97. PubMed ID: 22188814
[TBL] [Abstract][Full Text] [Related]
2. Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness.
Behmoaram E; Bijian K; Jie S; Xu Y; Darnel A; Bismar TA; Alaoui-Jamali MA
Am J Pathol; 2008 Nov; 173(5):1540-50. PubMed ID: 18832579
[TBL] [Abstract][Full Text] [Related]
3. Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma.
Kanteti R; Mirzapoiazova T; Riehm JJ; Dhanasingh I; Mambetsariev B; Wang J; Kulkarni P; Kaushik G; Seshacharyulu P; Ponnusamy MP; Kindler HL; Nasser MW; Batra SK; Salgia R
Cancer Biol Ther; 2018 Apr; 19(4):316-327. PubMed ID: 29303405
[TBL] [Abstract][Full Text] [Related]
4. B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading.
Tse KW; Dang-Lawson M; Lee RL; Vong D; Bulic A; Buckbinder L; Gold MR
J Biol Chem; 2009 Aug; 284(34):22865-77. PubMed ID: 19561089
[TBL] [Abstract][Full Text] [Related]
5. The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy.
Li Y; Lal B; Kwon S; Fan X; Saldanha U; Reznik TE; Kuchner EB; Eberhart C; Laterra J; Abounader R
Cancer Res; 2005 Oct; 65(20):9355-62. PubMed ID: 16230398
[TBL] [Abstract][Full Text] [Related]
6. Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity.
Fan H; Guan JL
J Biol Chem; 2011 May; 286(21):18573-82. PubMed ID: 21471206
[TBL] [Abstract][Full Text] [Related]
7. Small molecule inhibitors of the Pyk2 and FAK kinases modulate chemoattractant-induced migration, adhesion and Akt activation in follicular and marginal zone B cells.
Tse KW; Lin KB; Dang-Lawson M; Guzman-Perez A; Aspnes GE; Buckbinder L; Gold MR
Cell Immunol; 2012; 275(1-2):47-54. PubMed ID: 22507871
[TBL] [Abstract][Full Text] [Related]
8. Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia.
Xu CS; Wang ZF; Huang XD; Dai LM; Cao CJ; Li ZQ
J Transl Med; 2015 Mar; 13():95. PubMed ID: 25889845
[TBL] [Abstract][Full Text] [Related]
9. Met tyrosine kinase inhibitor, PF-2341066, suppresses growth and invasion of nasopharyngeal carcinoma.
Zhao Y; Zhang J; Tian Y; Xue C; Hu Z; Zhang L
Drug Des Devel Ther; 2015; 9():4897-907. PubMed ID: 26345996
[TBL] [Abstract][Full Text] [Related]
10. Pyk2 promotes tumor progression in multiple myeloma.
Zhang Y; Moschetta M; Huynh D; Tai YT; Zhang Y; Zhang W; Mishima Y; Ring JE; Tam WF; Xu Q; Maiso P; Reagan M; Sahin I; Sacco A; Manier S; Aljawai Y; Glavey S; Munshi NC; Anderson KC; Pachter J; Roccaro AM; Ghobrial IM
Blood; 2014 Oct; 124(17):2675-86. PubMed ID: 25217697
[TBL] [Abstract][Full Text] [Related]
11. Matriptase is required for the active form of hepatocyte growth factor induced Met, focal adhesion kinase and protein kinase B activation on neural stem/progenitor cell motility.
Fang JD; Lee SL
Biochim Biophys Acta; 2014 Jul; 1843(7):1285-94. PubMed ID: 24685580
[TBL] [Abstract][Full Text] [Related]
12. Cardiac fibroblasts require focal adhesion kinase for normal proliferation and migration.
Manso AM; Kang SM; Plotnikov SV; Thievessen I; Oh J; Beggs HE; Ross RS
Am J Physiol Heart Circ Physiol; 2009 Mar; 296(3):H627-38. PubMed ID: 19136609
[TBL] [Abstract][Full Text] [Related]
13. PYK2 negatively regulates the Hippo pathway in TNBC by stabilizing TAZ protein.
Kedan A; Verma N; Saroha A; Shreberk-Shaked M; Müller AK; Nair NU; Lev S
Cell Death Dis; 2018 Sep; 9(10):985. PubMed ID: 30250159
[TBL] [Abstract][Full Text] [Related]
14. CT-707, a Novel FAK Inhibitor, Synergizes with Cabozantinib to Suppress Hepatocellular Carcinoma by Blocking Cabozantinib-Induced FAK Activation.
Wang DD; Chen Y; Chen ZB; Yan FJ; Dai XY; Ying MD; Cao J; Ma J; Luo PH; Han YX; Peng Y; Sun YH; Zhang H; He QJ; Yang B; Zhu H
Mol Cancer Ther; 2016 Dec; 15(12):2916-2925. PubMed ID: 27638856
[TBL] [Abstract][Full Text] [Related]
15. An orally available small-molecule inhibitor of c-Met, PF-2341066, reduces tumor burden and metastasis in a preclinical model of ovarian cancer metastasis.
Zillhardt M; Christensen JG; Lengyel E
Neoplasia; 2010 Jan; 12(1):1-10. PubMed ID: 20072648
[TBL] [Abstract][Full Text] [Related]
16. Therapeutic Potential of Focal Adhesion Kinase Inhibition in Small Cell Lung Cancer.
Aboubakar Nana F; Lecocq M; Ladjemi MZ; Detry B; Dupasquier S; Feron O; Massion PP; Sibille Y; Pilette C; Ocak S
Mol Cancer Ther; 2019 Jan; 18(1):17-27. PubMed ID: 30352800
[TBL] [Abstract][Full Text] [Related]
17. Proline-rich tyrosine kinase 2 (Pyk2) regulates IGF-I-induced cell motility and invasion of urothelial carcinoma cells.
Genua M; Xu SQ; Buraschi S; Peiper SC; Gomella LG; Belfiore A; Iozzo RV; Morrione A
PLoS One; 2012; 7(6):e40148. PubMed ID: 22859931
[TBL] [Abstract][Full Text] [Related]
18. Pharmacological Inhibition of FAK-Pyk2 Pathway Protects Against Organ Damage and Prolongs the Survival of Septic Mice.
Alves GF; Aimaretti E; Einaudi G; Mastrocola R; de Oliveira JG; Collotta D; Porchietto E; Aragno M; Cifani C; Sordi R; Thiemermann C; Fernandes D; Collino M
Front Immunol; 2022; 13():837180. PubMed ID: 35178052
[TBL] [Abstract][Full Text] [Related]
19. HGF and c-Met participate in paracrine tumorigenic pathways in head and neck squamous cell cancer.
Knowles LM; Stabile LP; Egloff AM; Rothstein ME; Thomas SM; Gubish CT; Lerner EC; Seethala RR; Suzuki S; Quesnelle KM; Morgan S; Ferris RL; Grandis JR; Siegfried JM
Clin Cancer Res; 2009 Jun; 15(11):3740-50. PubMed ID: 19470725
[TBL] [Abstract][Full Text] [Related]
20. Selective targeting of FAK-Pyk2 axis by alpha-naphthoflavone abrogates doxorubicin resistance in breast cancer cells.
Datta A; Bhasin N; Kim H; Ranjan M; Rider B; Abd Elmageed ZY; Mondal D; Agrawal KC; Abdel-Mageed AB
Cancer Lett; 2015 Jun; 362(1):25-35. PubMed ID: 25796439
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
