BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 22192590)

  • 1. Design and synthesis of small molecular dual inhibitor of falcipain-2 and dihydrofolate reductase as antimalarial agent.
    Huang H; Lu W; Li X; Cong X; Ma H; Liu X; Zhang Y; Che P; Ma R; Li H; Shen X; Jiang H; Huang J; Zhu J
    Bioorg Med Chem Lett; 2012 Jan; 22(2):958-62. PubMed ID: 22192590
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of new antimalarial agents: Second-generation dual inhibitors against FP-2 and PfDHFR via fragments assembely.
    Chen W; Huang Z; Wang W; Mao F; Guan L; Tang Y; Jiang H; Li J; Huang J; Jiang L; Zhu J
    Bioorg Med Chem; 2017 Dec; 25(24):6467-6478. PubMed ID: 29111368
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Falcipain inhibitors as potential therapeutics for resistant strains of malaria: a patent review.
    Mane UR; Gupta RC; Nadkarni SS; Giridhar RR; Naik PP; Yadav MR
    Expert Opin Ther Pat; 2013 Feb; 23(2):165-87. PubMed ID: 23228154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pyrido[1,2-a]pyrimidin-4-ones as antiplasmodial falcipain-2 inhibitors.
    Mane UR; Li H; Huang J; Gupta RC; Nadkarni SS; Giridhar R; Naik PP; Yadav MR
    Bioorg Med Chem; 2012 Nov; 20(21):6296-304. PubMed ID: 23040894
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of novel class of falcipain-2 inhibitors as potential antimalarial agents.
    Chakka SK; Kalamuddin M; Sundararaman S; Wei L; Mundra S; Mahesh R; Malhotra P; Mohmmed A; Kotra LP
    Bioorg Med Chem; 2015 May; 23(9):2221-40. PubMed ID: 25840796
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of new antimalarial phenylurenyl chalcone derivatives.
    Domínguez JN; León C; Rodrigues J; Gamboa de Domínguez N; Gut J; Rosenthal PJ
    J Med Chem; 2005 May; 48(10):3654-8. PubMed ID: 15887974
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ligand-based virtual screening and in silico design of new antimalarial compounds using nonstochastic and stochastic total and atom-type quadratic maps.
    Marrero-Ponce Y; Iyarreta-Veitía M; Montero-Torres A; Romero-Zaldivar C; Brandt CA; Avila PE; Kirchgatter K; Machado Y
    J Chem Inf Model; 2005; 45(4):1082-100. PubMed ID: 16045304
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of antimalarial leads with dual falcipain-2 and falcipain-3 inhibitory activity.
    Rana D; Kalamuddin M; Sundriyal S; Jaiswal V; Sharma G; Das Sarma K; Sijwali PS; Mohmmed A; Malhotra P; Mahindroo N
    Bioorg Med Chem; 2020 Jan; 28(1):115155. PubMed ID: 31744777
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of diverse natural products as falcipain-2 inhibitors through structure-based virtual screening.
    Wang L; Zhang S; Zhu J; Zhu L; Liu X; Shan L; Huang J; Zhang W; Li H
    Bioorg Med Chem Lett; 2014 Mar; 24(5):1261-4. PubMed ID: 24530004
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and molecular modeling studies of derivatives of a highly potent peptidomimetic vinyl ester as falcipain-2 inhibitors.
    Ettari R; Micale N; Grazioso G; Bova F; Schirmeister T; Grasso S; Zappalà M
    ChemMedChem; 2012 Sep; 7(9):1594-600. PubMed ID: 22753258
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of novel malarial cysteine protease inhibitors using structure-based virtual screening of a focused cysteine protease inhibitor library.
    Shah F; Mukherjee P; Gut J; Legac J; Rosenthal PJ; Tekwani BL; Avery MA
    J Chem Inf Model; 2011 Apr; 51(4):852-64. PubMed ID: 21428453
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and insight into the structure-activity relationships of chalcones as antimalarial agents.
    Tadigoppula N; Korthikunta V; Gupta S; Kancharla P; Khaliq T; Soni A; Srivastava RK; Srivastava K; Puri SK; Raju KS; Wahajuddin ; Sijwali PS; Kumar V; Mohammad IS
    J Med Chem; 2013 Jan; 56(1):31-45. PubMed ID: 23270565
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Computation-based virtual screening for designing novel antimalarial drugs by targeting falcipain-III: a structure-based drug designing approach.
    Kesharwani RK; Singh DV; Misra K
    J Vector Borne Dis; 2013; 50(2):93-102. PubMed ID: 23995310
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of sulfonylurea derivatives as novel antimalarials.
    León C; Rodrigues J; Gamboa de Domínguez N; Charris J; Gut J; Rosenthal PJ; Domínguez JN
    Eur J Med Chem; 2007 Jun; 42(6):735-42. PubMed ID: 17321641
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tetraoxane-pyrimidine nitrile hybrids as dual stage antimalarials.
    Oliveira R; Guedes RC; Meireles P; Albuquerque IS; Gonçalves LM; Pires E; Bronze MR; Gut J; Rosenthal PJ; Prudêncio M; Moreira R; O'Neill PM; Lopes F
    J Med Chem; 2014 Jun; 57(11):4916-23. PubMed ID: 24824551
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of gallinamide A analogues as potent falcipain inhibitors and antimalarials.
    Conroy T; Guo JT; Elias N; Cergol KM; Gut J; Legac J; Khatoon L; Liu Y; McGowan S; Rosenthal PJ; Hunt NH; Payne RJ
    J Med Chem; 2014 Dec; 57(24):10557-63. PubMed ID: 25412465
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents.
    Fattorusso C; Campiani G; Kukreja G; Persico M; Butini S; Romano MP; Altarelli M; Ros S; Brindisi M; Savini L; Novellino E; Nacci V; Fattorusso E; Parapini S; Basilico N; Taramelli D; Yardley V; Croft S; Borriello M; Gemma S
    J Med Chem; 2008 Mar; 51(5):1333-43. PubMed ID: 18278859
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antimalarial activity of Floxacrine (HOE 991) I. Studies on blood schizontocidal action of Floxacrine against Plasmodium berghei, P. vinckei and P. cynomolgi.
    Raether W; Fink E
    Ann Trop Med Parasitol; 1979 Dec; 73(6):505-26. PubMed ID: 120142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rational drug design approach for overcoming drug resistance: application to pyrimethamine resistance in malaria.
    McKie JH; Douglas KT; Chan C; Roser SA; Yates R; Read M; Hyde JE; Dascombe MJ; Yuthavong Y; Sirawaraporn W
    J Med Chem; 1998 Apr; 41(9):1367-70. PubMed ID: 9554869
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A prodomain peptide of Plasmodium falciparum cysteine protease (falcipain-2) inhibits malaria parasite development.
    Korde R; Bhardwaj A; Singh R; Srivastava A; Chauhan VS; Bhatnagar RK; Malhotra P
    J Med Chem; 2008 Jun; 51(11):3116-23. PubMed ID: 18461922
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.