These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 22194440)

  • 41. Rituximab and 17-allylamino-17-demethoxygeldanamycin induce synergistic apoptosis in B-cell chronic lymphocytic leukaemia.
    Johnson AJ; Wagner AJ; Cheney CM; Smith LL; Lucas DM; Guster SK; Grever MR; Lin TS; Byrd JC
    Br J Haematol; 2007 Dec; 139(5):837-44. PubMed ID: 17949452
    [TBL] [Abstract][Full Text] [Related]  

  • 42. HSP90 inhibitors induce desensitization of EGF receptor via p38 MAPK-mediated phosphorylation at Ser1046/1047 in human pancreatic cancer cells.
    Adachi S; Yasuda I; Nakashima M; Yamauchi T; Yamauchi J; Natsume H; Moriwaki H; Kozawa O
    Oncol Rep; 2010 Jun; 23(6):1709-14. PubMed ID: 20428829
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin.
    Bull EE; Dote H; Brady KJ; Burgan WE; Carter DJ; Cerra MA; Oswald KA; Hollingshead MG; Camphausen K; Tofilon PJ
    Clin Cancer Res; 2004 Dec; 10(23):8077-84. PubMed ID: 15585643
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma.
    Khaledian B; Taguchi A; Shin-Ya K; Kondo-Ida L; Kagaya N; Suzuki M; Kajino T; Yamaguchi T; Shimada Y; Takahashi T
    Cancer Sci; 2021 Mar; 112(3):1225-1234. PubMed ID: 33370472
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Gene expression-based chemical genomics identifies heat-shock protein 90 inhibitors as potential therapeutic drugs in cholangiocarcinoma.
    Chen MH; Lin KJ; Yang WL; Kao YW; Chen TW; Chao SC; Chang PM; Liu CY; Tzeng CH; Chao Y; Chen MH; Yeh CN; Huang CY
    Cancer; 2013 Jan; 119(2):293-303. PubMed ID: 22810956
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Schedule-dependent synergy between the heat shock protein 90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin and doxorubicin restores apoptosis to p53-mutant lymphoma cell lines.
    Robles AI; Wright MH; Gandhi B; Feis SS; Hanigan CL; Wiestner A; Varticovski L
    Clin Cancer Res; 2006 Nov; 12(21):6547-56. PubMed ID: 17085670
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Targeting heat shock protein 90 in pancreatic cancer impairs insulin-like growth factor-I receptor signaling, disrupts an interleukin-6/signal-transducer and activator of transcription 3/hypoxia-inducible factor-1alpha autocrine loop, and reduces orthotopic tumor growth.
    Lang SA; Moser C; Gaumann A; Klein D; Glockzin G; Popp FC; Dahlke MH; Piso P; Schlitt HJ; Geissler EK; Stoeltzing O
    Clin Cancer Res; 2007 Nov; 13(21):6459-68. PubMed ID: 17975158
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Sulforaphane potentiates the efficacy of 17-allylamino 17-demethoxygeldanamycin against pancreatic cancer through enhanced abrogation of Hsp90 chaperone function.
    Li Y; Zhang T; Schwartz SJ; Sun D
    Nutr Cancer; 2011; 63(7):1151-9. PubMed ID: 21875325
    [TBL] [Abstract][Full Text] [Related]  

  • 49. 17-DMAG induces heat shock protein 90 functional impairment in human bladder cancer cells: knocking down the hallmark traits of malignancy.
    Karkoulis PK; Stravopodis DJ; Voutsinas GE
    Tumour Biol; 2016 May; 37(5):6861-73. PubMed ID: 26662567
    [TBL] [Abstract][Full Text] [Related]  

  • 50. HSP90 is a promising target in gemcitabine and 5-fluorouracil resistant pancreatic cancer.
    Ghadban T; Dibbern JL; Reeh M; Miro JT; Tsui TY; Wellner U; Izbicki JR; Güngör C; Vashist YK
    Apoptosis; 2017 Mar; 22(3):369-380. PubMed ID: 27878398
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Synthesis and biological evaluation of geldanamycin analogs against human cancer cells.
    Li YP; Chen JJ; Shen JJ; Cui J; Wu LZ; Wang Z; Li ZR
    Cancer Chemother Pharmacol; 2015 Apr; 75(4):773-82. PubMed ID: 25681003
    [TBL] [Abstract][Full Text] [Related]  

  • 52. ZAP-70 is a novel conditional heat shock protein 90 (Hsp90) client: inhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukemia.
    Castro JE; Prada CE; Loria O; Kamal A; Chen L; Burrows FJ; Kipps TJ
    Blood; 2005 Oct; 106(7):2506-12. PubMed ID: 15972449
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Associations of HSP90 client proteins in human breast cancer.
    Shipp C; Watson K; Jones GL
    Anticancer Res; 2011 Jun; 31(6):2095-101. PubMed ID: 21737627
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Targeting HSP90 Gene Expression with 17-DMAG Nanoparticles in Breast Cancer Cells.
    Mellatyar H; Talaei S; Nejati-Koshki K; Akbarzadeh A
    Asian Pac J Cancer Prev; 2016; 17(5):2453-7. PubMed ID: 27268613
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Blind cavefish and heat shock protein chaperones: a novel role for hsp90alpha in lens apoptosis.
    Hooven TA; Yamamoto Y; Jeffery WR
    Int J Dev Biol; 2004; 48(8-9):731-8. PubMed ID: 15558465
    [TBL] [Abstract][Full Text] [Related]  

  • 56. HSP90 protects apoptotic cleavage of vimentin in geldanamycin-induced apoptosis.
    Zhang MH; Lee JS; Kim HJ; Jin DI; Kim JI; Lee KJ; Seo JS
    Mol Cell Biochem; 2006 Jan; 281(1-2):111-21. PubMed ID: 16328963
    [TBL] [Abstract][Full Text] [Related]  

  • 57. [Enhancement of HER-2 degradation by carbamazepine in breast cancer SKBR-3 cell line].
    Meng QW; Zhao CH; Xi YH; Cai L; Sun LC; Sui GJ
    Zhonghua Zhong Liu Za Zhi; 2006 Jul; 28(7):503-6. PubMed ID: 17147113
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants.
    Prince TL; Kijima T; Tatokoro M; Lee S; Tsutsumi S; Yim K; Rivas C; Alarcon S; Schwartz H; Khamit-Kush K; Scroggins BT; Beebe K; Trepel JB; Neckers L
    PLoS One; 2015; 10(10):e0141786. PubMed ID: 26517842
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Role for NAD(P)H:quinone oxidoreductase 1 and manganese-dependent superoxide dismutase in 17-(allylamino)-17-demethoxygeldanamycin-induced heat shock protein 90 inhibition in pancreatic cancer cells.
    Siegel D; Shieh B; Yan C; Kepa JK; Ross D
    J Pharmacol Exp Ther; 2011 Mar; 336(3):874-80. PubMed ID: 21156818
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Targeting heat shock protein 72 enhances Hsp90 inhibitor-induced apoptosis in myeloma.
    Davenport EL; Zeisig A; Aronson LI; Moore HE; Hockley S; Gonzalez D; Smith EM; Powers MV; Sharp SY; Workman P; Morgan GJ; Davies FE
    Leukemia; 2010 Oct; 24(10):1804-7. PubMed ID: 20703255
    [No Abstract]   [Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.