BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 22194691)

  • 1. Granzyme B inhibits vaccinia virus production through proteolytic cleavage of eukaryotic initiation factor 4 gamma 3.
    Marcet-Palacios M; Duggan BL; Shostak I; Barry M; Geskes T; Wilkins JA; Yanagiya A; Sonenberg N; Bleackley RC
    PLoS Pathog; 2011 Dec; 7(12):e1002447. PubMed ID: 22194691
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Granzyme B-mediated degradation of T-cell receptor zeta chain.
    Wieckowski E; Wang GQ; Gastman BR; Goldstein LA; Rabinowich H
    Cancer Res; 2002 Sep; 62(17):4884-9. PubMed ID: 12208735
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation.
    Sharif-Askari E; Alam A; Rhéaume E; Beresford PJ; Scotto C; Sharma K; Lee D; DeWolf WE; Nuttall ME; Lieberman J; Sékaly RP
    EMBO J; 2001 Jun; 20(12):3101-13. PubMed ID: 11406587
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytotoxic T lymphocyte-assisted suicide. Caspase 3 activation is primarily the result of the direct action of granzyme B.
    Atkinson EA; Barry M; Darmon AJ; Shostak I; Turner PC; Moyer RW; Bleackley RC
    J Biol Chem; 1998 Aug; 273(33):21261-6. PubMed ID: 9694885
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Granule-mediated killing: pathways for granzyme B-initiated apoptosis.
    Talanian RV; Yang X; Turbov J; Seth P; Ghayur T; Casiano CA; Orth K; Froelich CJ
    J Exp Med; 1997 Oct; 186(8):1323-31. PubMed ID: 9334372
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis.
    Medema JP; Toes RE; Scaffidi C; Zheng TS; Flavell RA; Melief CJ; Peter ME; Offringa R; Krammer PH
    Eur J Immunol; 1997 Dec; 27(12):3492-8. PubMed ID: 9464839
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cleavage of Notch1 by granzyme B disables its transcriptional activity.
    van Tetering G; Bovenschen N; Meeldijk J; van Diest PJ; Vooijs M
    Biochem J; 2011 Jul; 437(2):313-22. PubMed ID: 21548883
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteasome inhibitors and immunosuppressive drugs promote the cleavage of eIF4GI and eIF4GII by caspase-8-independent mechanisms in Jurkat T cell lines.
    Morley SJ; Pain VM
    FEBS Lett; 2001 Aug; 503(2-3):206-12. PubMed ID: 11513883
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Direct cleavage of ROCK II by granzyme B induces target cell membrane blebbing in a caspase-independent manner.
    Sebbagh M; Hamelin J; Bertoglio J; Solary E; Bréard J
    J Exp Med; 2005 Feb; 201(3):465-71. PubMed ID: 15699075
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis.
    Metkar SS; Wang B; Ebbs ML; Kim JH; Lee YJ; Raja SM; Froelich CJ
    J Cell Biol; 2003 Mar; 160(6):875-85. PubMed ID: 12629051
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells.
    Marissen WE; Lloyd RE
    Mol Cell Biol; 1998 Dec; 18(12):7565-74. PubMed ID: 9819442
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
    Han J; Goldstein LA; Gastman BR; Rabinovitz A; Rabinowich H
    J Biol Chem; 2005 Apr; 280(16):16383-92. PubMed ID: 15713684
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Caspase-dependent inhibition of mousepox replication by gzmB.
    Pardo J; Gálvez EM; Koskinen A; Simon MM; Lobigs M; Regner M; Müllbacher A
    PLoS One; 2009 Oct; 4(10):e7512. PubMed ID: 19838298
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Apoptosis induced by granzyme B-glycosaminoglycan complexes: implications for granule-mediated apoptosis in vivo.
    Galvin JP; Spaeny-Dekking LH; Wang B; Seth P; Hack CE; Froelich CJ
    J Immunol; 1999 May; 162(9):5345-50. PubMed ID: 10228010
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B.
    Adrain C; Murphy BM; Martin SJ
    J Biol Chem; 2005 Feb; 280(6):4663-73. PubMed ID: 15569669
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B.
    Afonina IS; Cullen SP; Martin SJ
    Immunol Rev; 2010 May; 235(1):105-16. PubMed ID: 20536558
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Caspase-3 is necessary and sufficient for cleavage of protein synthesis eukaryotic initiation factor 4G during apoptosis.
    Bushell M; McKendrick L; Jänicke RU; Clemens MJ; Morley SJ
    FEBS Lett; 1999 May; 451(3):332-6. PubMed ID: 10371215
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Adenovirus L4-100K assembly protein is a granzyme B substrate that potently inhibits granzyme B-mediated cell death.
    Andrade F; Bull HG; Thornberry NA; Ketner GW; Casciola-Rosen LA; Rosen A
    Immunity; 2001 Jun; 14(6):751-61. PubMed ID: 11420045
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Granzyme B encoded by the commonly occurring human RAH allele retains pro-apoptotic activity.
    Sun J; Bird CH; Thia KY; Matthews AY; Trapani JA; Bird PI
    J Biol Chem; 2004 Apr; 279(17):16907-11. PubMed ID: 14752093
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanistic studies of a novel human fusion toxin composed of vascular endothelial growth factor (VEGF)121 and the serine protease granzyme B: directed apoptotic events in vascular endothelial cells.
    Liu Y; Cheung LH; Thorpe P; Rosenblum MG
    Mol Cancer Ther; 2003 Oct; 2(10):949-59. PubMed ID: 14578460
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.