BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

263 related articles for article (PubMed ID: 22196480)

  • 1. Design of triazole-stapled BCL9 α-helical peptides to target the β-catenin/B-cell CLL/lymphoma 9 (BCL9) protein-protein interaction.
    Kawamoto SA; Coleska A; Ran X; Yi H; Yang CY; Wang S
    J Med Chem; 2012 Feb; 55(3):1137-46. PubMed ID: 22196480
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Decoding the dynamics of BCL9 triazole stapled peptide.
    Gaikwad V; Choudhury AR; Chakrabarti R
    Biophys Chem; 2024 Apr; 307():107197. PubMed ID: 38335808
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of β-catenin/B cell lymphoma 9 protein-protein interaction using α-helix-mimicking sulfono-γ-AApeptide inhibitors.
    Sang P; Zhang M; Shi Y; Li C; Abdulkadir S; Li Q; Ji H; Cai J
    Proc Natl Acad Sci U S A; 2019 May; 116(22):10757-10762. PubMed ID: 31088961
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling.
    Takada K; Zhu D; Bird GH; Sukhdeo K; Zhao JJ; Mani M; Lemieux M; Carrasco DE; Ryan J; Horst D; Fulciniti M; Munshi NC; Xu W; Kung AL; Shivdasani RA; Walensky LD; Carrasco DR
    Sci Transl Med; 2012 Aug; 4(148):148ra117. PubMed ID: 22914623
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analysis of the interaction of BCL9 with beta-catenin and development of fluorescence polarization and surface plasmon resonance binding assays for this interaction.
    Kawamoto SA; Thompson AD; Coleska A; Nikolovska-Coleska Z; Yi H; Wang S
    Biochemistry; 2009 Oct; 48(40):9534-41. PubMed ID: 19715304
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of a beta-catenin/BCL9/Tcf4 complex.
    Sampietro J; Dahlberg CL; Cho US; Hinds TR; Kimelman D; Xu W
    Mol Cell; 2006 Oct; 24(2):293-300. PubMed ID: 17052462
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure-Based Optimization of Small-Molecule Inhibitors for the β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction.
    Zhang M; Wang Z; Zhang Y; Guo W; Ji H
    J Med Chem; 2018 Apr; 61(7):2989-3007. PubMed ID: 29566337
    [TBL] [Abstract][Full Text] [Related]  

  • 8. AlphaScreen selectivity assay for β-catenin/B-cell lymphoma 9 inhibitors.
    Zhang M; Wisniewski JA; Ji H
    Anal Biochem; 2015 Jan; 469():43-53. PubMed ID: 25312469
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cell-type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin.
    Sustmann C; Flach H; Ebert H; Eastman Q; Grosschedl R
    Mol Cell Biol; 2008 May; 28(10):3526-37. PubMed ID: 18347063
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of 2-(3-(3-Carbamoylpiperidin-1-yl)phenoxy)acetic Acid Derivatives as Novel Small-Molecule Inhibitors of the β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction.
    Wang Z; Zhang M; Luo W; Zhang Y; Ji H
    J Med Chem; 2021 May; 64(9):5886-5904. PubMed ID: 33902288
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Recent advances in β-catenin/BCL9 protein-protein interaction inhibitors.
    Zhang H; Bao Y; Liu C; Li J; Zhu D; Zhang Q
    Future Med Chem; 2021 May; 13(10):927-940. PubMed ID: 33849283
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Click-chemistry-derived triazole ligands of arginine-glycine-aspartate (RGD) integrins with a broad capacity to inhibit adhesion of melanoma cells and both in vitro and in vivo angiogenesis.
    Trabocchi A; Menchi G; Cini N; Bianchini F; Raspanti S; Bottoncetti A; Pupi A; Calorini L; Guarna A
    J Med Chem; 2010 Oct; 53(19):7119-28. PubMed ID: 20809642
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BCL9 Upregulation in Adrenocortical Carcinoma: A Novel Wnt/β-Catenin Activating Event Driving Adrenocortical Malignancy.
    Brown TC; Nicolson NG; Korah R; Carling T
    J Am Coll Surg; 2018 Jun; 226(6):988-995. PubMed ID: 29428231
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the β-Catenin Coactivator BCL9-2 in Breast Cancer Cells.
    El-Hage P; Petitalot A; Monsoro-Burq AH; Maczkowiak F; Driouch K; Formstecher E; Camonis J; Sabbah M; Bièche I; Lidereau R; Lallemand F
    Mol Cancer Res; 2015 May; 13(5):902-12. PubMed ID: 25678599
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Efficient microwave assisted synthesis of novel 1,2,3-triazole-sucrose derivatives by cycloaddition reaction of sucrose azides and terminal alkynes.
    Potewar TM; Petrova KT; Barros MT
    Carbohydr Res; 2013 Sep; 379():60-7. PubMed ID: 23872329
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of 1-Benzoyl 4-Phenoxypiperidines as Small-Molecule Inhibitors of the β-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction.
    Li Z; Zhang M; Teuscher KB; Ji H
    J Med Chem; 2021 Aug; 64(15):11195-11218. PubMed ID: 34270257
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of quercetin derivatives as novel β-catenin/B-cell lymphoma 9 protein-protein interaction inhibitors.
    Shen LA; Peng X; Bao Y; Liu C; Zhang H; Li J; Zhu D; Zhang Q
    Eur J Med Chem; 2023 Feb; 247():115075. PubMed ID: 36599228
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Facile entry into triazole fused heterocycles via sulfamidate derived azido-alkynes.
    Sai Sudhir V; Phani Kumar NY; Nasir Baig RB; Chandrasekaran S
    J Org Chem; 2009 Oct; 74(19):7588-91. PubMed ID: 19725506
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid.
    de la Roche M; Rutherford TJ; Gupta D; Veprintsev DB; Saxty B; Freund SM; Bienz M
    Nat Commun; 2012 Feb; 3():680. PubMed ID: 22353711
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New ZW4864 Derivatives as Small-Molecule Inhibitors for the β-Catenin/BCL9 Protein-Protein Interaction.
    Wang Z; Zhang M; Thompson HM; Ji H
    ACS Med Chem Lett; 2022 May; 13(5):865-870. PubMed ID: 35586435
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.