192 related articles for article (PubMed ID: 22201128)
1. RAG-induced DNA double-strand breaks signal through Pim2 to promote pre-B cell survival and limit proliferation.
Bednarski JJ; Nickless A; Bhattacharya D; Amin RH; Schlissel MS; Sleckman BP
J Exp Med; 2012 Jan; 209(1):11-7. PubMed ID: 22201128
[TBL] [Abstract][Full Text] [Related]
2. RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals.
Bednarski JJ; Pandey R; Schulte E; White LS; Chen BR; Sandoval GJ; Kohyama M; Haldar M; Nickless A; Trott A; Cheng G; Murphy KM; Bassing CH; Payton JE; Sleckman BP
J Exp Med; 2016 Feb; 213(2):209-23. PubMed ID: 26834154
[TBL] [Abstract][Full Text] [Related]
3. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks.
Helmink BA; Bredemeyer AL; Lee BS; Huang CY; Sharma GG; Walker LM; Bednarski JJ; Lee WL; Pandita TK; Bassing CH; Sleckman BP
J Exp Med; 2009 Mar; 206(3):669-79. PubMed ID: 19221393
[TBL] [Abstract][Full Text] [Related]
4. Nuclease-independent functions of RAG1 direct distinct DNA damage responses in B cells.
Johnston R; Mathias B; Crowley SJ; Schmidt HA; White LS; Mosammaparast N; Green AM; Bednarski JJ
EMBO Rep; 2023 Jan; 24(1):e55429. PubMed ID: 36382770
[TBL] [Abstract][Full Text] [Related]
5. The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements.
Steinel NC; Lee BS; Tubbs AT; Bednarski JJ; Schulte E; Yang-Iott KS; Schatz DG; Sleckman BP; Bassing CH
J Exp Med; 2013 Feb; 210(2):233-9. PubMed ID: 23382544
[TBL] [Abstract][Full Text] [Related]
6. Proviral integration site 2 is required for interleukin-6 expression induced by interleukin-1, tumour necrosis factor-α and lipopolysaccharide.
Yang J; Li X; Hanidu A; Htut TM; Sellati R; Wang L; Jiang H; Li J
Immunology; 2010 Oct; 131(2):174-82. PubMed ID: 20465571
[TBL] [Abstract][Full Text] [Related]
7. PIM kinases are essential for chronic lymphocytic leukemia cell survival (PIM2/3) and CXCR4-mediated microenvironmental interactions (PIM1).
Decker S; Finter J; Forde AJ; Kissel S; Schwaller J; Mack TS; Kuhn A; Gray N; Follo M; Jumaa H; Burger M; Zirlik K; Pfeifer D; Miduturu CV; Eibel H; Veelken H; Dierks C
Mol Cancer Ther; 2014 May; 13(5):1231-45. PubMed ID: 24659821
[TBL] [Abstract][Full Text] [Related]
8. MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks.
Fraser M; Harding SM; Zhao H; Coackley C; Durocher D; Bristow RG
Cell Cycle; 2011 Jul; 10(13):2218-32. PubMed ID: 21623170
[TBL] [Abstract][Full Text] [Related]
9. RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex.
Soodgupta D; White LS; Yang W; Johnston R; Andrews JM; Kohyama M; Murphy KM; Mosammaparast N; Payton JE; Bednarski JJ
Cell Rep; 2019 Oct; 29(4):829-843.e5. PubMed ID: 31644907
[TBL] [Abstract][Full Text] [Related]
10. Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis.
Mahowald GK; Baron JM; Mahowald MA; Kulkarni S; Bredemeyer AL; Bassing CH; Sleckman BP
Proc Natl Acad Sci U S A; 2009 Oct; 106(43):18339-44. PubMed ID: 19820166
[TBL] [Abstract][Full Text] [Related]
11. Integrated signaling in developing lymphocytes: the role of DNA damage responses.
Bednarski JJ; Sleckman BP
Cell Cycle; 2012 Nov; 11(22):4129-34. PubMed ID: 23032308
[TBL] [Abstract][Full Text] [Related]
12. Loss of PIM2 enhances the anti-proliferative effect of the pan-PIM kinase inhibitor AZD1208 in non-Hodgkin lymphomas.
Kreuz S; Holmes KB; Tooze RM; Lefevre PF
Mol Cancer; 2015 Dec; 14():205. PubMed ID: 26643319
[TBL] [Abstract][Full Text] [Related]
13. Regulation of cell survival during B lymphopoiesis: apoptosis and Bcl-2/Bax content of precursor B cells in bone marrow of mice with altered expression of IL-7 and recombinase-activating gene-2.
Lu L; Chaudhury P; Osmond DG
J Immunol; 1999 Feb; 162(4):1931-40. PubMed ID: 9973461
[TBL] [Abstract][Full Text] [Related]
14. Repair of chromosomal RAG-mediated DNA breaks by mutant RAG proteins lacking phosphatidylinositol 3-like kinase consensus phosphorylation sites.
Gapud EJ; Lee BS; Mahowald GK; Bassing CH; Sleckman BP
J Immunol; 2011 Aug; 187(4):1826-34. PubMed ID: 21742970
[TBL] [Abstract][Full Text] [Related]
15. Ganglioside loss promotes survival primarily by activating integrin-linked kinase/Akt without phosphoinositide 3-OH kinase signaling.
Sun P; Wang XQ; Lopatka K; Bangash S; Paller AS
J Invest Dermatol; 2002 Jul; 119(1):107-17. PubMed ID: 12164932
[TBL] [Abstract][Full Text] [Related]
16. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes.
Helmink BA; Tubbs AT; Dorsett Y; Bednarski JJ; Walker LM; Feng Z; Sharma GG; McKinnon PJ; Zhang J; Bassing CH; Sleckman BP
Nature; 2011 Jan; 469(7329):245-9. PubMed ID: 21160476
[TBL] [Abstract][Full Text] [Related]
17. NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity.
Ochodnicka-Mackovicova K; Bahjat M; Bloedjes TA; Maas C; de Bruin AM; Bende RJ; van Noesel CJ; Guikema JE
Blood; 2015 Sep; 126(11):1324-35. PubMed ID: 26153519
[TBL] [Abstract][Full Text] [Related]
18. PIM2 inhibition as a rational therapeutic approach in B-cell lymphoma.
Gómez-Abad C; Pisonero H; Blanco-Aparicio C; Roncador G; González-Menchén A; Martinez-Climent JA; Mata E; Rodríguez ME; Muñoz-González G; Sánchez-Beato M; Leal JF; Bischoff JR; Piris MA
Blood; 2011 Nov; 118(20):5517-27. PubMed ID: 21937691
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression.
Kronschnabl P; Grünweller A; Hartmann RK; Aigner A; Weirauch U
Int J Oncol; 2020 Feb; 56(2):448-459. PubMed ID: 31894300
[TBL] [Abstract][Full Text] [Related]
20. PIM2 kinase is induced by cisplatin in ovarian cancer cells and limits drug efficacy.
Musiani D; Hammond DE; Cirillo L; Erriquez J; Olivero M; Clague MJ; Di Renzo MF
J Proteome Res; 2014 Nov; 13(11):4970-82. PubMed ID: 25099161
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
