95 related articles for article (PubMed ID: 22205087)
1. p53, a pivotal effector of a functional cross-talk linking presenilins and Pen-2.
Checler F; Dunys J
Neurodegener Dis; 2012; 10(1-4):52-5. PubMed ID: 22205087
[TBL] [Abstract][Full Text] [Related]
2. p53 is regulated by and regulates members of the gamma-secretase complex.
Checler F; Dunys J; Pardossi-Piquard R; Alves da Costa C
Neurodegener Dis; 2010; 7(1-3):50-5. PubMed ID: 20160459
[TBL] [Abstract][Full Text] [Related]
3. p53-Dependent Aph-1 and Pen-2 anti-apoptotic phenotype requires the integrity of the gamma-secretase complex but is independent of its activity.
Dunys J; Kawarai T; Sevalle J; Dolcini V; George-Hyslop PS; Da Costa CA; Checler F
J Biol Chem; 2007 Apr; 282(14):10516-25. PubMed ID: 17276981
[TBL] [Abstract][Full Text] [Related]
4. Immature nicastrin stabilizes APH-1 independent of PEN-2 and presenilin: identification of nicastrin mutants that selectively interact with APH-1.
Shirotani K; Edbauer D; Kostka M; Steiner H; Haass C
J Neurochem; 2004 Jun; 89(6):1520-7. PubMed ID: 15189355
[TBL] [Abstract][Full Text] [Related]
5. Pharmacological evidences for DFK167-sensitive presenilin-independent gamma-secretase-like activity.
Sevalle J; Ayral E; Hernandez JF; Martinez J; Checler F
J Neurochem; 2009 Jul; 110(1):275-83. PubMed ID: 19457123
[TBL] [Abstract][Full Text] [Related]
6. p53-dependent control of transactivation of the Pen2 promoter by presenilins.
Dunys J; Sevalle J; Giaime E; Pardossi-Piquard R; Vitek MP; Renbaum P; Levy-Lahad E; Zhang YW; Xu H; Checler F; da Costa CA
J Cell Sci; 2009 Nov; 122(Pt 21):4003-8. PubMed ID: 19889971
[TBL] [Abstract][Full Text] [Related]
7. A family of membrane proteins associated with presenilin expression and gamma-secretase function.
Araki W; Takahashi-Sasaki N; Chui DH; Saito S; Takeda K; Shirotani K; Takahashi K; Murayama KS; Kametani F; Shiraishi H; Komano H; Tabira T
FASEB J; 2008 Mar; 22(3):819-27. PubMed ID: 17928364
[TBL] [Abstract][Full Text] [Related]
8. Presenilin modulates Pen-2 levels posttranslationally by protecting it from proteasomal degradation.
Crystal AS; Morais VA; Fortna RR; Carlin D; Pierson TC; Wilson CA; Lee VM; Doms RW
Biochemistry; 2004 Mar; 43(12):3555-63. PubMed ID: 15035625
[TBL] [Abstract][Full Text] [Related]
9. Presenilins: how much more than γ-secretase?!
Coen K; Annaert W
Biochem Soc Trans; 2010 Dec; 38(6):1474-8. PubMed ID: 21118110
[TBL] [Abstract][Full Text] [Related]
10. Length and overall sequence of the PEN-2 C-terminal domain determines its function in the stabilization of presenilin fragments.
Prokop S; Haass C; Steiner H
J Neurochem; 2005 Jul; 94(1):57-62. PubMed ID: 15953349
[TBL] [Abstract][Full Text] [Related]
11. gamma-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal gamma-secretase activity.
Strömberg K; Hansson EM; Laudon H; Bergstedt S; Näslund J; Lundkvist J; Lendahl U
J Neurochem; 2005 Nov; 95(3):880-90. PubMed ID: 16135086
[TBL] [Abstract][Full Text] [Related]
12. Structure-activity relationship of presenilin in γ-secretase-mediated intramembrane cleavage.
Cai T; Tomita T
Semin Cell Dev Biol; 2020 Sep; 105():102-109. PubMed ID: 32171519
[TBL] [Abstract][Full Text] [Related]
13. p53-dependent control of cell death by nicastrin: lack of requirement for presenilin-dependent gamma-secretase complex.
Pardossi-Piquard R; Dunys J; Giaime E; Guillot-Sestier MV; St George-Hyslop P; Checler F; Alves da Costa C
J Neurochem; 2009 Apr; 109(1):225-37. PubMed ID: 19187441
[TBL] [Abstract][Full Text] [Related]
14. PEN-2 enhances gamma-cleavage after presenilin heterodimer formation.
Shiraishi H; Sai X; Wang HQ; Maeda Y; Kurono Y; Nishimura M; Yanagisawa K; Komano H
J Neurochem; 2004 Sep; 90(6):1402-13. PubMed ID: 15341524
[TBL] [Abstract][Full Text] [Related]
15. In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc.
Hoke DE; Tan JL; Ilaya NT; Culvenor JG; Smith SJ; White AR; Masters CL; Evin GM
FEBS J; 2005 Nov; 272(21):5544-57. PubMed ID: 16262694
[TBL] [Abstract][Full Text] [Related]
16. Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membrane.
Kaether C; Lammich S; Edbauer D; Ertl M; Rietdorf J; Capell A; Steiner H; Haass C
J Cell Biol; 2002 Aug; 158(3):551-61. PubMed ID: 12147673
[TBL] [Abstract][Full Text] [Related]
17. Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo.
Brijbassi S; Amtul Z; Newbigging S; Westaway D; St George-Hyslop P; Rozmahel RF
Neurobiol Dis; 2007 Feb; 25(2):291-6. PubMed ID: 17071095
[TBL] [Abstract][Full Text] [Related]
18. Novel research horizons for presenilins and γ-secretases in cell biology and disease.
De Strooper B; Annaert W
Annu Rev Cell Dev Biol; 2010; 26():235-60. PubMed ID: 20604710
[TBL] [Abstract][Full Text] [Related]
19. Critical role of presenilin-dependent γ-secretase activity in DNA damage-induced promyelocytic leukemia protein expression and apoptosis.
Song H; Boo JH; Kim KH; Kim C; Kim YE; Ahn JH; Jeon GS; Ryu H; Kang DE; Mook-Jung I
Cell Death Differ; 2013 Apr; 20(4):639-48. PubMed ID: 23306558
[TBL] [Abstract][Full Text] [Related]
20. Increase in p53 protein levels by presenilin 1 gene mutations and its inhibition by secretase inhibitors.
Ma L; Ohyagi Y; Miyoshi K; Sakae N; Motomura K; Taniwaki T; Furuya H; Takeda K; Tabira T; Kira J
J Alzheimers Dis; 2009; 16(3):565-75. PubMed ID: 19276551
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
