95 related articles for article (PubMed ID: 22205087)
21. γ-Secretase component presenilin is important for microglia β-amyloid clearance.
Farfara D; Trudler D; Segev-Amzaleg N; Galron R; Stein R; Frenkel D
Ann Neurol; 2011 Jan; 69(1):170-80. PubMed ID: 21280087
[TBL] [Abstract][Full Text] [Related]
22. Beta-amyloid secretases and beta-amloid degrading enzyme expression in lens.
Li G; Percontino L; Sun Q; Qazi AS; Frederikse PH
Mol Vis; 2003 May; 9():179-83. PubMed ID: 12740567
[TBL] [Abstract][Full Text] [Related]
23. Detergent-dependent dissociation of active gamma-secretase reveals an interaction between Pen-2 and PS1-NTF and offers a model for subunit organization within the complex.
Fraering PC; LaVoie MJ; Ye W; Ostaszewski BL; Kimberly WT; Selkoe DJ; Wolfe MS
Biochemistry; 2004 Jan; 43(2):323-33. PubMed ID: 14717586
[TBL] [Abstract][Full Text] [Related]
24. Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex.
Evin G; Canterford LD; Hoke DE; Sharples RA; Culvenor JG; Masters CL
Biochemistry; 2005 Mar; 44(11):4332-41. PubMed ID: 15766262
[TBL] [Abstract][Full Text] [Related]
25. The gamma/epsilon-secretase-derived APP intracellular domain fragments regulate p53.
Checler F; Sunyach C; Pardossi-Piquard R; Sévalle J; Vincent B; Kawarai T; Girardot N; St George-Hyslop P; da Costa CA
Curr Alzheimer Res; 2007 Sep; 4(4):423-6. PubMed ID: 17908046
[TBL] [Abstract][Full Text] [Related]
26. Assembly, trafficking and function of gamma-secretase.
Kaether C; Haass C; Steiner H
Neurodegener Dis; 2006; 3(4-5):275-83. PubMed ID: 17047368
[TBL] [Abstract][Full Text] [Related]
27. Abeta42 overproduction associated with structural changes in the catalytic pore of gamma-secretase: common effects of Pen-2 N-terminal elongation and fenofibrate.
Isoo N; Sato C; Miyashita H; Shinohara M; Takasugi N; Morohashi Y; Tsuji S; Tomita T; Iwatsubo T
J Biol Chem; 2007 Apr; 282(17):12388-96. PubMed ID: 17329245
[TBL] [Abstract][Full Text] [Related]
28. Minor contribution of presenilin 2 for γ-secretase activity in mouse embryonic fibroblasts and adult mouse brain.
Frånberg J; Svensson AI; Winblad B; Karlström H; Frykman S
Biochem Biophys Res Commun; 2011 Jan; 404(1):564-8. PubMed ID: 21146496
[TBL] [Abstract][Full Text] [Related]
29. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
Shirotani K; Tomioka M; Kremmer E; Haass C; Steiner H
Neurobiol Dis; 2007 Jul; 27(1):102-7. PubMed ID: 17560791
[TBL] [Abstract][Full Text] [Related]
30. Reconstitution of gamma-secretase activity.
Edbauer D; Winkler E; Regula JT; Pesold B; Steiner H; Haass C
Nat Cell Biol; 2003 May; 5(5):486-8. PubMed ID: 12679784
[TBL] [Abstract][Full Text] [Related]
31. p53-Dependent transcriptional control of cellular prion by presenilins.
Vincent B; Sunyach C; Orzechowski HD; St George-Hyslop P; Checler F
J Neurosci; 2009 May; 29(20):6752-60. PubMed ID: 19458243
[TBL] [Abstract][Full Text] [Related]
32. TMP21 regulates Abeta production but does not affect caspase-3, p53, and neprilysin.
Dolcini V; Dunys J; Sevalle J; Chen F; Guillot-Sestier MV; St George-Hyslop P; Fraser PE; Checler F
Biochem Biophys Res Commun; 2008 Jun; 371(1):69-74. PubMed ID: 18405662
[TBL] [Abstract][Full Text] [Related]
33. The Alzheimer's disease-associated gamma-secretase complex: functional domains in the presenilin 1 protein.
Laudon H; Winblad B; Näslund J
Physiol Behav; 2007 Sep; 92(1-2):115-20. PubMed ID: 17588625
[TBL] [Abstract][Full Text] [Related]
34. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides.
Phiel CJ; Wilson CA; Lee VM; Klein PS
Nature; 2003 May; 423(6938):435-9. PubMed ID: 12761548
[TBL] [Abstract][Full Text] [Related]
35. Presenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formation.
Edbauer D; Winkler E; Haass C; Steiner H
Proc Natl Acad Sci U S A; 2002 Jun; 99(13):8666-71. PubMed ID: 12048259
[TBL] [Abstract][Full Text] [Related]
36. Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice.
Tournoy J; Bossuyt X; Snellinx A; Regent M; Garmyn M; Serneels L; Saftig P; Craessaerts K; De Strooper B; Hartmann D
Hum Mol Genet; 2004 Jul; 13(13):1321-31. PubMed ID: 15128703
[TBL] [Abstract][Full Text] [Related]
37. CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production.
Zhou S; Zhou H; Walian PJ; Jap BK
Proc Natl Acad Sci U S A; 2005 May; 102(21):7499-504. PubMed ID: 15890777
[TBL] [Abstract][Full Text] [Related]
38. Contribution of the Presenilins in the cell biology, structure and function of γ-secretase.
Escamilla-Ayala A; Wouters R; Sannerud R; Annaert W
Semin Cell Dev Biol; 2020 Sep; 105():12-26. PubMed ID: 32146031
[TBL] [Abstract][Full Text] [Related]
39. Presenilins and γ-Secretase in Membrane Proteostasis.
Oikawa N; Walter J
Cells; 2019 Mar; 8(3):. PubMed ID: 30823664
[TBL] [Abstract][Full Text] [Related]
40. β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models.
Goiran T; Duplan E; Chami M; Bourgeois A; El Manaa W; Rouland L; Dunys J; Lauritzen I; You H; Stambolic V; Biféri MG; Barkats M; Pimplikar SW; Sergeant N; Colin M; Morais VA; Pardossi-Piquard R; Checler F; Alves da Costa C
Biol Psychiatry; 2018 Mar; 83(5):416-427. PubMed ID: 28587718
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
