BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 22205779)

  • 1. Cyclosporine A- and tacrolimus-mediated inhibition of CYP3A4 and CYP3A5 in vitro.
    Amundsen R; Åsberg A; Ohm IK; Christensen H
    Drug Metab Dispos; 2012 Apr; 40(4):655-61. PubMed ID: 22205779
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyclosporine A, but not tacrolimus, shows relevant inhibition of organic anion-transporting protein 1B1-mediated transport of atorvastatin.
    Amundsen R; Christensen H; Zabihyan B; Asberg A
    Drug Metab Dispos; 2010 Sep; 38(9):1499-504. PubMed ID: 20519340
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Risk Assessment of Drug-Drug Interactions of Calcineurin Inhibitors Affecting Sirolimus Pharmacokinetics in Renal Transplant Patients.
    Emoto C; Vinks AA; Fukuda T
    Ther Drug Monit; 2016 Oct; 38(5):607-13. PubMed ID: 27310200
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impact of POR*28 on the pharmacokinetics of tacrolimus and cyclosporine A in renal transplant patients.
    Elens L; Hesselink DA; Bouamar R; Budde K; de Fijter JW; De Meyer M; Mourad M; Kuypers DR; Haufroid V; van Gelder T; van Schaik RH
    Ther Drug Monit; 2014 Feb; 36(1):71-9. PubMed ID: 24061445
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of a new functional CYP3A4 polymorphism on calcineurin inhibitors' dose requirements and trough blood levels in stable renal transplant patients.
    Elens L; van Schaik RH; Panin N; de Meyer M; Wallemacq P; Lison D; Mourad M; Haufroid V
    Pharmacogenomics; 2011 Oct; 12(10):1383-96. PubMed ID: 21902502
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reversible, time-dependent inhibition of CYP3A-mediated metabolism of midazolam and tacrolimus by telaprevir in human liver microsomes.
    Chapron B; Risler L; Phillips B; Collins C; Thummel K; Shen D
    J Pharm Pharm Sci; 2015; 18(1):101-11. PubMed ID: 25877445
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The influence of CYP3A5 expression on the extent of hepatic CYP3A inhibition is substrate-dependent: an in vitro-in vivo evaluation.
    Isoherranen N; Ludington SR; Givens RC; Lamba JK; Pusek SN; Dees EC; Blough DK; Iwanaga K; Hawke RL; Schuetz EG; Watkins PB; Thummel KE; Paine MF
    Drug Metab Dispos; 2008 Jan; 36(1):146-54. PubMed ID: 17954524
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part II.
    Staatz CE; Goodman LK; Tett SE
    Clin Pharmacokinet; 2010 Apr; 49(4):207-21. PubMed ID: 20214406
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Selective mechanism-based inactivation of CYP3A4 by CYP3cide (PF-04981517) and its utility as an in vitro tool for delineating the relative roles of CYP3A4 versus CYP3A5 in the metabolism of drugs.
    Walsky RL; Obach RS; Hyland R; Kang P; Zhou S; West M; Geoghegan KF; Helal CJ; Walker GS; Goosen TC; Zientek MA
    Drug Metab Dispos; 2012 Sep; 40(9):1686-97. PubMed ID: 22645092
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5.
    Patki KC; Von Moltke LL; Greenblatt DJ
    Drug Metab Dispos; 2003 Jul; 31(7):938-44. PubMed ID: 12814972
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Significant impact of gene polymorphisms on tacrolimus but not cyclosporine dosing in Asian renal transplant recipients.
    Loh PT; Lou HX; Zhao Y; Chin YM; Vathsala A
    Transplant Proc; 2008 Jun; 40(5):1690-5. PubMed ID: 18589174
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro-in vivo extrapolations to evaluate the effect of concomitant drugs on tacrolimus (FK506) exposure.
    Oda K; Yamano K; Otsuka Y
    Biopharm Drug Dispos; 2015 Jul; 36(5):265-74. PubMed ID: 25600613
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prediction of crizotinib-midazolam interaction using the Simcyp population-based simulator: comparison of CYP3A time-dependent inhibition between human liver microsomes versus hepatocytes.
    Mao J; Johnson TR; Shen Z; Yamazaki S
    Drug Metab Dispos; 2013 Feb; 41(2):343-52. PubMed ID: 23129213
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cyclosporine A and tacrolimus: in vitro investigations on the differential interactions with the cytochrome P450 system in rat and human liver.
    Lupp A; Kuhn UD; Herwig R; Karge E; Rost M; Scheele J; Fleck C
    Exp Toxicol Pathol; 2003 Jun; 54(5-6):467-73. PubMed ID: 12877359
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Relative contributions of cytochrome CYP3A4 versus CYP3A5 for CYP3A-cleared drugs assessed in vitro using a CYP3A4-selective inactivator (CYP3cide).
    Tseng E; Walsky RL; Luzietti RA; Harris JJ; Kosa RE; Goosen TC; Zientek MA; Obach RS
    Drug Metab Dispos; 2014 Jul; 42(7):1163-73. PubMed ID: 24737844
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of cytochrome P-450 3A (CYP3A) in human intestinal and liver microsomes: comparison of Ki values and impact of CYP3A5 expression.
    Gibbs MA; Thummel KE; Shen DD; Kunze KL
    Drug Metab Dispos; 1999 Feb; 27(2):180-7. PubMed ID: 9929500
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of cyclosporine and tacrolimus on cytochrome p450 activities in human liver microsomes.
    Niwa T; Yamamoto S; Saito M; Shiraga T; Takagi A
    Yakugaku Zasshi; 2007 Jan; 127(1):209-16. PubMed ID: 17202802
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro-in vivo extrapolation of zolpidem as a perpetrator of metabolic interactions involving CYP3A.
    Polasek TM; Sadagopal JS; Elliot DJ; Miners JO
    Eur J Clin Pharmacol; 2010 Mar; 66(3):275-83. PubMed ID: 20012430
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sorafenib and sunitinib, two anticancer drugs, inhibit CYP3A4-mediated and activate CY3A5-mediated midazolam 1'-hydroxylation.
    Sugiyama M; Fujita K; Murayama N; Akiyama Y; Yamazaki H; Sasaki Y
    Drug Metab Dispos; 2011 May; 39(5):757-62. PubMed ID: 21266595
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro investigations on the differential pro-oxidant and/or antioxidant properties of cyclosporin A and tacrolimus in human and rat liver microsomes.
    Lupp A; Kuhn UD; Karge E; Adam G; Fleck C
    Int J Clin Pharmacol Ther; 2006 May; 44(5):225-32. PubMed ID: 16724577
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.