BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

96 related articles for article (PubMed ID: 22207148)

  • 1. Dominant lethal mutations of topoisomerase II inhibitors etoposide and merbarone in male mice: a mechanistic study.
    Attia SM
    Arch Toxicol; 2012 May; 86(5):725-31. PubMed ID: 22207148
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Germ cell mutagenicity of topoisomerase I inhibitor topotecan detected in the male mouse-dominant lethal study.
    Attia SM; Ahmad SF; Abd-Ellah MF; Hamada FM; Bakheet SA
    Food Chem Toxicol; 2013 Dec; 62():470-4. PubMed ID: 24036143
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential cell cycle-specificity for chromosomal damage induced by merbarone and etoposide in V79 cells.
    Wang L; Roy SK; Eastmond DA
    Mutat Res; 2007 Mar; 616(1-2):70-82. PubMed ID: 17174356
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of the DNA topoisomerase II inhibitor merbarone in male mouse meiotic divisions in vivo: cell cycle arrest and induction of aneuploidy.
    Kallio M; Lähdetie J
    Environ Mol Mutagen; 1997; 29(1):16-27. PubMed ID: 9020303
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The DNA topoisomerase II catalytic inhibitor merbarone is genotoxic and induces endoreduplication.
    Pastor N; Domínguez I; Orta ML; Campanella C; Mateos S; Cortés F
    Mutat Res; 2012; 738-739():45-51. PubMed ID: 22921906
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chlornaphazine and chlorambucil induce dominant lethal mutations in male mice.
    Barnett LB; Lewis SE
    Mutat Res; 2003 Mar; 543(2):145-54. PubMed ID: 12644184
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Catalytic inhibitors of topoisomerase II are DNA-damaging agents: induction of chromosomal damage by merbarone and ICRF-187.
    Wang L; Eastmond DA
    Environ Mol Mutagen; 2002; 39(4):348-56. PubMed ID: 12112387
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dominant lethal effects of nocodazole in germ cells of male mice.
    Attia SM; Ahmad SF; Okash RM; Bakheet SA
    Food Chem Toxicol; 2015 Mar; 77():101-4. PubMed ID: 25595372
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of novel human leukemic cell lines selected for resistance to merbarone, a catalytic inhibitor of DNA topoisomerase II.
    Kusumoto H; Rodgers QE; Boege F; Raimondi SC; Beck WT
    Cancer Res; 1996 Jun; 56(11):2573-83. PubMed ID: 8653700
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Etoposide and merbarone are clastogenic and aneugenic in the mouse bone marrow micronucleus test complemented by fluorescence in situ hybridization with the mouse minor satellite DNA probe.
    Attia SM; Kliesch U; Schriever-Schwemmer G; Badary OA; Hamada FM; Adler ID
    Environ Mol Mutagen; 2003; 41(2):99-103. PubMed ID: 12605378
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unlike other chemicals, etoposide (a topoisomerase-II inhibitor) produces peak mutagenicity in primary spermatocytes of the mouse.
    Russell LB; Hunsicker PR; Johnson DK; Shelby MD
    Mutat Res; 1998 May; 400(1-2):279-86. PubMed ID: 9685680
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of dominant lethal mutations by Ascaris trypsin inhibitor in male mice.
    Blaszkowska J
    Reprod Toxicol; 2010 Jan; 29(1):113-9. PubMed ID: 19737609
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutagenicity of Ascaris chymotrypsin inhibitor in germ cells of mice.
    Blaszkowska J
    Cell Biol Toxicol; 2008 Jun; 24(3):213-24. PubMed ID: 17674131
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of micronuclei induced in mouse early spermatids by mitomycin C, vinblastine sulfate or etoposide using fluorescence in situ hybridization.
    Kallio M; Lähdetie J
    Mutagenesis; 1993 Nov; 8(6):561-7. PubMed ID: 8133786
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oncofetal HMGA2 attenuates genotoxic damage induced by topoisomerase II target compounds through the regulation of local DNA topology.
    Ahmed SM; Dröge P
    Mol Oncol; 2019 Oct; 13(10):2062-2078. PubMed ID: 31271486
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ICRF-187 rescue in etoposide treatment in vivo. A model targeting high-dose topoisomerase II poisons to CNS tumors.
    Holm B; Jensen PB; Sehested M
    Cancer Chemother Pharmacol; 1996; 38(3):203-9. PubMed ID: 8646793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. G2 arrest in response to topoisomerase II inhibitors: the role of p53.
    Clifford B; Beljin M; Stark GR; Taylor WR
    Cancer Res; 2003 Jul; 63(14):4074-81. PubMed ID: 12874009
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular cytogenetic analysis in mouse sperm of chemically induced aneuploidy: studies with topoisomerase II inhibitors.
    Attia SM; Schmid TE; Badary OA; Hamada FM; Adler ID
    Mutat Res; 2002 Sep; 520(1-2):1-13. PubMed ID: 12297139
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Merbarone, a catalytic inhibitor of DNA topoisomerase II, induces apoptosis in CEM cells through activation of ICE/CED-3-like protease.
    Khélifa T; Beck WT
    Mol Pharmacol; 1999 Mar; 55(3):548-56. PubMed ID: 10051540
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone.
    Drake FH; Hofmann GA; Mong SM; Bartus JO; Hertzberg RP; Johnson RK; Mattern MR; Mirabelli CK
    Cancer Res; 1989 May; 49(10):2578-83. PubMed ID: 2540903
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.