These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 22208362)

  • 1. Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass.
    Vivas Y; Martínez-García C; Izquierdo A; Garcia-Garcia F; Callejas S; Velasco I; Campbell M; Ros M; Dopazo A; Dopazo J; Vidal-Puig A; Medina-Gomez G
    BMC Med Genomics; 2011 Dec; 4():86. PubMed ID: 22208362
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of PPARγ specifically in pancreatic β-cells exacerbates obesity-induced glucose intolerance, reduces β-cell mass, and alters islet lipid metabolism in male mice.
    Hogh KL; Craig MN; Uy CE; Nygren H; Asadi A; Speck M; Fraser JD; Rudecki AP; Baker RK; Orešič M; Gray SL
    Endocrinology; 2014 Oct; 155(10):3843-52. PubMed ID: 25051434
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Adaptation and failure of pancreatic beta cells in murine models with different degrees of metabolic syndrome.
    Medina-Gomez G; Yetukuri L; Velagapudi V; Campbell M; Blount M; Jimenez-Linan M; Ros M; Oresic M; Vidal-Puig A
    Dis Model Mech; 2009; 2(11-12):582-92. PubMed ID: 19841237
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.
    Davis DB; Lavine JA; Suhonen JI; Krautkramer KA; Rabaglia ME; Sperger JM; Fernandez LA; Yandell BS; Keller MP; Wang IM; Schadt EE; Attie AD
    Mol Endocrinol; 2010 Sep; 24(9):1822-34. PubMed ID: 20660304
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival.
    Lavine JA; Raess PW; Stapleton DS; Rabaglia ME; Suhonen JI; Schueler KL; Koltes JE; Dawson JA; Yandell BS; Samuelson LC; Beinfeld MC; Davis DB; Hellerstein MK; Keller MP; Attie AD
    Endocrinology; 2010 Aug; 151(8):3577-88. PubMed ID: 20534724
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of fibroblast growth factor 21 action induces insulin resistance, pancreatic islet hyperplasia and dysfunction in mice.
    So WY; Cheng Q; Xu A; Lam KS; Leung PS
    Cell Death Dis; 2015 Mar; 6(3):e1707. PubMed ID: 25811804
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Failure of the adaptive unfolded protein response in islets of obese mice is linked with abnormalities in β-cell gene expression and progression to diabetes.
    Chan JY; Luzuriaga J; Bensellam M; Biden TJ; Laybutt DR
    Diabetes; 2013 May; 62(5):1557-68. PubMed ID: 23274897
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced glucose-induced intracellular signaling promotes insulin hypersecretion: pancreatic beta-cell functional adaptations in a model of genetic obesity and prediabetes.
    Irles E; Ñeco P; Lluesma M; Villar-Pazos S; Santos-Silva JC; Vettorazzi JF; Alonso-Magdalena P; Carneiro EM; Boschero AC; Nadal Á; Quesada I
    Mol Cell Endocrinol; 2015 Mar; 404():46-55. PubMed ID: 25633666
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Accelerated renal disease is associated with the development of metabolic syndrome in a glucolipotoxic mouse model.
    Martínez-García C; Izquierdo A; Velagapudi V; Vivas Y; Velasco I; Campbell M; Burling K; Cava F; Ros M; Oresic M; Vidal-Puig A; Medina-Gomez G
    Dis Model Mech; 2012 Sep; 5(5):636-48. PubMed ID: 22773754
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of human insulin gene transcription by peroxisome proliferator-activated receptor gamma and thiazolidinedione oral antidiabetic drugs.
    Schinner S; Krätzner R; Baun D; Dickel C; Blume R; Oetjen E
    Br J Pharmacol; 2009 Jul; 157(5):736-45. PubMed ID: 19338578
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Peroxisome proliferator-activated receptor γ (PPARγ) and its target genes are downstream effectors of FoxO1 protein in islet β-cells: mechanism of β-cell compensation and failure.
    Gupta D; Leahy AA; Monga N; Peshavaria M; Jetton TL; Leahy JL
    J Biol Chem; 2013 Aug; 288(35):25440-25449. PubMed ID: 23788637
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Argonaute2 mediates compensatory expansion of the pancreatic β cell.
    Tattikota SG; Rathjen T; McAnulty SJ; Wessels HH; Akerman I; van de Bunt M; Hausser J; Esguerra JL; Musahl A; Pandey AK; You X; Chen W; Herrera PL; Johnson PR; O'Carroll D; Eliasson L; Zavolan M; Gloyn AL; Ferrer J; Shalom-Feuerstein R; Aberdam D; Poy MN
    Cell Metab; 2014 Jan; 19(1):122-34. PubMed ID: 24361012
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.
    Medina-Gomez G; Gray SL; Yetukuri L; Shimomura K; Virtue S; Campbell M; Curtis RK; Jimenez-Linan M; Blount M; Yeo GS; Lopez M; Seppänen-Laakso T; Ashcroft FM; Oresic M; Vidal-Puig A
    PLoS Genet; 2007 Apr; 3(4):e64. PubMed ID: 17465682
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased perinatal remodelling of the pancreas in somatostatin-deficient mice: potential role of transforming growth factor-beta signalling in regulating beta cell growth in early life.
    Richardson CC; To K; Foot VL; Hauge-Evans AC; Carmignac D; Christie MR
    Horm Metab Res; 2015 Jan; 47(1):56-63. PubMed ID: 25350519
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transcriptome analysis of islets from diabetes-resistant and diabetes-prone obese mice reveals novel gene regulatory networks involved in beta-cell compensation and failure.
    Chan JY; Bensellam M; Lin RCY; Liang C; Lee K; Jonas JC; Laybutt DR
    FASEB J; 2021 Jun; 35(6):e21608. PubMed ID: 33977593
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fibroblast growth factor 21 protects against lipotoxicity-induced pancreatic β-cell dysfunction via regulation of AMPK signaling and lipid metabolism.
    Xie T; So WY; Li XY; Leung PS
    Clin Sci (Lond); 2019 Oct; 133(19):2029-2044. PubMed ID: 31654570
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Physiologic and pharmacologic modulation of glucose-dependent insulinotropic polypeptide (GIP) receptor expression in beta-cells by peroxisome proliferator-activated receptor (PPAR)-gamma signaling: possible mechanism for the GIP resistance in type 2 diabetes.
    Gupta D; Peshavaria M; Monga N; Jetton TL; Leahy JL
    Diabetes; 2010 Jun; 59(6):1445-50. PubMed ID: 20332343
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insulinotropic effects of GPR120 agonists are altered in obese diabetic and obese non-diabetic states.
    Zhang D; So WY; Wang Y; Wu SY; Cheng Q; Leung PS
    Clin Sci (Lond); 2017 Feb; 131(3):247-260. PubMed ID: 27980130
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PPAR-γ activation increases insulin secretion through the up-regulation of the free fatty acid receptor GPR40 in pancreatic β-cells.
    Kim HS; Hwang YC; Koo SH; Park KS; Lee MS; Kim KW; Lee MK
    PLoS One; 2013; 8(1):e50128. PubMed ID: 23372643
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SetD7 (Set7/9) is a novel target of PPARγ that promotes the adaptive pancreatic β-cell glycemic response.
    Jetton TL; Flores-Bringas P; Leahy JL; Gupta D
    J Biol Chem; 2021 Nov; 297(5):101250. PubMed ID: 34592314
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.