BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 22210173)

  • 1. Synthesis and 5α-reductase inhibitory activity of C₂₁ steroids having 1,4-diene or 4,6-diene 20-ones and 4-azasteroid 20-oximes.
    Kim S; Kim YU; Ma E
    Molecules; 2011 Dec; 17(1):355-68. PubMed ID: 22210173
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of pregnane derivatives, their cytotoxicity on LNCap and PC-3 cells, and screening on 5alpha-reductase inhibitory activity.
    Kim S; Ma E
    Molecules; 2009 Nov; 14(11):4655-68. PubMed ID: 19924093
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor.
    Yao Z; Xu Y; Zhang M; Jiang S; Nicklaus MC; Liao C
    Bioorg Med Chem Lett; 2011 Jan; 21(1):475-8. PubMed ID: 21094046
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A review on steroidal 5α-reductase inhibitors for treatment of benign prostatic hyperplasia.
    Sun J; Xiang H; Yang LL; Chen JB
    Curr Med Chem; 2011; 18(23):3576-89. PubMed ID: 21756226
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and activity of novel 16-dehydropregnenolone acetate derivatives as inhibitors of type 1 5α-reductase and on cancer cell line SK-LU-1.
    Silva-Ortiz AV; Bratoeff E; Ramírez-Apan T; Heuze Y; Sánchez A; Soriano J; Cabeza M
    Bioorg Med Chem; 2015 Dec; 23(24):7535-42. PubMed ID: 26631442
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Steroidal pyrazolines and pyrazoles as potential 5α-reductase inhibitors: synthesis and biological evaluation.
    Banday AH; Shameem SA; Jeelani S
    Steroids; 2014 Dec; 92():13-9. PubMed ID: 25278254
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists.
    Lao K; Sun J; Wang C; Wang Y; You Q; Xiao H; Xiang H
    Bioorg Med Chem Lett; 2017 Sep; 27(17):4212-4217. PubMed ID: 28757062
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel C-6 substituted and unsubstituted pregnane derivatives as 5alpha-reductase inhibitors and their effect on hamster flank organs diameter size.
    Cabeza M; Zambrano A; Heuze I; Carrizales E; Palacios A; Segura T; Valencia N; Bratoeff E
    Steroids; 2009 Oct; 74(10-11):793-802. PubMed ID: 19406144
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and bioactivity of new Finasteride conjugate.
    Shuang Z; Jiazhen W; Lijuan Y; Zhuo L; Dahai Y; Jinfeng L; Jing Y; Yongtao L; En-Si W; Xuexun F
    Bioorg Med Chem Lett; 2011 Jun; 21(11):3439-42. PubMed ID: 21515045
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and evaluation of novel steroidal oxime inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase) and 5 alpha-reductase types 1 and 2.
    Hartmann RW; Hector M; Haidar S; Ehmer PB; Reichert W; Jose J
    J Med Chem; 2000 Nov; 43(22):4266-77. PubMed ID: 11063622
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: a legitimate approach.
    Aggarwal S; Thareja S; Bhardwaj TR; Haupenthal J; Hartmann RW; Kumar M
    Eur J Med Chem; 2012 Aug; 54():728-39. PubMed ID: 22776417
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5alpha-reductase inhibitors.
    Bratoeff E; Cabeza M; Pérez-Ornelas V; Recillas S; Heuze I
    J Steroid Biochem Mol Biol; 2008 Sep; 111(3-5):275-81. PubMed ID: 18644453
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors.
    Aggarwal S; Mahapatra MK; Kumar R; Bhardwaj TR; Hartmann RW; Haupenthal J; Kumar M
    Bioorg Med Chem; 2016 Feb; 24(4):779-88. PubMed ID: 26780831
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human osteoblast-like cells express predominantly steroid 5alpha-reductase type 1.
    Issa S; Schnabel D; Feix M; Wolf L; Schaefer HE; Russell DW; Schweikert HU
    J Clin Endocrinol Metab; 2002 Dec; 87(12):5401-7. PubMed ID: 12466325
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Steroid 5alpha-reductase inhibitors.
    Flores E; Bratoeff E; Cabeza M; Ramirez E; Quiroz A; Heuze I
    Mini Rev Med Chem; 2003 May; 3(3):225-37. PubMed ID: 12570838
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and screening of aromatase inhibitory activity of substituted C19 steroidal 17-oxime analogs.
    Pokhrel M; Ma E
    Molecules; 2011 Nov; 16(12):9868-85. PubMed ID: 22124202
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Substrate interaction with 5alpha-reductase enzyme: influence of the 17beta-chain chirality in the mechanism of action of 4-azasteroid inhibitors.
    Grisenti P; Magni A; Olgiati V; Manzocchi A; Ferraboschi P; Villani V; Pucciariello R; Celotti F
    Steroids; 2001 Nov; 66(11):803-10. PubMed ID: 11576619
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors.
    Arellano Y; Bratoeff E; Garrido M; Soriano J; Heuze Y; Cabeza M
    Steroids; 2011 Nov; 76(12):1241-6. PubMed ID: 21729714
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors.
    Karnsomwan W; Netcharoensirisuk P; Rungrotmongkol T; De-Eknamkul W; Chamni S
    Chem Pharm Bull (Tokyo); 2017; 65(3):253-260. PubMed ID: 28250347
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2.
    Lao K; Sun J; Wang C; Lyu W; Zhou B; Zhao R; Xu Q; You Q; Xiang H
    Steroids; 2017 Aug; 124():29-34. PubMed ID: 28549802
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.