BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

230 related articles for article (PubMed ID: 22210323)

  • 21. Rationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 Diabetes.
    Hecht R; Li YS; Sun J; Belouski E; Hall M; Hager T; Yie J; Wang W; Winters D; Smith S; Spahr C; Tam LT; Shen Z; Stanislaus S; Chinookoswong N; Lau Y; Sickmier A; Michaels ML; Boone T; Véniant MM; Xu J
    PLoS One; 2012; 7(11):e49345. PubMed ID: 23209571
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Insulin sensitizes FGF21 in glucose and lipid metabolisms via activating common AKT pathway.
    Yu D; Ye X; Wu Q; Li S; Yang Y; He J; Liu Y; Zhang X; Yuan Q; Liu M; Li D; Ren G
    Endocrine; 2016 Jun; 52(3):527-40. PubMed ID: 26607153
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Fibroblast growth factor-21 (FGF21) administration to early-lactating dairy cows. II. Pharmacokinetics, whole-animal performance, and lipid metabolism.
    Caixeta LS; Giesy SL; Krumm CS; Perfield JW; Butterfield A; Boisclair YR
    J Dairy Sci; 2019 Dec; 102(12):11597-11608. PubMed ID: 31548064
    [TBL] [Abstract][Full Text] [Related]  

  • 24. AKR-001, an Fc-FGF21 Analog, Showed Sustained Pharmacodynamic Effects on Insulin Sensitivity and Lipid Metabolism in Type 2 Diabetes Patients.
    Kaufman A; Abuqayyas L; Denney WS; Tillman EJ; Rolph T
    Cell Rep Med; 2020 Jul; 1(4):100057. PubMed ID: 33205064
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synthesis, characterization, and pharmacokinetic studies of PEGylated glucagon-like peptide-1.
    Lee SH; Lee S; Youn YS; Na DH; Chae SY; Byun Y; Lee KC
    Bioconjug Chem; 2005; 16(2):377-82. PubMed ID: 15769092
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Fibroblast growth factor 21 (FGF21) and glucagon-like peptide 1 contribute to diabetes resistance in glucagon receptor-deficient mice.
    Omar BA; Andersen B; Hald J; Raun K; Nishimura E; Ahrén B
    Diabetes; 2014 Jan; 63(1):101-10. PubMed ID: 24062250
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Liver-derived fibroblast growth factor 21 mediates effects of glucagon-like peptide-1 in attenuating hepatic glucose output.
    Liu J; Yang K; Yang J; Xiao W; Le Y; Yu F; Gu L; Lang S; Tian Q; Jin T; Wei R; Hong T
    EBioMedicine; 2019 Mar; 41():73-84. PubMed ID: 30827929
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Fibroblast growth factor 21 protects against lipotoxicity-induced pancreatic β-cell dysfunction via regulation of AMPK signaling and lipid metabolism.
    Xie T; So WY; Li XY; Leung PS
    Clin Sci (Lond); 2019 Oct; 133(19):2029-2044. PubMed ID: 31654570
    [TBL] [Abstract][Full Text] [Related]  

  • 29. PEGylated glucagon-like peptide-1 displays preserved effects on insulin release in isolated pancreatic islets and improved biological activity in db/db mice.
    Lee S; Youn YS; Lee SH; Byun Y; Lee KC
    Diabetologia; 2006 Jul; 49(7):1608-11. PubMed ID: 16586064
    [TBL] [Abstract][Full Text] [Related]  

  • 30. [Therapeutic effect of fibroblast growth factor 21 on hypertension induced by insulin resistance].
    Zhu SL; Ren GP; Zhang ZY; Wang WF; Ye XL; Han MM; Zhao JZ; Xu TY; Liu MY; Li DS
    Yao Xue Xue Bao; 2013 Sep; 48(9):1409-14. PubMed ID: 24358774
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Genetic fusion of human FGF21 to a synthetic polypeptide improves pharmacokinetics and pharmacodynamics in a mouse model of obesity.
    Yin J; Bao L; Tian H; Wang Q; Gao X; Yao W
    Br J Pharmacol; 2016 Jul; 173(14):2208-23. PubMed ID: 27339749
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Paracrine-endocrine FGF chimeras as potent therapeutics for metabolic diseases.
    Zhao L; Niu J; Lin H; Zhao J; Liu Y; Song Z; Xiang C; Wang X; Yang Y; Li X; Mohammadi M; Huang Z
    EBioMedicine; 2019 Oct; 48():462-477. PubMed ID: 31631034
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Fibroblast growth factor-21 (FGF21) administration to early-lactating dairy cows. I. Effects on signaling and indices of insulin action.
    Krumm CS; Giesy SL; Caixeta LS; Perfield JW; Sauerwein H; Moore BL; Boisclair YR
    J Dairy Sci; 2019 Dec; 102(12):11586-11596. PubMed ID: 31548053
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Low molecular weight (1 kDa) polyethylene glycol conjugation markedly enhances the hypoglycemic effects of intranasally administered exendin-4 in type 2 diabetic db/db mice.
    Kim TH; Park CW; Kim HY; Chi MH; Lee SK; Song YM; Jiang HH; Lim SM; Youn YS; Lee KC
    Biol Pharm Bull; 2012; 35(7):1076-83. PubMed ID: 22791155
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Pharmacokinetics (PK), pharmacodynamics (PD) and integrated PK/PD modeling of a novel long acting FGF21 clinical candidate PF-05231023 in diet-induced obese and leptin-deficient obese mice.
    Weng Y; Chabot JR; Bernardo B; Yan Q; Zhu Y; Brenner MB; Vage C; Logan A; Calle R; Talukdar S
    PLoS One; 2015; 10(3):e0119104. PubMed ID: 25790234
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Therapeutic effect of long-acting FGF21 with controlled site-specific modification on nonalcoholic steatohepatitis.
    Qi J; Guo Z; Zhu S; Jiang X; Wu Y; Chen Y; Hu F; Xiong J; Wu Y; Ye X; Liang X
    Int J Biol Macromol; 2024 Mar; 261(Pt 1):129797. PubMed ID: 38290625
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Pharmacokinetic and pharmacodynamic evaluation of site-specific PEGylated glucagon-like peptide-1 analogs as flexible postprandial-glucose controllers.
    Chae SY; Chun YG; Lee S; Jin CH; Lee ES; Lee KC; Youn YS
    J Pharm Sci; 2009 Apr; 98(4):1556-67. PubMed ID: 18704955
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Loss of fibroblast growth factor 21 action induces insulin resistance, pancreatic islet hyperplasia and dysfunction in mice.
    So WY; Cheng Q; Xu A; Lam KS; Leung PS
    Cell Death Dis; 2015 Mar; 6(3):e1707. PubMed ID: 25811804
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Fibroblast growth factor 21 mediates specific glucagon actions.
    Habegger KM; Stemmer K; Cheng C; Müller TD; Heppner KM; Ottaway N; Holland J; Hembree JL; Smiley D; Gelfanov V; Krishna R; Arafat AM; Konkar A; Belli S; Kapps M; Woods SC; Hofmann SM; D'Alessio D; Pfluger PT; Perez-Tilve D; Seeley RJ; Konishi M; Itoh N; Kharitonenkov A; Spranger J; DiMarchi RD; Tschöp MH
    Diabetes; 2013 May; 62(5):1453-63. PubMed ID: 23305646
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Metformin stimulates FGF21 expression in primary hepatocytes.
    Nygaard EB; Vienberg SG; Ørskov C; Hansen HS; Andersen B
    Exp Diabetes Res; 2012; 2012():465282. PubMed ID: 23118742
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.