654 related articles for article (PubMed ID: 22212137)
1. Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.
Zhang M; Deng Y; Luo Y; Zhang S; Zou H; Cai F; Wada K; Song W
J Neurochem; 2012 Mar; 120(6):1129-38. PubMed ID: 22212137
[TBL] [Abstract][Full Text] [Related]
2. The circular RNA ciRS-7 promotes APP and BACE1 degradation in an NF-κB-dependent manner.
Shi Z; Chen T; Yao Q; Zheng L; Zhang Z; Wang J; Hu Z; Cui H; Han Y; Han X; Zhang K; Hong W
FEBS J; 2017 Apr; 284(7):1096-1109. PubMed ID: 28296235
[TBL] [Abstract][Full Text] [Related]
3. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
4. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
[TBL] [Abstract][Full Text] [Related]
5. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
Kimura A; Hata S; Suzuki T
J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
[TBL] [Abstract][Full Text] [Related]
6. BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis.
Zhang S; Wang Z; Cai F; Zhang M; Wu Y; Zhang J; Song W
J Neurosci; 2017 Jul; 37(29):6915-6925. PubMed ID: 28626014
[TBL] [Abstract][Full Text] [Related]
7. Degradation of BACE by the ubiquitin-proteasome pathway.
Qing H; Zhou W; Christensen MA; Sun X; Tong Y; Song W
FASEB J; 2004 Oct; 18(13):1571-3. PubMed ID: 15289451
[TBL] [Abstract][Full Text] [Related]
8. CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of β-secretase.
Singh AK; Pati U
Aging Cell; 2015 Aug; 14(4):595-604. PubMed ID: 25773675
[TBL] [Abstract][Full Text] [Related]
9. Effects of BACE1 haploinsufficiency on APP processing and Aβ concentrations in male and female 5XFAD Alzheimer mice at different disease stages.
Devi L; Ohno M
Neuroscience; 2015 Oct; 307():128-37. PubMed ID: 26314636
[TBL] [Abstract][Full Text] [Related]
10. Overexpression of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) delays Alzheimer's progression in vivo.
Zhang M; Cai F; Zhang S; Zhang S; Song W
Sci Rep; 2014 Dec; 4():7298. PubMed ID: 25466238
[TBL] [Abstract][Full Text] [Related]
11. Cross-linking of cell surface amyloid precursor protein leads to increased β-amyloid peptide production in hippocampal neurons: implications for Alzheimer's disease.
Lefort R; Pozueta J; Shelanski M
J Neurosci; 2012 Aug; 32(31):10674-85. PubMed ID: 22855816
[TBL] [Abstract][Full Text] [Related]
12. Aβ1-42-mediated down-regulation of Uch-L1 is dependent on NF-κB activation and impaired BACE1 lysosomal degradation.
Guglielmotto M; Monteleone D; Boido M; Piras A; Giliberto L; Borghi R; Vercelli A; Fornaro M; Tabaton M; Tamagno E
Aging Cell; 2012 Oct; 11(5):834-44. PubMed ID: 22726800
[TBL] [Abstract][Full Text] [Related]
13. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
[TBL] [Abstract][Full Text] [Related]
14. Lys(203) and Lys(382) are essential for the proteasomal degradation of BACE1.
Wang R; Ying Z; Zhao J; Zhang Y; Wang R; Lu H; Deng Y; Song W; Qing H
Curr Alzheimer Res; 2012 Jun; 9(5):606-15. PubMed ID: 22299711
[TBL] [Abstract][Full Text] [Related]
15. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
Wu G; Sankaranarayanan S; Hsieh SH; Simon AJ; Savage MJ
J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
[TBL] [Abstract][Full Text] [Related]
16. The Endosome-associated Deubiquitinating Enzyme USP8 Regulates BACE1 Enzyme Ubiquitination and Degradation.
Yeates EF; Tesco G
J Biol Chem; 2016 Jul; 291(30):15753-66. PubMed ID: 27302062
[TBL] [Abstract][Full Text] [Related]
17. BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
Kim W; Ma L; Lomoio S; Willen R; Lombardo S; Dong J; Haydon PG; Tesco G
Mol Neurodegener; 2018 Feb; 13(1):6. PubMed ID: 29391027
[TBL] [Abstract][Full Text] [Related]
18. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
Chen LM; Lin ZY; Zhu YG; Lin N; Zhang J; Pan XD; Chen XC
Eur J Pharmacol; 2012 Jan; 675(1-3):15-21. PubMed ID: 22166376
[TBL] [Abstract][Full Text] [Related]
19. Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice.
Kimura R; Devi L; Ohno M
J Neurochem; 2010 Apr; 113(1):248-61. PubMed ID: 20089133
[TBL] [Abstract][Full Text] [Related]
20. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
Li S; Hou H; Mori T; Sawmiller D; Smith A; Tian J; Wang Y; Giunta B; Sanberg PR; Zhang S; Tan J
Sci Rep; 2015 Jun; 5():11322. PubMed ID: 26091071
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
