274 related articles for article (PubMed ID: 22216185)
1. Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1.
Grosso S; Pesce E; Brina D; Beugnet A; Loreni F; Biffo S
PLoS One; 2011; 6(12):e29136. PubMed ID: 22216185
[TBL] [Abstract][Full Text] [Related]
2. Vesicular stomatitis virus infection alters the eIF4F translation initiation complex and causes dephosphorylation of the eIF4E binding protein 4E-BP1.
Connor JH; Lyles DS
J Virol; 2002 Oct; 76(20):10177-87. PubMed ID: 12239292
[TBL] [Abstract][Full Text] [Related]
3. Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.
George A; Panda S; Kudmulwar D; Chhatbar SP; Nayak SC; Krishnan HH
J Biol Chem; 2012 Feb; 287(7):5042-58. PubMed ID: 22184107
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation.
Wang X; Yue P; Chan CB; Ye K; Ueda T; Watanabe-Fukunaga R; Fukunaga R; Fu H; Khuri FR; Sun SY
Mol Cell Biol; 2007 Nov; 27(21):7405-13. PubMed ID: 17724079
[TBL] [Abstract][Full Text] [Related]
5. The mTOR/4E-BP1/eIF4E Signalling Pathway as a Source of Cancer Drug Targets.
Maracci C; Motta S; Romagnoli A; Costantino M; Perego P; Di Marino D
Curr Med Chem; 2022; 29(20):3501-3529. PubMed ID: 35209811
[TBL] [Abstract][Full Text] [Related]
6. Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism.
Gingras AC; Gygi SP; Raught B; Polakiewicz RD; Abraham RT; Hoekstra MF; Aebersold R; Sonenberg N
Genes Dev; 1999 Jun; 13(11):1422-37. PubMed ID: 10364159
[TBL] [Abstract][Full Text] [Related]
7. Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma.
Demosthenous C; Han JJ; Stenson MJ; Maurer MJ; Wellik LE; Link B; Hege K; Dogan A; Sotomayor E; Witzig T; Gupta M
Oncotarget; 2015 Apr; 6(11):9488-501. PubMed ID: 25839159
[TBL] [Abstract][Full Text] [Related]
8. Monitoring flux in signalling pathways through measurements of 4EBP1-mediated eIF4F complex assembly.
Frosi Y; Usher R; Lian DTG; Lane DP; Brown CJ
BMC Biol; 2019 May; 17(1):40. PubMed ID: 31118010
[TBL] [Abstract][Full Text] [Related]
9. Phosphorylation dynamics of eukaryotic initiation factor 4E binding protein 1 (4E-BP1) is discordant with its potential to interact with eukaryotic initiation factor 4E (eIF4E).
Showkat M; Beigh MA; Bhat BB; Batool A; Andrabi KI
Cell Signal; 2014 Oct; 26(10):2117-21. PubMed ID: 24975846
[TBL] [Abstract][Full Text] [Related]
10. Inactivation of the mTORC1-eukaryotic translation initiation factor 4E pathway alters stress granule formation.
Fournier MJ; Coudert L; Mellaoui S; Adjibade P; Gareau C; Côté MF; Sonenberg N; Gaudreault RC; Mazroui R
Mol Cell Biol; 2013 Jun; 33(11):2285-301. PubMed ID: 23547259
[TBL] [Abstract][Full Text] [Related]
11. Blocking eukaryotic initiation factor 4F complex formation does not inhibit the mTORC1-dependent activation of protein synthesis in cardiomyocytes.
Huang BP; Wang Y; Wang X; Wang Z; Proud CG
Am J Physiol Heart Circ Physiol; 2009 Feb; 296(2):H505-14. PubMed ID: 19074679
[TBL] [Abstract][Full Text] [Related]
12. Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E.
Li Y; Yue P; Deng X; Ueda T; Fukunaga R; Khuri FR; Sun SY
Neoplasia; 2010 Oct; 12(10):848-55. PubMed ID: 20927323
[TBL] [Abstract][Full Text] [Related]
13. Eukaryotic Initiation Factor 4E (eIF4E) sequestration mediates 4E-BP1 response to rapamycin.
Batool A; Majeed ST; Aashaq S; Majeed R; Shah G; Nazir N; Andrabi KI
Int J Biol Macromol; 2019 Mar; 125():651-659. PubMed ID: 30552925
[TBL] [Abstract][Full Text] [Related]
14. 4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice.
Wang C; Cigliano A; Jiang L; Li X; Fan B; Pilo MG; Liu Y; Gui B; Sini M; Smith JW; Dombrowski F; Calvisi DF; Evert M; Chen X
Hepatology; 2015 Jan; 61(1):200-13. PubMed ID: 25145583
[TBL] [Abstract][Full Text] [Related]
15. Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer.
Satheesha S; Cookson VJ; Coleman LJ; Ingram N; Madhok B; Hanby AM; Suleman CA; Sabine VS; Macaskill EJ; Bartlett JM; Dixon JM; McElwaine JN; Hughes TA
Mol Cancer; 2011 Feb; 10():19. PubMed ID: 21320304
[TBL] [Abstract][Full Text] [Related]
16. Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells.
Bianchini A; Loiarro M; Bielli P; Busà R; Paronetto MP; Loreni F; Geremia R; Sette C
Carcinogenesis; 2008 Dec; 29(12):2279-88. PubMed ID: 18809972
[TBL] [Abstract][Full Text] [Related]
17. Phosphorylation of eIF4E by Mnk-1 enhances HSV-1 translation and replication in quiescent cells.
Walsh D; Mohr I
Genes Dev; 2004 Mar; 18(6):660-72. PubMed ID: 15075293
[TBL] [Abstract][Full Text] [Related]
18. Activation of p53 stimulates proteasome-dependent truncation of eIF4E-binding protein 1 (4E-BP1).
Constantinou C; Elia A; Clemens MJ
Biol Cell; 2008 May; 100(5):279-89. PubMed ID: 18021075
[TBL] [Abstract][Full Text] [Related]
19. Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.
Marzec M; Liu X; Wysocka M; Rook AH; Odum N; Wasik MA
PLoS One; 2011; 6(9):e24849. PubMed ID: 21949767
[TBL] [Abstract][Full Text] [Related]
20. The effect of p-4E-BP1 and p-eIF4E on cell proliferation in a breast cancer model.
Pons B; Peg V; Vázquez-Sánchez MA; López-Vicente L; Argelaguet E; Coch L; Martínez A; Hernández-Losa J; Armengol G; Ramon Y Cajal S
Int J Oncol; 2011 Nov; 39(5):1337-45. PubMed ID: 21750861
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]