100 related articles for article (PubMed ID: 22216435)
1. NrF2 ⁄Keap1 as gatekeepers of redox homeostasis – do they prevent or cause cancer?
Tew KD
Pigment Cell Melanoma Res; 2011 Dec; 24(6):1078-9. PubMed ID: 22216435
[No Abstract] [Full Text] [Related]
2. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
DeNicola GM; Karreth FA; Humpton TJ; Gopinathan A; Wei C; Frese K; Mangal D; Yu KH; Yeo CJ; Calhoun ES; Scrimieri F; Winter JM; Hruban RH; Iacobuzio-Donahue C; Kern SE; Blair IA; Tuveson DA
Nature; 2011 Jul; 475(7354):106-9. PubMed ID: 21734707
[TBL] [Abstract][Full Text] [Related]
3. Cancer: when antioxidants are bad.
Perera RM; Bardeesy N
Nature; 2011 Jul; 475(7354):43-4. PubMed ID: 21734699
[No Abstract] [Full Text] [Related]
4. Hypermethylation of the Keap1 gene inactivates its function, promotes Nrf2 nuclear accumulation, and is involved in arsenite-induced human keratinocyte transformation.
Wang D; Ma Y; Yang X; Xu X; Zhao Y; Zhu Z; Wang X; Deng H; Li C; Gao F; Tong J; Yamanaka K; An Y
Free Radic Biol Med; 2015 Dec; 89():209-19. PubMed ID: 26409248
[TBL] [Abstract][Full Text] [Related]
5. NRF2: Translating the Redox Code.
Tummala KS; Kottakis F; Bardeesy N
Trends Mol Med; 2016 Oct; 22(10):829-831. PubMed ID: 27555347
[TBL] [Abstract][Full Text] [Related]
6. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis.
Stępkowski TM; Kruszewski MK
Free Radic Biol Med; 2011 May; 50(9):1186-95. PubMed ID: 21295136
[TBL] [Abstract][Full Text] [Related]
7. Keap1-Nrf2 signalling in pancreatic cancer.
Hayes AJ; Skouras C; Haugk B; Charnley RM
Int J Biochem Cell Biol; 2015 Aug; 65():288-99. PubMed ID: 26117456
[TBL] [Abstract][Full Text] [Related]
8. The Relevance of Nrf2 Pathway and Autophagy in Pancreatic Cancer Cells upon Stimulation of Reactive Oxygen Species.
Zhang L; Li J; Ma J; Chen X; Chen K; Jiang Z; Zong L; Yu S; Li X; Xu Q; Lei J; Duan W; Li W; Shan T; Ma Q; Shen X
Oxid Med Cell Longev; 2016; 2016():3897250. PubMed ID: 26682003
[TBL] [Abstract][Full Text] [Related]
9. The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells -Nrf2 as determinant of pro-tumorigenic functions of TGF-β1.
Genrich G; Kruppa M; Lenk L; Helm O; Broich A; Freitag-Wolf S; Röcken C; Sipos B; Schäfer H; Sebens S
BMC Cancer; 2016 Feb; 16():155. PubMed ID: 26915435
[TBL] [Abstract][Full Text] [Related]
10. Continuous activation of Nrf2 and its target antioxidant enzymes leads to arsenite-induced malignant transformation of human bronchial epithelial cells.
Yang X; Wang D; Ma Y; Xu X; Zhu Z; Wang X; Deng H; Li C; Chen M; Tong J; Yamanaka K; An Y
Toxicol Appl Pharmacol; 2015 Dec; 289(2):231-9. PubMed ID: 26420645
[TBL] [Abstract][Full Text] [Related]
11. Regulation of the Nrf2 antioxidant pathway by microRNAs: New players in micromanaging redox homeostasis.
Cheng X; Ku CH; Siow RC
Free Radic Biol Med; 2013 Sep; 64():4-11. PubMed ID: 23880293
[TBL] [Abstract][Full Text] [Related]
12. The role of the Nrf2/Keap1 pathway in obesity and metabolic syndrome.
Zhang Z; Zhou S; Jiang X; Wang YH; Li F; Wang YG; Zheng Y; Cai L
Rev Endocr Metab Disord; 2015 Mar; 16(1):35-45. PubMed ID: 25540093
[TBL] [Abstract][Full Text] [Related]
13. Soluble factors from stellate cells induce pancreatic cancer cell proliferation via Nrf2-activated metabolic reprogramming and ROS detoxification.
Wu YS; Looi CY; Subramaniam KS; Masamune A; Chung I
Oncotarget; 2016 Jun; 7(24):36719-36732. PubMed ID: 27167341
[TBL] [Abstract][Full Text] [Related]
14. Restoration of Nrf2 Signaling Normalizes the Regenerative Niche.
Soares MA; Cohen OD; Low YC; Sartor RA; Ellison T; Anil U; Anzai L; Chang JB; Saadeh PB; Rabbani PS; Ceradini DJ
Diabetes; 2016 Mar; 65(3):633-46. PubMed ID: 26647385
[TBL] [Abstract][Full Text] [Related]
15. ERK inhibition sensitizes cancer cells to oleanolic acid-induced apoptosis through ERK/Nrf2/ROS pathway.
Liu J; Ma L; Chen X; Wang J; Yu T; Gong Y; Ma A; Zheng L; Liang H
Tumour Biol; 2016 Jun; 37(6):8181-7. PubMed ID: 26715278
[TBL] [Abstract][Full Text] [Related]
16. The intricacies of NRF2 regulation in cancer.
Schmidlin CJ; Shakya A; Dodson M; Chapman E; Zhang DD
Semin Cancer Biol; 2021 Nov; 76():110-119. PubMed ID: 34020028
[TBL] [Abstract][Full Text] [Related]
17. Toward clinical application of the Keap1-Nrf2 pathway.
Suzuki T; Motohashi H; Yamamoto M
Trends Pharmacol Sci; 2013 Jun; 34(6):340-6. PubMed ID: 23664668
[TBL] [Abstract][Full Text] [Related]
18. Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cells.
Roy RV; Pratheeshkumar P; Son YO; Wang L; Hitron JA; Divya SP; Zhang Z; Shi X
Toxicol Appl Pharmacol; 2016 Sep; 307():81-90. PubMed ID: 27470422
[TBL] [Abstract][Full Text] [Related]
19. The gasotransmitter hydrogen sulfide induces nrf2-target genes by inactivating the keap1 ubiquitin ligase substrate adaptor through formation of a disulfide bond between cys-226 and cys-613.
Hourihan JM; Kenna JG; Hayes JD
Antioxid Redox Signal; 2013 Aug; 19(5):465-81. PubMed ID: 23145493
[TBL] [Abstract][Full Text] [Related]
20. ROS in translation: Chink in the armor.
Chio II; Tuveson DA
Cell Cycle; 2017 Feb; 16(4):297-298. PubMed ID: 27636545
[No Abstract] [Full Text] [Related]
[Next] [New Search]