BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

785 related articles for article (PubMed ID: 22219182)

  • 1. Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment.
    Pan MR; Hsieh HJ; Dai H; Hung WC; Li K; Peng G; Lin SY
    J Biol Chem; 2012 Feb; 287(9):6764-72. PubMed ID: 22219182
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Acetyltransferase p300 collaborates with chromodomain helicase DNA-binding protein 4 (CHD4) to facilitate DNA double-strand break repair.
    Qi W; Chen H; Xiao T; Wang R; Li T; Han L; Zeng X
    Mutagenesis; 2016 Mar; 31(2):193-203. PubMed ID: 26546801
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The N-terminal Region of Chromodomain Helicase DNA-binding Protein 4 (CHD4) Is Essential for Activity and Contains a High Mobility Group (HMG) Box-like-domain That Can Bind Poly(ADP-ribose).
    Silva AP; Ryan DP; Galanty Y; Low JK; Vandevenne M; Jackson SP; Mackay JP
    J Biol Chem; 2016 Jan; 291(2):924-38. PubMed ID: 26565020
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4.
    Polo SE; Kaidi A; Baskcomb L; Galanty Y; Jackson SP
    EMBO J; 2010 Sep; 29(18):3130-9. PubMed ID: 20693977
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair.
    Wiltshire TD; Lovejoy CA; Wang T; Xia F; O'Connor MJ; Cortez D
    J Biol Chem; 2010 May; 285(19):14565-71. PubMed ID: 20233726
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination-deficient cells.
    Verma P; Zhou Y; Cao Z; Deraska PV; Deb M; Arai E; Li W; Shao Y; Puentes L; Li Y; Patankar S; Mach RH; Faryabi RB; Shi J; Greenberg RA
    Nat Cell Biol; 2021 Feb; 23(2):160-171. PubMed ID: 33462394
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The NuRD complex-mediated p21 suppression facilitates chemoresistance in BRCA-proficient breast cancer.
    Hou MF; Luo CW; Chang TM; Hung WC; Chen TY; Tsai YL; Chai CY; Pan MR
    Exp Cell Res; 2017 Oct; 359(2):458-465. PubMed ID: 28842166
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage.
    Larsen DH; Poinsignon C; Gudjonsson T; Dinant C; Payne MR; Hari FJ; Rendtlew Danielsen JM; Menard P; Sand JC; Stucki M; Lukas C; Bartek J; Andersen JS; Lukas J
    J Cell Biol; 2010 Sep; 190(5):731-40. PubMed ID: 20805324
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition.
    Cavallo F; Graziani G; Antinozzi C; Feldman DR; Houldsworth J; Bosl GJ; Chaganti RS; Moynahan ME; Jasin M; Barchi M
    PLoS One; 2012; 7(12):e51563. PubMed ID: 23251575
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA damage response pathways in tumor suppression and cancer treatment.
    Liang Y; Lin SY; Brunicardi FC; Goss J; Li K
    World J Surg; 2009 Apr; 33(4):661-6. PubMed ID: 19034564
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthetic lethality between BRCA1 deficiency and poly(ADP-ribose) polymerase inhibition is modulated by processing of endogenous oxidative DNA damage.
    Giovannini S; Weller MC; Repmann S; Moch H; Jiricny J
    Nucleic Acids Res; 2019 Sep; 47(17):9132-9143. PubMed ID: 31329989
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [From poly(ADP-ribose) discovery to PARP inhibitors in cancer therapy].
    Schreiber V; Illuzzi G; Héberlé E; Dantzer F
    Bull Cancer; 2015 Oct; 102(10):863-73. PubMed ID: 26384693
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage.
    Chou DM; Adamson B; Dephoure NE; Tan X; Nottke AC; Hurov KE; Gygi SP; Colaiácovo MP; Elledge SJ
    Proc Natl Acad Sci U S A; 2010 Oct; 107(43):18475-80. PubMed ID: 20937877
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Poly (ADP-ribose) polymerase inhibitors selectively induce cytotoxicity in TCF3-HLF-positive leukemic cells.
    Piao J; Takai S; Kamiya T; Inukai T; Sugita K; Ohyashiki K; Delia D; Masutani M; Mizutani S; Takagi M
    Cancer Lett; 2017 Feb; 386():131-140. PubMed ID: 27894958
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CHD3 and CHD4 recruitment and chromatin remodeling activity at DNA breaks is promoted by early poly(ADP-ribose)-dependent chromatin relaxation.
    Smith R; Sellou H; Chapuis C; Huet S; Timinszky G
    Nucleic Acids Res; 2018 Jul; 46(12):6087-6098. PubMed ID: 29733391
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials.
    Yuan B; Ye N; Song SS; Wang YT; Song Z; Chen HD; Chen CH; Huan XJ; Wang YQ; Su Y; Shen YY; Sun YM; Yang XY; Chen Y; Guo SY; Gan Y; Gao ZW; Chen XY; Ding J; He JX; Zhang A; Miao ZH
    Cancer Lett; 2017 Feb; 386():47-56. PubMed ID: 27847302
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p21CDKN1A Regulates the Binding of Poly(ADP-Ribose) Polymerase-1 to DNA Repair Intermediates.
    Dutto I; Sukhanova M; Tillhon M; Cazzalini O; Stivala LA; Scovassi AI; Lavrik O; Prosperi E
    PLoS One; 2016; 11(1):e0146031. PubMed ID: 26730949
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An insight into understanding the coupling between homologous recombination mediated DNA repair and chromatin remodeling mechanisms in plant genome: an update.
    Banerjee S; Roy S
    Cell Cycle; 2021 Sep; 20(18):1760-1784. PubMed ID: 34437813
    [TBL] [Abstract][Full Text] [Related]  

  • 19. WIP1 Promotes Homologous Recombination and Modulates Sensitivity to PARP Inhibitors.
    Burdova K; Storchova R; Palek M; Macurek L
    Cells; 2019 Oct; 8(10):. PubMed ID: 31619012
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks.
    Krietsch J; Caron MC; Gagné JP; Ethier C; Vignard J; Vincent M; Rouleau M; Hendzel MJ; Poirier GG; Masson JY
    Nucleic Acids Res; 2012 Nov; 40(20):10287-301. PubMed ID: 22941645
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 40.