BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 22223484)

  • 1. Protein phosphatase 2A regulates innate immune and proteolytic responses to cigarette smoke exposure in the lung.
    Wallace AM; Hardigan A; Geraghty P; Salim S; Gaffney A; Thankachen J; Arellanos L; D'Armiento JM; Foronjy RF
    Toxicol Sci; 2012 Apr; 126(2):589-99. PubMed ID: 22223484
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The glutathione peroxidase 1-protein tyrosine phosphatase 1B-protein phosphatase 2A axis. A key determinant of airway inflammation and alveolar destruction.
    Geraghty P; Hardigan AA; Wallace AM; Mirochnitchenko O; Thankachen J; Arellanos L; Thompson V; D'Armiento JM; Foronjy RF
    Am J Respir Cell Mol Biol; 2013 Nov; 49(5):721-30. PubMed ID: 23590304
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein Phosphatase 2A Reduces Cigarette Smoke-induced Cathepsin S and Loss of Lung Function.
    Doherty DF; Nath S; Poon J; Foronjy RF; Ohlmeyer M; Dabo AJ; Salathe M; Birrell M; Belvisi M; Baumlin N; Kim MD; Weldon S; Taggart C; Geraghty P
    Am J Respir Crit Care Med; 2019 Jul; 200(1):51-62. PubMed ID: 30641028
    [No Abstract]   [Full Text] [Related]  

  • 4. Chronic Cigarette Smoke Exposure Subdues PP2A Activity by Enhancing Expression of the Oncogene CIP2A.
    Nath S; Ohlmeyer M; Salathe MA; Poon J; Baumlin N; Foronjy RF; Geraghty P
    Am J Respir Cell Mol Biol; 2018 Dec; 59(6):695-705. PubMed ID: 30011381
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cigarette smoke activates the proto-oncogene c-src to promote airway inflammation and lung tissue destruction.
    Geraghty P; Hardigan A; Foronjy RF
    Am J Respir Cell Mol Biol; 2014 Mar; 50(3):559-70. PubMed ID: 24111605
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Respiratory syncytial virus infections enhance cigarette smoke induced COPD in mice.
    Foronjy RF; Dabo AJ; Taggart CC; Weldon S; Geraghty P
    PLoS One; 2014; 9(2):e90567. PubMed ID: 24587397
    [TBL] [Abstract][Full Text] [Related]  

  • 7. α1-Antitrypsin activates protein phosphatase 2A to counter lung inflammatory responses.
    Geraghty P; Eden E; Pillai M; Campos M; McElvaney NG; Foronjy RF
    Am J Respir Crit Care Med; 2014 Dec; 190(11):1229-42. PubMed ID: 25341065
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evaluating Novel Protein Phosphatase 2A Activators as Therapeutics for Emphysema.
    Soto B; Ahmed H; Pillai M; Park SS; Ploszaj M; Reece J; Taluru H; Bobrow D; Yu H; Lafortune P; Jundi B; Costanzo L; Dabo AJ; Foronjy RF; Mueller C; Ohlmeyer M; Geraghty P
    Am J Respir Cell Mol Biol; 2023 Nov; 69(5):533-544. PubMed ID: 37526463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of the unfolded protein response by cigarette smoke is primarily an activating transcription factor 4-C/EBP homologous protein mediated process.
    Geraghty P; Wallace A; D'Armiento JM
    Int J Chron Obstruct Pulmon Dis; 2011; 6():309-19. PubMed ID: 21697995
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cigarette smoke-induced autophagy impairment accelerates lung aging, COPD-emphysema exacerbations and pathogenesis.
    Vij N; Chandramani-Shivalingappa P; Van Westphal C; Hole R; Bodas M
    Am J Physiol Cell Physiol; 2018 Jan; 314(1):C73-C87. PubMed ID: 27413169
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TLR9 expression is required for the development of cigarette smoke-induced emphysema in mice.
    Foronjy RF; Salathe MA; Dabo AJ; Baumlin N; Cummins N; Eden E; Geraghty P
    Am J Physiol Lung Cell Mol Physiol; 2016 Jul; 311(1):L154-66. PubMed ID: 27288485
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nitrogen dioxide exposure attenuates cigarette smoke-induced cytokine production in mice.
    Brandsma CA; Hylkema MN; Luinge MA; Geerlings M; Klok PA; Cassee FR; Timens W; Postma DS; Kerstjens HA
    Inhal Toxicol; 2008 Jan; 20(2):183-9. PubMed ID: 18236232
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lung epithelial CCAAT/enhancer-binding protein-β is necessary for the integrity of inflammatory responses to cigarette smoke.
    Didon L; Barton JL; Roos AB; Gaschler GJ; Bauer CM; Berg T; Stämpfli MR; Nord M
    Am J Respir Crit Care Med; 2011 Jul; 184(2):233-42. PubMed ID: 21562127
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MTOR Suppresses Cigarette Smoke-Induced Epithelial Cell Death and Airway Inflammation in Chronic Obstructive Pulmonary Disease.
    Wang Y; Liu J; Zhou JS; Huang HQ; Li ZY; Xu XC; Lai TW; Hu Y; Zhou HB; Chen HP; Ying SM; Li W; Shen HH; Chen ZH
    J Immunol; 2018 Apr; 200(8):2571-2580. PubMed ID: 29507104
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rapamycin attenuates Tc1 and Tc17 cell responses in cigarette smoke-induced emphysema in mice.
    Zhang H; Zhou X; Chen X; Lin Y; Qiu S; Zhao Y; Tang Q; Liang Y; Zhong X
    Inflamm Res; 2019 Nov; 68(11):957-968. PubMed ID: 31468083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Klotho expression is reduced in COPD airway epithelial cells: effects on inflammation and oxidant injury.
    Gao W; Yuan C; Zhang J; Li L; Yu L; Wiegman CH; Barnes PJ; Adcock IM; Huang M; Yao X
    Clin Sci (Lond); 2015 Dec; 129(12):1011-23. PubMed ID: 26201096
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mice overexpressing latent matrix metalloproteinase-2 develop lung emphysema after short-term exposure to cigarette smoke extract.
    Onishi M; Kobayashi T; D'Alessandro-Gabazza CN; Fujimoto H; Chelakkot-Govindalayathil AL; Takahashi Y; Yasuma T; Nishihama K; Toda M; Takei Y; Taguchi O; Gabazza EC
    Biochem Biophys Res Commun; 2018 Feb; 497(1):332-338. PubMed ID: 29428733
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Master Autophagy Regulator Transcription Factor EB Regulates Cigarette Smoke-Induced Autophagy Impairment and Chronic Obstructive Pulmonary Disease-Emphysema Pathogenesis.
    Bodas M; Patel N; Silverberg D; Walworth K; Vij N
    Antioxid Redox Signal; 2017 Jul; 27(3):150-167. PubMed ID: 27835930
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MicroRNA-150 protects against cigarette smoke-induced lung inflammation and airway epithelial cell apoptosis through repressing p53: MicroRNA-150 in CS-induced lung inflammation.
    Xue H; Li MX
    Hum Exp Toxicol; 2018 Sep; 37(9):920-928. PubMed ID: 29205062
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diminished stimulator of interferon genes production with cigarette smoke-exposure contributes to weakened anti-adenovirus vectors response and destruction of lung in chronic obstructive pulmonary disease model.
    Qin H; Huang G; Gao F; Huang B; Wang D; Hu X; Wang Y; Peng L; Luo D; Mo B; Hu C; Li Y; Wang C
    Exp Cell Res; 2019 Nov; 384(1):111545. PubMed ID: 31470016
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.