These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 22225639)

  • 1. Synthesis of 3-phenylsulfonylmethyl cyclohexylaminobenzamide-derived antagonists of CC chemokine receptor 2 (CCR2).
    Yang MG; Xiao Z; Shi Q; Cherney RJ; Tebben AJ; De Lucca GV; Santella JB; Mo R; Cvijic ME; Zhao Q; Barrish JC; Carter PH
    Bioorg Med Chem Lett; 2012 Feb; 22(3):1384-7. PubMed ID: 22225639
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and evaluation of cis-3,4-disubstituted piperidines as potent CC chemokine receptor 2 (CCR2) antagonists.
    Cherney RJ; Nelson DJ; Lo YC; Yang G; Scherle PA; Jezak H; Solomon KA; Carter PH; Decicco CP
    Bioorg Med Chem Lett; 2008 Sep; 18(18):5063-5. PubMed ID: 18722120
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and structure-activity relationship of 7-azaindole piperidine derivatives as CCR2 antagonists.
    Xia M; Hou C; DeMong D; Pollack S; Pan M; Singer M; Matheis M; Murray W; Cavender D; Wachter M
    Bioorg Med Chem Lett; 2008 Dec; 18(24):6468-70. PubMed ID: 18990568
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of trisubstituted cyclohexanes as potent CC chemokine receptor 2 (CCR2) antagonists.
    Cherney RJ; Brogan JB; Mo R; Lo YC; Yang G; Miller PB; Scherle PA; Molino BF; Carter PH; Decicco CP
    Bioorg Med Chem Lett; 2009 Feb; 19(3):597-601. PubMed ID: 19131247
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 3-Amino-1-alkyl-cyclopentane carboxamides as small molecule antagonists of the human and murine CC chemokine receptor 2.
    Butora G; Jiao R; Parsons WH; Vicario PP; Jin H; Ayala JM; Cascieri MA; Yang L
    Bioorg Med Chem Lett; 2007 Jul; 17(13):3636-41. PubMed ID: 17482462
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substituted dipiperidine alcohols as potent CCR2 antagonists.
    Xia M; Hou C; Demong D; Pollack S; Pan M; Brackley J; Singer M; Matheis M; Cavender D; Wachter M
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3562-4. PubMed ID: 18487045
    [TBL] [Abstract][Full Text] [Related]  

  • 7. QSAR studies on CCR2 antagonists with chiral sensitive hologram descriptors.
    Nair PC; Srikanth K; Sobhia ME
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1323-30. PubMed ID: 18258426
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of 3-aminopyrrolidine derivatives as CC chemokine receptor 2 antagonists.
    Lim JW; Oh Y; Kim JH; Oak MH; Na Y; Lee JO; Lee SW; Cho H; Park WK; Choi G; Kang J
    Bioorg Med Chem Lett; 2010 Apr; 20(7):2099-102. PubMed ID: 20223662
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of 3-piperidinyl-1-cyclopentanecarboxamide as a novel scaffold for highly potent CC chemokine receptor 2 antagonists.
    Yang L; Butora G; Jiao RX; Pasternak A; Zhou C; Parsons WH; Mills SG; Vicario PP; Ayala JM; Cascieri MA; MacCoss M
    J Med Chem; 2007 May; 50(11):2609-11. PubMed ID: 17461566
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel, orally bioavailable gamma-aminoamide CC chemokine receptor 2 (CCR2) antagonists.
    Pasternak A; Marino D; Vicario PP; Ayala JM; Cascierri MA; Parsons W; Mills SG; Maccoss M; Yang L
    J Med Chem; 2006 Aug; 49(16):4801-4. PubMed ID: 16884289
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The discovery of novel cyclohexylamide CCR2 antagonists.
    Lanter JC; Markotan TP; Zhang X; Subasinghe N; Kang FA; Hou C; Singer M; Opas E; McKenney S; Crysler C; Johnson D; Molloy CJ; Sui Z
    Bioorg Med Chem Lett; 2011 Dec; 21(24):7496-501. PubMed ID: 22061641
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Benzimidazoles as benzamide replacements within cyclohexane-based CC chemokine receptor 2 (CCR2) antagonists.
    Cherney RJ; Mo R; Meyer DT; Pechulis AD; Guaciaro MA; Lo YC; Yang G; Miller PB; Scherle PA; Zhao Q; Cvijic ME; Barrish JC; Decicco CP; Carter PH
    Bioorg Med Chem Lett; 2012 Oct; 22(19):6181-4. PubMed ID: 22939233
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5.
    Hall SE; Mao A; Nicolaidou V; Finelli M; Wise EL; Nedjai B; Kanjanapangka J; Harirchian P; Chen D; Selchau V; Ribeiro S; Schyler S; Pease JE; Horuk R; Vaidehi N
    Mol Pharmacol; 2009 Jun; 75(6):1325-36. PubMed ID: 19297521
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and structure-activity relationship of novel CCR2 antagonists.
    Kothandaraman S; Donnely KL; Butora G; Jiao R; Pasternak A; Morriello GJ; Goble SD; Zhou C; Mills SG; Maccoss M; Vicario PP; Ayala JM; Demartino JA; Struthers M; Cascieri MA; Yang L
    Bioorg Med Chem Lett; 2009 Mar; 19(6):1830-4. PubMed ID: 19237282
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of disubstituted cyclohexanes as a new class of CC chemokine receptor 2 antagonists.
    Cherney RJ; Mo R; Meyer DT; Nelson DJ; Lo YC; Yang G; Scherle PA; Mandlekar S; Wasserman ZR; Jezak H; Solomon KA; Tebben AJ; Carter PH; Decicco CP
    J Med Chem; 2008 Feb; 51(4):721-4. PubMed ID: 18232650
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Capped diaminopropionamide-glycine dipeptides are inhibitors of CC chemokine receptor 2 (CCR2).
    Carter PH; Brown GD; Friedrich SR; Cherney RJ; Tebben AJ; Lo YC; Yang G; Jezak H; Solomon KA; Scherle PA; Decicco CP
    Bioorg Med Chem Lett; 2007 Oct; 17(19):5455-61. PubMed ID: 17720492
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New indole amide derivatives as potent CRTH2 receptor antagonists.
    Zaghdane H; Boyd M; Colucci J; Simard D; Berthelette C; Leblanc Y; Wang Z; Houle R; Lévesque JF; Molinaro C; Hamel M; Stocco R; Sawyer N; Sillaots S; Gervais F; Gallant M
    Bioorg Med Chem Lett; 2011 Jun; 21(11):3471-4. PubMed ID: 21515053
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists.
    Xia M; Hou C; DeMong DE; Pollack SR; Pan M; Brackley JA; Jain N; Gerchak C; Singer M; Malaviya R; Matheis M; Olini G; Cavender D; Wachter M
    J Med Chem; 2007 Nov; 50(23):5561-3. PubMed ID: 17929797
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of novel CCR2 antagonists: investigation of non-aryl/heteroaryl binding motifs.
    Trujillo JI; Huang W; Hughes RO; Rogier DJ; Turner SR; Devraj R; Morton PA; Xue CB; Chao G; Covington MB; Newton RC; Metcalf B
    Bioorg Med Chem Lett; 2011 Mar; 21(6):1827-31. PubMed ID: 21316220
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of small molecule human C5a receptor antagonists.
    Sanganee HJ; Baxter A; Barber S; Brown AJ; Grice D; Hunt F; King S; Laughton D; Pairaudeau G; Thong B; Weaver R; Unitt J
    Bioorg Med Chem Lett; 2009 Feb; 19(4):1143-7. PubMed ID: 19171482
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.