BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

759 related articles for article (PubMed ID: 22225988)

  • 1. Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer.
    Schwab LP; Peacock DL; Majumdar D; Ingels JF; Jensen LC; Smith KD; Cushing RC; Seagroves TN
    Breast Cancer Res; 2012 Jan; 14(1):R6. PubMed ID: 22225988
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ITGA6 is directly regulated by hypoxia-inducible factors and enriches for cancer stem cell activity and invasion in metastatic breast cancer models.
    Brooks DL; Schwab LP; Krutilina R; Parke DN; Sethuraman A; Hoogewijs D; Schörg A; Gotwald L; Fan M; Wenger RH; Seagroves TN
    Mol Cancer; 2016 Mar; 15():26. PubMed ID: 27001172
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The antioxidant N-acetylcysteine prevents HIF-1 stabilization under hypoxia in vitro but does not affect tumorigenesis in multiple breast cancer models in vivo.
    Sceneay J; Liu MC; Chen A; Wong CS; Bowtell DD; Möller A
    PLoS One; 2013; 8(6):e66388. PubMed ID: 23840457
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fluorescence-Activated Cell Sorting of Murine Mammary Cancer Stem-Like Cell Subpopulations with HIF Activity.
    Brooks DL; Seagroves TN
    Methods Mol Biol; 2018; 1742():247-263. PubMed ID: 29330806
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.
    Liao D; Corle C; Seagroves TN; Johnson RS
    Cancer Res; 2007 Jan; 67(2):563-72. PubMed ID: 17234764
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers.
    Weng D; Penzner JH; Song B; Koido S; Calderwood SK; Gong J
    Breast Cancer Res; 2012 Jan; 14(1):R18. PubMed ID: 22277639
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxia induces tumor aggressiveness and the expansion of CD133-positive cells in a hypoxia-inducible factor-1α-dependent manner in pancreatic cancer cells.
    Hashimoto O; Shimizu K; Semba S; Chiba S; Ku Y; Yokozaki H; Hori Y
    Pathobiology; 2011; 78(4):181-92. PubMed ID: 21778785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. β-glucan from Lentinus edodes inhibits breast cancer progression via the Nur77/HIF-1α axis.
    Zhang X; Li T; Liu S; Xu Y; Meng M; Li X; Lin Z; Wu Q; Xue Y; Pan Y; Alitongbieke G
    Biosci Rep; 2020 Dec; 40(12):. PubMed ID: 33245358
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth.
    Mao SPH; Park M; Cabrera RM; Christin JR; Karagiannis GS; Oktay MH; Zaiss DMW; Abrams SI; Guo W; Condeelis JS; Kenny PA; Segall JE
    Breast Cancer Res; 2018 Oct; 20(1):131. PubMed ID: 30367629
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transformation of enriched mammary cell populations with polyomavirus middle T antigen influences tumor subtype and metastatic potential.
    Drobysheva D; Smith BA; McDowell M; Guillen KP; Ekiz HA; Welm BE
    Breast Cancer Res; 2015 Oct; 17(1):132. PubMed ID: 26429062
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MicroRNA-18a inhibits hypoxia-inducible factor 1α activity and lung metastasis in basal breast cancers.
    Krutilina R; Sun W; Sethuraman A; Brown M; Seagroves TN; Pfeffer LM; Ignatova T; Fan M
    Breast Cancer Res; 2014 Jul; 16(4):R78. PubMed ID: 25069832
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HEXIM1 modulates vascular endothelial growth factor expression and function in breast epithelial cells and mammary gland.
    Ogba N; Doughman YQ; Chaplin LJ; Hu Y; Gargesha M; Watanabe M; Montano MM
    Oncogene; 2010 Jun; 29(25):3639-49. PubMed ID: 20453883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Effects of hypoxia inducible factor-1α on P311 and its influence on the migration of murine epidermal stem cells].
    Xu ZD; Li HS; Wang S; He WF; Wu J; Luo GX
    Zhonghua Shao Shang Za Zhi; 2017 May; 33(5):287-294. PubMed ID: 28651420
    [No Abstract]   [Full Text] [Related]  

  • 14. Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity.
    Cicchini M; Chakrabarti R; Kongara S; Price S; Nahar R; Lozy F; Zhong H; Vazquez A; Kang Y; Karantza V
    Autophagy; 2014; 10(11):2036-52. PubMed ID: 25483966
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proteolysis-a characteristic of tumor-initiating cells in murine metastatic breast cancer.
    Hillebrand LE; Bengsch F; Hochrein J; Hülsdünker J; Bender J; Follo M; Busch H; Boerries M; Reinheckel T
    Oncotarget; 2016 Sep; 7(36):58244-58260. PubMed ID: 27542270
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Upregulation of autophagy by hypoxia-inducible factor-1α promotes EMT and metastatic ability of CD133+ pancreatic cancer stem-like cells during intermittent hypoxia.
    Zhu H; Wang D; Zhang L; Xie X; Wu Y; Liu Y; Shao G; Su Z
    Oncol Rep; 2014 Sep; 32(3):935-42. PubMed ID: 24994549
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Yap1 promotes the survival and self-renewal of breast tumor initiating cells via inhibiting Smad3 signaling.
    Sun JG; Chen XW; Zhang LP; Wang J; Diehn M
    Oncotarget; 2016 Mar; 7(9):9692-706. PubMed ID: 26695440
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HIF-1α induces the epithelial-mesenchymal transition in gastric cancer stem cells through the Snail pathway.
    Yang SW; Zhang ZG; Hao YX; Zhao YL; Qian F; Shi Y; Li PA; Liu CY; Yu PW
    Oncotarget; 2017 Feb; 8(6):9535-9545. PubMed ID: 28076840
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of HIF1A From Pancreatic Cancer Cells Increases Expression of PPP1R1B and Degradation of p53 to Promote Invasion and Metastasis.
    Tiwari A; Tashiro K; Dixit A; Soni A; Vogel K; Hall B; Shafqat I; Slaughter J; Param N; Le A; Saunders E; Paithane U; Garcia G; Campos AR; Zettervall J; Carlson M; Starr TK; Marahrens Y; Deshpande AJ; Commisso C; Provenzano PP; Bagchi A
    Gastroenterology; 2020 Nov; 159(5):1882-1897.e5. PubMed ID: 32768595
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma.
    Zhang M; Zhang W; Wu Z; Liu S; Sun L; Zhong Y; Zhang X; Kong X; Qian P; Zhang H; Lobie PE; Zhu T
    Oncotarget; 2016 Jan; 7(3):3267-82. PubMed ID: 26675549
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 38.