267 related articles for article (PubMed ID: 22230199)
21. Methods for the elucidation of protein-small molecule interactions.
McFedries A; Schwaid A; Saghatelian A
Chem Biol; 2013 May; 20(5):667-73. PubMed ID: 23706633
[TBL] [Abstract][Full Text] [Related]
22. Experiences in fragment-based lead discovery.
Hubbard RE; Murray JB
Methods Enzymol; 2011; 493():509-31. PubMed ID: 21371604
[TBL] [Abstract][Full Text] [Related]
23. Ligand discovery using small-molecule microarrays.
Casalena DE; Wassaf D; Koehler AN
Methods Mol Biol; 2012; 803():249-63. PubMed ID: 22065230
[TBL] [Abstract][Full Text] [Related]
24. Importance of molecular computer modeling in anticancer drug development.
Geromichalos GD
J BUON; 2007 Sep; 12 Suppl 1():S101-18. PubMed ID: 17935268
[TBL] [Abstract][Full Text] [Related]
25. Recent discoveries and applications involving small-molecule microarrays.
Hong JA; Neel DV; Wassaf D; Caballero F; Koehler AN
Curr Opin Chem Biol; 2014 Feb; 18():21-8. PubMed ID: 24534749
[TBL] [Abstract][Full Text] [Related]
26. [The application of small molecule bioactive probes in the identification of cellular targets].
Zhang J; Zhou HC
Yao Xue Xue Bao; 2012 Mar; 47(3):299-306. PubMed ID: 22645752
[TBL] [Abstract][Full Text] [Related]
27. Structure-based druggability assessment--identifying suitable targets for small molecule therapeutics.
Fauman EB; Rai BK; Huang ES
Curr Opin Chem Biol; 2011 Aug; 15(4):463-8. PubMed ID: 21704549
[TBL] [Abstract][Full Text] [Related]
28. Native Mass Spectrometry in Fragment-Based Drug Discovery.
Pedro L; Quinn RJ
Molecules; 2016 Jul; 21(8):. PubMed ID: 27483215
[TBL] [Abstract][Full Text] [Related]
29. Drug discovery with DNA-encoded chemical libraries.
Buller F; Mannocci L; Scheuermann J; Neri D
Bioconjug Chem; 2010 Sep; 21(9):1571-80. PubMed ID: 20681509
[TBL] [Abstract][Full Text] [Related]
30. Fragment-based ligand discovery.
Fischer M; Hubbard RE
Mol Interv; 2009 Feb; 9(1):22-30. PubMed ID: 19299661
[TBL] [Abstract][Full Text] [Related]
31. Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC.
Ong SE; Li X; Schenone M; Schreiber SL; Carr SA
Methods Mol Biol; 2012; 803():129-40. PubMed ID: 22065222
[TBL] [Abstract][Full Text] [Related]
32. Identification of peptide substrate and small molecule inhibitors of testis-specific serine/threonine kinase1 (TSSK1) by the developed assays.
Zhang L; Yan Y; Liu Z; Abliz Z; Liu G
J Med Chem; 2009 Jul; 52(14):4419-28. PubMed ID: 19530700
[TBL] [Abstract][Full Text] [Related]
33. [Mass spectrometric approach of proteomics].
Yamaguchi K
Tanpakushitsu Kakusan Koso; 2009 Sep; 54(12 Suppl):1568-75. PubMed ID: 21089590
[No Abstract] [Full Text] [Related]
34. Efficiency of hit generation and structural characterization in fragment-based ligand discovery.
Larsson A; Jansson A; Åberg A; Nordlund P
Curr Opin Chem Biol; 2011 Aug; 15(4):482-8. PubMed ID: 21724447
[TBL] [Abstract][Full Text] [Related]
35. Halogen-enriched fragment libraries as chemical probes for harnessing halogen bonding in fragment-based lead discovery.
Zimmermann MO; Lange A; Wilcken R; Cieslik MB; Exner TE; Joerger AC; Koch P; Boeckler FM
Future Med Chem; 2014 Apr; 6(6):617-39. PubMed ID: 24895892
[TBL] [Abstract][Full Text] [Related]
36. Dendrimer space exploration: an assessment of dendrimers/dendritic scaffolding as inhibitors of protein-protein interactions, a potential new area of pharmaceutical development.
Mignani S; El Kazzouli S; Bousmina MM; Majoral JP
Chem Rev; 2014 Jan; 114(2):1327-42. PubMed ID: 24127777
[No Abstract] [Full Text] [Related]
37. Integrating surface plasmon resonance biosensor-based interaction kinetic analyses into the lead discovery and optimization process.
Danielson UH
Future Med Chem; 2009 Nov; 1(8):1399-414. PubMed ID: 21426056
[TBL] [Abstract][Full Text] [Related]
38. Structure-based tailoring of compound libraries for high-throughput screening: discovery of novel EphB4 kinase inhibitors.
Kolb P; Kipouros CB; Huang D; Caflisch A
Proteins; 2008 Oct; 73(1):11-8. PubMed ID: 18384152
[TBL] [Abstract][Full Text] [Related]
39. How well can fragments explore accessed chemical space? A case study from heat shock protein 90.
Roughley SD; Hubbard RE
J Med Chem; 2011 Jun; 54(12):3989-4005. PubMed ID: 21561141
[No Abstract] [Full Text] [Related]
40. Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometry.
Whitehurst CE; Nazef N; Annis DA; Hou Y; Murphy DM; Spacciapoli P; Yao Z; Ziebell MR; Cheng CC; Shipps GW; Felsch JS; Lau D; Nash HM
J Biomol Screen; 2006 Mar; 11(2):194-207. PubMed ID: 16490772
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
