268 related articles for article (PubMed ID: 22230199)
41. Detecting protein-small molecule interactions using fluorous small-molecule microarrays.
Vegas AJ; Koehler AN
Methods Mol Biol; 2010; 669():43-55. PubMed ID: 20857356
[TBL] [Abstract][Full Text] [Related]
42. Computational approach to de novo discovery of fragment binding for novel protein states.
Konteatis ZD; Klon AE; Zou J; Meshkat S
Methods Enzymol; 2011; 493():357-80. PubMed ID: 21371598
[TBL] [Abstract][Full Text] [Related]
43. Artificial synthetic receptors as regulators of protein activity.
Dutt S; Wilch C; Schrader T
Chem Commun (Camb); 2011 May; 47(19):5376-83. PubMed ID: 21394349
[TBL] [Abstract][Full Text] [Related]
44. Small molecule inhibitors of histone acetyltransferases as epigenetic tools and drug candidates.
Furdas SD; Kannan S; Sippl W; Jung M
Arch Pharm (Weinheim); 2012 Jan; 345(1):7-21. PubMed ID: 22234972
[TBL] [Abstract][Full Text] [Related]
45. Hot spot-based design of small-molecule inhibitors for protein-protein interactions.
Guo W; Wisniewski JA; Ji H
Bioorg Med Chem Lett; 2014 Jun; 24(11):2546-54. PubMed ID: 24751445
[TBL] [Abstract][Full Text] [Related]
46. Biophysical methods for identifying fragment-based inhibitors of protein-protein interactions.
Pfaff SJ; Chimenti MS; Kelly MJ; Arkin MR
Methods Mol Biol; 2015; 1278():587-613. PubMed ID: 25859978
[TBL] [Abstract][Full Text] [Related]
47. Bioactivity-guided navigation of chemical space.
Bon RS; Waldmann H
Acc Chem Res; 2010 Aug; 43(8):1103-14. PubMed ID: 20481515
[TBL] [Abstract][Full Text] [Related]
48. Recent trends and observations in the design of high-quality screening collections.
Renner S; Popov M; Schuffenhauer A; Roth HJ; Breitenstein W; Marzinzik A; Lewis I; Krastel P; Nigsch F; Jenkins J; Jacoby E
Future Med Chem; 2011 Apr; 3(6):751-66. PubMed ID: 21554080
[TBL] [Abstract][Full Text] [Related]
49. Advances in surface plasmon resonance biomolecular interaction analysis mass spectrometry (BIA/MS).
Nelson RW; Krone JR
J Mol Recognit; 1999; 12(2):77-93. PubMed ID: 10398399
[TBL] [Abstract][Full Text] [Related]
50. A Structural Perspective on the Modulation of Protein-Protein Interactions with Small Molecules.
Demirel HC; Dogan T; Tuncbag N
Curr Top Med Chem; 2018; 18(8):700-713. PubMed ID: 29852872
[TBL] [Abstract][Full Text] [Related]
51. Experimental and computational active site mapping as a starting point to fragment-based lead discovery.
Behnen J; Köster H; Neudert G; Craan T; Heine A; Klebe G
ChemMedChem; 2012 Feb; 7(2):248-61. PubMed ID: 22213702
[TBL] [Abstract][Full Text] [Related]
52. Diversity-oriented fluorescence library approaches for probe discovery and development.
Vendrell M; Lee JS; Chang YT
Curr Opin Chem Biol; 2010 Jun; 14(3):383-9. PubMed ID: 20227904
[TBL] [Abstract][Full Text] [Related]
53. Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery.
Erlanson DA; Arndt JW; Cancilla MT; Cao K; Elling RA; English N; Friedman J; Hansen SK; Hession C; Joseph I; Kumaravel G; Lee WC; Lind KE; McDowell RS; Miatkowski K; Nguyen C; Nguyen TB; Park S; Pathan N; Penny DM; Romanowski MJ; Scott D; Silvian L; Simmons RL; Tangonan BT; Yang W; Sun L
Bioorg Med Chem Lett; 2011 May; 21(10):3078-83. PubMed ID: 21459573
[TBL] [Abstract][Full Text] [Related]
54. Synergism of virtual screening and medicinal chemistry: identification and optimization of allosteric antagonists of metabotropic glutamate receptor 1.
Noeske T; Trifanova D; Kauss V; Renner S; Parsons CG; Schneider G; Weil T
Bioorg Med Chem; 2009 Aug; 17(15):5708-15. PubMed ID: 19574055
[TBL] [Abstract][Full Text] [Related]
55. SwissParam: a fast force field generation tool for small organic molecules.
Zoete V; Cuendet MA; Grosdidier A; Michielin O
J Comput Chem; 2011 Aug; 32(11):2359-68. PubMed ID: 21541964
[TBL] [Abstract][Full Text] [Related]
56. Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases.
Comess KM; Sun C; Abad-Zapatero C; Goedken ER; Gum RJ; Borhani DW; Argiriadi M; Groebe DR; Jia Y; Clampit JE; Haasch DL; Smith HT; Wang S; Song D; Coen ML; Cloutier TE; Tang H; Cheng X; Quinn C; Liu B; Xin Z; Liu G; Fry EH; Stoll V; Ng TI; Banach D; Marcotte D; Burns DJ; Calderwood DJ; Hajduk PJ
ACS Chem Biol; 2011 Mar; 6(3):234-44. PubMed ID: 21090814
[TBL] [Abstract][Full Text] [Related]
57. Identification of novel inhibitors of tropomyosin-related kinase A through the structure-based virtual screening with homology-modeled protein structure.
Park H; Chi O; Kim J; Hong S
J Chem Inf Model; 2011 Nov; 51(11):2986-93. PubMed ID: 22017333
[TBL] [Abstract][Full Text] [Related]
58. Protein-Observed Fluorine NMR: A Bioorthogonal Approach for Small Molecule Discovery.
Arntson KE; Pomerantz WC
J Med Chem; 2016 Jun; 59(11):5158-71. PubMed ID: 26599421
[TBL] [Abstract][Full Text] [Related]
59. From experimental design to validated hits a comprehensive walk-through of fragment lead identification using surface plasmon resonance.
Giannetti AM
Methods Enzymol; 2011; 493():169-218. PubMed ID: 21371592
[TBL] [Abstract][Full Text] [Related]
60. Docking methods for structure-based library design.
Cavasotto CN; Phatak SS
Methods Mol Biol; 2011; 685():155-74. PubMed ID: 20981523
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
