These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 22230336)

  • 21. Metabolomics-on-a-chip and predictive systems toxicology in microfluidic bioartificial organs.
    Shintu L; Baudoin R; Navratil V; Prot JM; Pontoizeau C; Defernez M; Blaise BJ; Domange C; Péry AR; Toulhoat P; Legallais C; Brochot C; Leclerc E; Dumas ME
    Anal Chem; 2012 Feb; 84(4):1840-8. PubMed ID: 22242722
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hepatotoxicity of acetaminophen and N-acetyl-p-benzoquinone imine and enhancement by fructose.
    Hojo M; Hanioka K; Miyata M; Yamazoe Y
    Xenobiotica; 2000 Sep; 30(9):933-41. PubMed ID: 11055270
    [TBL] [Abstract][Full Text] [Related]  

  • 23. LC-MS analyses of N-acetyl-p-benzoquinone imine-adducts of glutathione, cysteine, N-acetylcysteine, and albumin in a plasma sample: A case study from a patient with a rare acetaminophen-induced acute swelling rash.
    Ozawa M; Kubo T; Lee SH; Oe T
    J Toxicol Sci; 2019; 44(8):559-563. PubMed ID: 31378767
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi.
    Henderson CJ; Wolf CR; Kitteringham N; Powell H; Otto D; Park BK
    Proc Natl Acad Sci U S A; 2000 Nov; 97(23):12741-5. PubMed ID: 11058152
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Isatidis Folium alleviates acetaminophen-induced liver injury in mice by enhancing the endogenous antioxidant system.
    Ding CH; Zhu H
    Environ Toxicol; 2020 Nov; 35(11):1251-1259. PubMed ID: 32677766
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Tanshinone IIA attenuates acetaminophen-induced hepatotoxicity through HOTAIR-Nrf2-MRP2/4 signaling pathway.
    Zhang X; Wang T; Yang Y; Li R; Chen Y; Li R; Jiang X; Wang L
    Biomed Pharmacother; 2020 Oct; 130():110547. PubMed ID: 32777703
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Distinct roles of NF-kappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity.
    Dambach DM; Durham SK; Laskin JD; Laskin DL
    Toxicol Appl Pharmacol; 2006 Mar; 211(2):157-65. PubMed ID: 16081117
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Acetaminophen analog N-acetyl-m-aminophenol, but not its reactive metabolite, N-acetyl-p-benzoquinone imine induces CYP3A activity via inhibition of protein degradation.
    Santoh M; Sanoh S; Ohtsuki Y; Ejiri Y; Kotake Y; Ohta S
    Biochem Biophys Res Commun; 2017 May; 486(3):639-644. PubMed ID: 28341123
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Trapping of NAPQI, the intermediate toxic paracetamol metabolite, by aqueous sulfide (S²⁻) and analysis by GC-MS/MS.
    Trettin A; Batkai S; Thum T; Jordan J; Tsikas D
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Jul; 963():99-105. PubMed ID: 24950097
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Novel approach for evaluating pharmaceuticals toxicity using Daphnia model: analysis of the mode of cytochrome P450-generated metabolite action after acetaminophen exposure.
    Kim RO; Jo MA; Song J; Kim IC; Yoon S; Kim WK
    Aquat Toxicol; 2018 Mar; 196():35-42. PubMed ID: 29328974
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Acetaminophen and NAPQI are toxic to auditory cells via oxidative and endoplasmic reticulum stress-dependent pathways.
    Kalinec GM; Thein P; Parsa A; Yorgason J; Luxford W; Urrutia R; Kalinec F
    Hear Res; 2014 Jul; 313():26-37. PubMed ID: 24793116
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Reduction of toxic metabolite formation of acetaminophen.
    Hazai E; Vereczkey L; Monostory K
    Biochem Biophys Res Commun; 2002 Mar; 291(4):1089-94. PubMed ID: 11866476
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Protective effects of hydrogen sulfide anions against acetaminophen-induced hepatotoxicity in mice.
    Ishii I; Kamata S; Hagiya Y; Abiko Y; Kasahara T; Kumagai Y
    J Toxicol Sci; 2015 Dec; 40(6):837-41. PubMed ID: 26558465
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytes.
    Jetten MJ; Ruiz-Aracama A; Coonen ML; Claessen SM; van Herwijnen MH; Lommen A; van Delft JH; Peijnenburg AA; Kleinjans JC
    Arch Toxicol; 2016 May; 90(5):1103-15. PubMed ID: 26104854
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Increased mitochondrial ROS formation by acetaminophen in human hepatic cells is associated with gene expression changes suggesting disruption of the mitochondrial electron transport chain.
    Jiang J; Briedé JJ; Jennen DG; Van Summeren A; Saritas-Brauers K; Schaart G; Kleinjans JC; de Kok TM
    Toxicol Lett; 2015 Apr; 234(2):139-50. PubMed ID: 25704631
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation.
    Jiang Y; Fan X; Wang Y; Tan H; Chen P; Zeng H; Huang M; Bi H
    Chem Biol Interact; 2015 Apr; 231():83-9. PubMed ID: 25753323
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Targeting mitochondria with methylene blue protects mice against acetaminophen-induced liver injury.
    Lee KK; Imaizumi N; Chamberland SR; Alder NN; Boelsterli UA
    Hepatology; 2015 Jan; 61(1):326-36. PubMed ID: 25142022
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Polyphenols reported to shift APAP-induced changes in MAPK signaling and toxicity outcomes.
    Nguyen NU; Stamper BD
    Chem Biol Interact; 2017 Nov; 277():129-136. PubMed ID: 28918124
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Enolate-Forming Phloretin Pharmacophores: Hepatoprotection in an Experimental Model of Drug-Induced Toxicity.
    Geohagen BC; Vydyanathan A; Kosharskyy B; Shaparin N; Gavin T; LoPachin RM
    J Pharmacol Exp Ther; 2016 Jun; 357(3):476-86. PubMed ID: 27029584
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A monkey model of acetaminophen-induced hepatotoxicity; phenotypic similarity to human.
    Tamai S; Iguchi T; Niino N; Mikamoto K; Sakurai K; Sayama A; Shimoda H; Takasaki W; Mori K
    J Toxicol Sci; 2017; 42(1):73-84. PubMed ID: 28070111
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.