383 related articles for article (PubMed ID: 22230478)
21. RING finger protein 31 promotes p53 degradation in breast cancer cells.
Zhu J; Zhao C; Zhuang T; Jonsson P; Sinha I; Williams C; Strömblad S; Dahlman-Wright K
Oncogene; 2016 Apr; 35(15):1955-64. PubMed ID: 26148235
[TBL] [Abstract][Full Text] [Related]
22. RBP-J-interacting and tubulin-associated protein induces apoptosis and cell cycle arrest in human hepatocellular carcinoma by activating the p53-Fbxw7 pathway.
Wang H; Yang Z; Liu C; Huang S; Wang H; Chen Y; Chen G
Biochem Biophys Res Commun; 2014 Nov; 454(1):71-7. PubMed ID: 25445601
[TBL] [Abstract][Full Text] [Related]
23. RBM38 plays a tumor-suppressor role via stabilizing the p53-mdm2 loop function in hepatocellular carcinoma.
Ye J; Liang R; Bai T; Lin Y; Mai R; Wei M; Ye X; Li L; Wu F
J Exp Clin Cancer Res; 2018 Sep; 37(1):212. PubMed ID: 30176896
[TBL] [Abstract][Full Text] [Related]
24. WP1130 increases doxorubicin sensitivity in hepatocellular carcinoma cells through usp9x-dependent p53 degradation.
Liu H; Chen W; Liang C; Chen BW; Zhi X; Zhang S; Zheng X; Bai X; Liang T
Cancer Lett; 2015 Jun; 361(2):218-25. PubMed ID: 25749422
[TBL] [Abstract][Full Text] [Related]
25. Synthetic Proteins Potently and Selectively Bind the Oncoprotein Gankyrin, Modulate Its Interaction with S6 ATPase, and Suppress Gankyrin/MDM2-Dependent Ubiquitination of p53.
Chapman AM; McNaughton BR
ACS Chem Biol; 2015 Aug; 10(8):1880-6. PubMed ID: 25955581
[TBL] [Abstract][Full Text] [Related]
26. Downregulation of SNAIL sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis by regulating the NF-κB pathway.
Wan Z; Pan H; Liu S; Zhu J; Qi W; Fu K; Zhao T; Liang J
Oncol Rep; 2015 Mar; 33(3):1560-6. PubMed ID: 25607597
[TBL] [Abstract][Full Text] [Related]
27. DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer.
Wu DW; Lee MC; Wang J; Chen CY; Cheng YW; Lee H
Oncogene; 2014 Mar; 33(12):1515-26. PubMed ID: 23584477
[TBL] [Abstract][Full Text] [Related]
28. Gankyrin: a new oncoprotein and regulator of pRb and p53.
Dawson S; Higashitsuji H; Wilkinson AJ; Fujita J; Mayer RJ
Trends Cell Biol; 2006 May; 16(5):229-33. PubMed ID: 16581249
[TBL] [Abstract][Full Text] [Related]
29. ZCCHC10 suppresses lung cancer progression and cisplatin resistance by attenuating MDM2-mediated p53 ubiquitination and degradation.
Ning Y; Hui N; Qing B; Zhuo Y; Sun W; Du Y; Liu S; Liu K; Zhou J
Cell Death Dis; 2019 May; 10(6):414. PubMed ID: 31138778
[TBL] [Abstract][Full Text] [Related]
30. BIRC6 promotes hepatocellular carcinogenesis: interaction of BIRC6 with p53 facilitating p53 degradation.
Tang W; Xue R; Weng S; Wu J; Fang Y; Wang Y; Ji L; Hu T; Liu T; Huang X; Chen S; Shen X; Zhang S; Dong L
Int J Cancer; 2015 Mar; 136(6):E475-87. PubMed ID: 25196217
[TBL] [Abstract][Full Text] [Related]
31. Rock2 regulates Cdc25A through ubiquitin proteasome system in hepatocellular carcinoma cells.
Liu T; Yu X; Li G; Yuan R; Wang Q; Tang P; Wu L; Liu X; Peng X; Shao J
Exp Cell Res; 2012 Oct; 318(16):1994-2003. PubMed ID: 22705122
[TBL] [Abstract][Full Text] [Related]
32. Germline Duplication of SNORA18L5 Increases Risk for HBV-related Hepatocellular Carcinoma by Altering Localization of Ribosomal Proteins and Decreasing Levels of p53.
Cao P; Yang A; Wang R; Xia X; Zhai Y; Li Y; Yang F; Cui Y; Xie W; Liu Y; Liu T; Jia W; Jiang Z; Li Z; Han Y; Gao C; Song Q; Xie B; Zhang L; Zhang H; Zhang J; Shen X; Yuan Y; Yu F; Wang Y; Xu J; Ma Y; Mo Z; Yu W; He F; Zhou G
Gastroenterology; 2018 Aug; 155(2):542-556. PubMed ID: 29702115
[TBL] [Abstract][Full Text] [Related]
33. Inducible liver-specific overexpression of gankyrin in zebrafish results in spontaneous intrahepatic cholangiocarcinoma and hepatocellular carcinoma formation.
Huang SJ; Cheng CL; Chen JR; Gong HY; Liu W; Wu JL
Biochem Biophys Res Commun; 2017 Aug; 490(3):1052-1058. PubMed ID: 28668389
[TBL] [Abstract][Full Text] [Related]
34. Fn14 overcomes cisplatin resistance of high-grade serous ovarian cancer by promoting Mdm2-mediated p53-R248Q ubiquitination and degradation.
Wu AY; Gu LY; Cang W; Cheng MX; Wang WJ; Di W; Huang L; Qiu LH
J Exp Clin Cancer Res; 2019 Apr; 38(1):176. PubMed ID: 31023317
[TBL] [Abstract][Full Text] [Related]
35. Notch2 is a crucial regulator of self-renewal and tumorigenicity in human hepatocellular carcinoma cells.
Wu WR; Zhang R; Shi XD; Yi C; Xu LB; Liu C
Oncol Rep; 2016 Jul; 36(1):181-8. PubMed ID: 27221981
[TBL] [Abstract][Full Text] [Related]
36. Gankyrin drives metabolic reprogramming to promote tumorigenesis, metastasis and drug resistance through activating β-catenin/c-Myc signaling in human hepatocellular carcinoma.
Liu R; Li Y; Tian L; Shi H; Wang J; Liang Y; Sun B; Wang S; Zhou M; Wu L; Nie J; Lin B; Tang S; Zhang Y; Wang G; Zhang C; Han J; Xu B; Liu L; Gong K; Zheng T
Cancer Lett; 2019 Feb; 443():34-46. PubMed ID: 30503555
[TBL] [Abstract][Full Text] [Related]
37. Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation.
Seo SK; Hwang CS; Choe TB; Hong SI; Yi JY; Hwang SG; Lee HG; Oh ST; Lee YH; Park IC
Oncotarget; 2015 Sep; 6(28):26528-40. PubMed ID: 25605253
[TBL] [Abstract][Full Text] [Related]
38. Gankyrin promotes the proliferation of human pancreatic cancer.
Meng Y; He L; Guo X; Tang S; Zhao X; Du R; Jin J; Bi Q; Li H; Nie Y; Liu J; Fan D
Cancer Lett; 2010 Nov; 297(1):9-17. PubMed ID: 20483533
[TBL] [Abstract][Full Text] [Related]
39. Human inhibitor of growth 1 inhibits hepatoma cell growth and influences p53 stability in a variant-dependent manner.
Zhu Z; Luo Z; Li Y; Ni C; Li H; Zhu M
Hepatology; 2009 Feb; 49(2):504-12. PubMed ID: 19085961
[TBL] [Abstract][Full Text] [Related]
40. Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas.
Higashitsuji H; Itoh K; Nagao T; Dawson S; Nonoguchi K; Kido T; Mayer RJ; Arii S; Fujita J
Nat Med; 2000 Jan; 6(1):96-9. PubMed ID: 10613832
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
