These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 22232010)

  • 1. Identification of putative molecular imaging probes for BACE-1 by accounting for protein flexibility in virtual screening.
    Lang H; Huang X; Yang Y
    J Alzheimers Dis; 2012; 29(2):351-9. PubMed ID: 22232010
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alzheimer's disease.
    De-Paula VJ; Radanovic M; Diniz BS; Forlenza OV
    Subcell Biochem; 2012; 65():329-52. PubMed ID: 23225010
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients.
    Li R; Lindholm K; Yang LB; Yue X; Citron M; Yan R; Beach T; Sue L; Sabbagh M; Cai H; Wong P; Price D; Shen Y
    Proc Natl Acad Sci U S A; 2004 Mar; 101(10):3632-7. PubMed ID: 14978286
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development and characterization of a novel membrane assay for full-length BACE-1 at pH 6.0.
    Saric A; Brügge Lz; Müller-Pompalla D; Rysiok T; Ousson S; Permanne B; Quattropani A; Busch M; Beher D; Hussain I
    J Biomol Screen; 2013 Mar; 18(3):277-85. PubMed ID: 23023105
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In Silico Design of Beta-Secretase Inhibitors in Alzheimer's Disease.
    Semighini EP
    Chem Biol Drug Des; 2015 Sep; 86(3):284-90. PubMed ID: 25476252
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Decreased expression of GGA3 protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein.
    Santosa C; Rasche S; Barakat A; Bellingham SA; Ho M; Tan J; Hill AF; Masters CL; McLean C; Evin G
    Neurobiol Dis; 2011 Jul; 43(1):176-83. PubMed ID: 21440067
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comprehensive 3D-QSAR and binding mode of BACE-1 inhibitors using R-group search and molecular docking.
    Huang D; Liu Y; Shi B; Li Y; Wang G; Liang G
    J Mol Graph Model; 2013 Sep; 45():65-83. PubMed ID: 24004830
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Amyloid precursor protein and BACE function as oligomers.
    Multhaup G
    Neurodegener Dis; 2006; 3(4-5):270-4. PubMed ID: 17047367
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation.
    Tanahashi H; Tabira T
    Neurosci Lett; 2007 Nov; 428(2-3):103-8. PubMed ID: 17961921
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design and synthesis of novel 3,5-bis-N-(aryl/heteroaryl) carbamoyl-4-aryl-1,4-dihydropyridines as small molecule BACE-1 inhibitors.
    Razzaghi-Asl N; Firuzi O; Hemmateenejad B; Javidnia K; Edraki N; Miri R
    Bioorg Med Chem; 2013 Nov; 21(22):6893-909. PubMed ID: 24113238
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein-protein interactions in the assembly and subcellular trafficking of the BACE (beta-site amyloid precursor protein-cleaving enzyme) complex of Alzheimer's disease.
    Parsons RB; Austen BM
    Biochem Soc Trans; 2007 Nov; 35(Pt 5):974-9. PubMed ID: 17956258
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting BACE with small inhibitory nucleic acids - a future for Alzheimer's disease therapy?
    Nawrot B
    Acta Biochim Pol; 2004; 51(2):431-44. PubMed ID: 15218540
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MicroRNA-384 regulates both amyloid precursor protein and β-secretase expression and is a potential biomarker for Alzheimer's disease.
    Liu CG; Wang JL; Li L; Wang PC
    Int J Mol Med; 2014 Jul; 34(1):160-6. PubMed ID: 24827165
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A physicochemical descriptor based method for effective and rapid screening of dual inhibitors against BACE-1 and GSK-3β as targets for Alzheimer's disease.
    Kumar A; Srivastava G; Sharma A
    Comput Biol Chem; 2017 Dec; 71():1-9. PubMed ID: 28950235
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein flexibility in virtual screening: the BACE-1 case study.
    Cosconati S; Marinelli L; Di Leva FS; La Pietra V; De Simone A; Mancini F; Andrisano V; Novellino E; Goodsell DS; Olson AJ
    J Chem Inf Model; 2012 Oct; 52(10):2697-704. PubMed ID: 23005250
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Promising multifunctional anti-Alzheimer's dimer bis(7)-Cognitin acting as an activator of protein kinase C regulates activities of alpha-secretase and BACE-1 concurrently.
    Fu H; Dou J; Li W; Cui W; Mak S; Hu Q; Luo J; Lam CS; Pang Y; Youdim MB; Han Y
    Eur J Pharmacol; 2009 Nov; 623(1-3):14-21. PubMed ID: 19765582
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ensemble-docking approach on BACE-1: pharmacophore perception and guidelines for drug design.
    Limongelli V; Marinelli L; Cosconati S; Braun HA; Schmidt B; Novellino E
    ChemMedChem; 2007 May; 2(5):667-78. PubMed ID: 17407105
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BACE: Therapeutic target and potential biomarker for Alzheimer's disease.
    Evin G; Barakat A; Masters CL
    Int J Biochem Cell Biol; 2010 Dec; 42(12):1923-6. PubMed ID: 20817005
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
    Hussain I; Hawkins J; Harrison D; Hille C; Wayne G; Cutler L; Buck T; Walter D; Demont E; Howes C; Naylor A; Jeffrey P; Gonzalez MI; Dingwall C; Michel A; Redshaw S; Davis JB
    J Neurochem; 2007 Feb; 100(3):802-9. PubMed ID: 17156133
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity.
    Tesco G; Koh YH; Kang EL; Cameron AN; Das S; Sena-Esteves M; Hiltunen M; Yang SH; Zhong Z; Shen Y; Simpkins JW; Tanzi RE
    Neuron; 2007 Jun; 54(5):721-37. PubMed ID: 17553422
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.