BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 22232553)

  • 1. Low density lipoprotein (LDL) receptor-related protein 6 (LRP6) regulates body fat and glucose homeostasis by modulating nutrient sensing pathways and mitochondrial energy expenditure.
    Liu W; Singh R; Choi CS; Lee HY; Keramati AR; Samuel VT; Lifton RP; Shulman GI; Mani A
    J Biol Chem; 2012 Mar; 287(10):7213-23. PubMed ID: 22232553
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans.
    Singh R; De Aguiar RB; Naik S; Mani S; Ostadsharif K; Wencker D; Sotoudeh M; Malekzadeh R; Sherwin RS; Mani A
    Cell Metab; 2013 Feb; 17(2):197-209. PubMed ID: 23395167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bradykinin inhibits hepatic gluconeogenesis in obese mice.
    Barros CC; Haro A; Russo FJ; Schadock I; Almeida SS; Reis FC; Moraes MR; Haidar A; Hirata AE; Mori M; Bacurau RF; Würtele M; Bader M; Pesquero JB; Araujo RC
    Lab Invest; 2012 Oct; 92(10):1419-27. PubMed ID: 22868909
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Low-Density Lipoprotein Receptor-Related Protein 6 (LRP6) Is a Novel Nutritional Therapeutic Target for Hyperlipidemia, Non-Alcoholic Fatty Liver Disease, and Atherosclerosis.
    Go GW
    Nutrients; 2015 Jun; 7(6):4453-64. PubMed ID: 26046396
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Endurance exercise training increases APPL1 expression and improves insulin signaling in the hepatic tissue of diet-induced obese mice, independently of weight loss.
    Marinho R; Ropelle ER; Cintra DE; De Souza CT; Da Silva AS; Bertoli FC; Colantonio E; D'Almeida V; Pauli JR
    J Cell Physiol; 2012 Jul; 227(7):2917-26. PubMed ID: 21938726
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IRS2 signaling in LepR-b neurons suppresses FoxO1 to control energy balance independently of leptin action.
    Sadagurski M; Leshan RL; Patterson C; Rozzo A; Kuznetsova A; Skorupski J; Jones JC; Depinho RA; Myers MG; White MF
    Cell Metab; 2012 May; 15(5):703-12. PubMed ID: 22560222
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Forkhead Box P1 (FOXP1) Transcription Factor Regulates Hepatic Glucose Homeostasis.
    Zou Y; Gong N; Cui Y; Wang X; Cui A; Chen Q; Jiao T; Dong X; Yang H; Zhang S; Fang F; Chang Y
    J Biol Chem; 2015 Dec; 290(51):30607-15. PubMed ID: 26504089
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deletion of tumor necrosis factor-alpha receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis.
    Romanatto T; Roman EA; Arruda AP; Denis RG; Solon C; Milanski M; Moraes JC; Bonfleur ML; Degasperi GR; Picardi PK; Hirabara S; Boschero AC; Curi R; Velloso LA
    J Biol Chem; 2009 Dec; 284(52):36213-36222. PubMed ID: 19858212
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Deletion of hepatic FoxO1/3/4 genes in mice significantly impacts on glucose metabolism through downregulation of gluconeogenesis and upregulation of glycolysis.
    Xiong X; Tao R; DePinho RA; Dong XC
    PLoS One; 2013; 8(8):e74340. PubMed ID: 24015318
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism.
    Tang Y; Wallace M; Sanchez-Gurmaches J; Hsiao WY; Li H; Lee PL; Vernia S; Metallo CM; Guertin DA
    Nat Commun; 2016 Apr; 7():11365. PubMed ID: 27098609
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Vascular smooth muscle LRP6 limits arteriosclerotic calcification in diabetic LDLR-/- mice by restraining noncanonical Wnt signals.
    Cheng SL; Ramachandran B; Behrmann A; Shao JS; Mead M; Smith C; Krchma K; Bello Arredondo Y; Kovacs A; Kapoor K; Brill LM; Perera R; Williams BO; Towler DA
    Circ Res; 2015 Jul; 117(2):142-56. PubMed ID: 26034040
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatic insulin resistance in ob/ob mice involves increases in ceramide, aPKC activity, and selective impairment of Akt-dependent FoxO1 phosphorylation.
    Sajan MP; Ivey RA; Lee MC; Farese RV
    J Lipid Res; 2015 Jan; 56(1):70-80. PubMed ID: 25395359
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acute exercise reduces hepatic glucose production through inhibition of the Foxo1/HNF-4alpha pathway in insulin resistant mice.
    De Souza CT; Frederico MJ; da Luz G; Cintra DE; Ropelle ER; Pauli JR; Velloso LA
    J Physiol; 2010 Jun; 588(Pt 12):2239-53. PubMed ID: 20421289
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cdkal1, a type 2 diabetes susceptibility gene, regulates mitochondrial function in adipose tissue.
    Palmer CJ; Bruckner RJ; Paulo JA; Kazak L; Long JZ; Mina AI; Deng Z; LeClair KB; Hall JA; Hong S; Zushin PH; Smith KL; Gygi SP; Hagen S; Cohen DE; Banks AS
    Mol Metab; 2017 Oct; 6(10):1212-1225. PubMed ID: 29031721
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reciprocal Regulation of Hepatic TGF-β1 and Foxo1 Controls Gluconeogenesis and Energy Expenditure.
    Pan Q; Ai W; Chen Y; Kim DM; Shen Z; Yang W; Jiang W; Sun Y; Safe S; Guo S
    Diabetes; 2023 Sep; 72(9):1193-1206. PubMed ID: 37343276
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The constitutive androstane receptor is an anti-obesity nuclear receptor that improves insulin sensitivity.
    Gao J; He J; Zhai Y; Wada T; Xie W
    J Biol Chem; 2009 Sep; 284(38):25984-92. PubMed ID: 19617349
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rottlerin induces Wnt co-receptor LRP6 degradation and suppresses both Wnt/β-catenin and mTORC1 signaling in prostate and breast cancer cells.
    Lu W; Lin C; Li Y
    Cell Signal; 2014 Jun; 26(6):1303-9. PubMed ID: 24607787
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of Sam68 triggers adipose tissue browning.
    Zhou J; Cheng M; Boriboun C; Ardehali MM; Jiang C; Liu Q; Han S; Goukassian DA; Tang YL; Zhao TC; Zhao M; Cai L; Richard S; Kishore R; Qin G
    J Endocrinol; 2015 Jun; 225(3):181-9. PubMed ID: 25934704
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transient receptor potential vanilloid type-1 channel regulates diet-induced obesity, insulin resistance, and leptin resistance.
    Lee E; Jung DY; Kim JH; Patel PR; Hu X; Lee Y; Azuma Y; Wang HF; Tsitsilianos N; Shafiq U; Kwon JY; Lee HJ; Lee KW; Kim JK
    FASEB J; 2015 Aug; 29(8):3182-92. PubMed ID: 25888600
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditure.
    Nakae J; Cao Y; Oki M; Orba Y; Sawa H; Kiyonari H; Iskandar K; Suga K; Lombes M; Hayashi Y
    Diabetes; 2008 Mar; 57(3):563-76. PubMed ID: 18162510
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.