92 related articles for article (PubMed ID: 22233543)
1. New protein farnesyltransferase inhibitors in the 3-arylthiophene 2-carboxylic acid series: diversification of the aryl moiety by solid-phase synthesis.
Lethu S; Bosc D; Mouray E; Grellier P; Dubois J
J Enzyme Inhib Med Chem; 2013 Feb; 28(1):163-71. PubMed ID: 22233543
[TBL] [Abstract][Full Text] [Related]
2. Towards the synthesis of bisubstrate inhibitors of protein farnesyltransferase: Synthesis and biological evaluation of new farnesylpyrophosphate analogues.
Duez S; Coudray L; Mouray E; Grellier P; Dubois J
Bioorg Med Chem; 2010 Jan; 18(2):543-56. PubMed ID: 20036564
[TBL] [Abstract][Full Text] [Related]
3. Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors.
Bosc D; Mouray E; Cojean S; Franco CH; Loiseau PM; Freitas-Junior LH; Moraes CB; Grellier P; Dubois J
Eur J Med Chem; 2016 Feb; 109():173-86. PubMed ID: 26774924
[TBL] [Abstract][Full Text] [Related]
4. Discovery of a new class of protein farnesyltransferase inhibitors in the arylthiophene series.
Lethu S; Ginisty M; Bosc D; Dubois J
J Med Chem; 2009 Oct; 52(20):6205-8. PubMed ID: 19772293
[TBL] [Abstract][Full Text] [Related]
5. Development of benzophenone-based farnesyltransferase inhibitors as novel antimalarials.
Kohring K; Wiesner J; Altenkämper M; Sakowski J; Silber K; Hillebrecht A; Haebel P; Dahse HM; Ortmann R; Jomaa H; Klebe G; Schlitzer M
ChemMedChem; 2008 Aug; 3(8):1217-31. PubMed ID: 18470859
[TBL] [Abstract][Full Text] [Related]
6. Structurally simple farnesyltransferase inhibitors arrest the growth of malaria parasites.
Glenn MP; Chang SY; Hucke O; Verlinde CL; Rivas K; Hornéy C; Yokoyama K; Buckner FS; Pendyala PR; Chakrabarti D; Gelb M; Van Voorhis WC; Sebti SM; Hamilton AD
Angew Chem Int Ed Engl; 2005 Aug; 44(31):4903-6. PubMed ID: 16007716
[No Abstract] [Full Text] [Related]
7. Non-thiol farnesyltransferase inhibitors: N-(4-aminoacylamino-3-benzoylphenyl)-3-[5-(4-nitrophenyl)-2 furyl]acrylic acid amides and their antimalarial activity.
Kettler K; Wiesner J; Silber K; Haebel P; Ortmann R; Sattler I; Dahse HM; Jomaa H; Klebe G; Schlitzer M
Eur J Med Chem; 2005 Jan; 40(1):93-101. PubMed ID: 15642414
[TBL] [Abstract][Full Text] [Related]
8. Synthesis of brequinar analogue inhibitors of malaria parasite dihydroorotate dehydrogenase.
Boa AN; Canavan SP; Hirst PR; Ramsey C; Stead AM; McConkey GA
Bioorg Med Chem; 2005 Mar; 13(6):1945-67. PubMed ID: 15727850
[TBL] [Abstract][Full Text] [Related]
9. Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents.
Ohkanda J; Buckner FS; Lockman JW; Yokoyama K; Carrico D; Eastman R; de Luca-Fradley K; Davies W; Croft SL; Van Voorhis WC; Gelb MH; Sebti SM; Hamilton AD
J Med Chem; 2004 Jan; 47(2):432-45. PubMed ID: 14711313
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of a new series of N-ylides as protein farnesyltransferase inhibitors.
Abuhaie CM; Ghinet A; Farce A; Dubois J; Rigo B; Bîcu E
Bioorg Med Chem Lett; 2013 Nov; 23(21):5887-92. PubMed ID: 24054122
[TBL] [Abstract][Full Text] [Related]
11. Farnesyltransferase inhibitors inhibit the growth of malaria parasites in vitro and in vivo.
Wiesner J; Kettler K; Sakowski J; Ortmann R; Katzin AM; Kimura EA; Silber K; Klebe G; Jomaa H; Schlitzer M
Angew Chem Int Ed Engl; 2004 Jan; 43(2):251-4. PubMed ID: 14695623
[No Abstract] [Full Text] [Related]
12. Isothiazole dioxides: synthesis and inhibition of Trypanosoma brucei protein farnesyltransferase.
Clerici F; Gelmi ML; Yokoyama K; Pocar D; Van Voorhis WC; Buckner FS; Gelb MH
Bioorg Med Chem Lett; 2002 Aug; 12(16):2217-20. PubMed ID: 12127541
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of imidazole-containing analogues of farnesyl pyrophosphate and evaluation of their biological activity on protein farnesyltransferase.
Coudray L; de Figueiredo RM; Duez S; Cortial S; Dubois J
J Enzyme Inhib Med Chem; 2009 Aug; 24(4):972-85. PubMed ID: 19555171
[TBL] [Abstract][Full Text] [Related]
14. Antimalarial activity of methylpiperazinyl-substituted benzophenone-based farnesyltransferase inhibitors.
Kettler K; Wiesner J; Ortmann R; Dahse HM; Jomaa H; Schlitzer M
Pharmazie; 2006 Jan; 61(1):63-5. PubMed ID: 16454209
[No Abstract] [Full Text] [Related]
15. Biphenyl-4-ylcarbamoyl thiophene carboxylic acids as potent DHODH inhibitors.
Leban J; Kralik M; Mies J; Baumgartner R; Gassen M; Tasler S
Bioorg Med Chem Lett; 2006 Jan; 16(2):267-70. PubMed ID: 16246558
[TBL] [Abstract][Full Text] [Related]
16. Solid-phase synthesis and pharmacological evaluation of a library of peptidomimetics as potential farnesyltransferase inhibitors: an approach to new lead compounds.
Gilleron P; Millet R; Houssin R; Wlodarczyk N; Farce A; Lemoine A; Goossens JF; Chavatte P; Pommery N; Hénichart JP
Eur J Med Chem; 2006 Jun; 41(6):745-55. PubMed ID: 16647166
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of a new series of phenothiazine-containing protein farnesyltransferase inhibitors.
Abuhaie CM; Ghinet A; Farce A; Dubois J; Gautret P; Rigo B; Belei D; Bîcu E
Eur J Med Chem; 2013 Jan; 59():101-10. PubMed ID: 23207411
[TBL] [Abstract][Full Text] [Related]
18. Structure-activity relationships of novel anti-malarial agents part 8. Effect of different central aryls in biarylacryloylaminobenzophenones on antimalarial activity.
Wiesner J; Mitsch A; Altenkämper M; Ortmann R; Jomaa H; Schlitzer M
Pharmazie; 2003 Dec; 58(12):854-6. PubMed ID: 14703959
[TBL] [Abstract][Full Text] [Related]
19. Cell permeation of a Trypanosoma brucei aldolase inhibitor: evaluation of different enzyme-labile phosphate protecting groups.
Azéma L; Lherbet C; Baudoin C; Blonski C
Bioorg Med Chem Lett; 2006 Jul; 16(13):3440-3. PubMed ID: 16632348
[TBL] [Abstract][Full Text] [Related]
20. Novel lead structures for antimalarial farnesyltransferase inhibitors.
Kettler K; Sakowski J; Wiesner J; Ortmann R; Jomaa H; Schlitzer M
Pharmazie; 2005 May; 60(5):323-7. PubMed ID: 15918578
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
