150 related articles for article (PubMed ID: 22234485)
1. Sphingosine kinase inhibition exerts both pro- and anti-atherogenic effects in low-density lipoprotein receptor-deficient (LDL-R(-/-)) mice.
Poti F; Bot M; Costa S; Bergonzini V; Maines L; Varga G; Freise H; Robenek H; Simoni M; Nofer JR
Thromb Haemost; 2012 Mar; 107(3):552-61. PubMed ID: 22234485
[TBL] [Abstract][Full Text] [Related]
2. SKI-II--a sphingosine kinase 1 inhibitor--exacerbates atherosclerosis in low-density lipoprotein receptor-deficient (LDL-R-/-) mice on high cholesterol diet.
Potì F; Ceglarek U; Burkhardt R; Simoni M; Nofer JR
Atherosclerosis; 2015 May; 240(1):212-5. PubMed ID: 25801013
[TBL] [Abstract][Full Text] [Related]
3. KRP-203, sphingosine 1-phosphate receptor type 1 agonist, ameliorates atherosclerosis in LDL-R-/- mice.
Potì F; Gualtieri F; Sacchi S; Weißen-Plenz G; Varga G; Brodde M; Weber C; Simoni M; Nofer JR
Arterioscler Thromb Vasc Biol; 2013 Jul; 33(7):1505-12. PubMed ID: 23640484
[TBL] [Abstract][Full Text] [Related]
4. Elevating Endogenous Sphingosine-1-Phosphate (S1P) Levels Improves Endothelial Function and Ameliorates Atherosclerosis in Low Density Lipoprotein Receptor-Deficient (LDL-R-/-) Mice.
Feuerborn R; Besser M; Potì F; Burkhardt R; Weißen-Plenz G; Ceglarek U; Simoni M; Proia RL; Freise H; Nofer JR
Thromb Haemost; 2018 Aug; 118(8):1470-1480. PubMed ID: 30060257
[TBL] [Abstract][Full Text] [Related]
5. FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice.
Nofer JR; Bot M; Brodde M; Taylor PJ; Salm P; Brinkmann V; van Berkel T; Assmann G; Biessen EA
Circulation; 2007 Jan; 115(4):501-8. PubMed ID: 17242282
[TBL] [Abstract][Full Text] [Related]
6. Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R⁻/⁻) mice.
Poti F; Costa S; Bergonzini V; Galletti M; Pignatti E; Weber C; Simoni M; Nofer JR
Vascul Pharmacol; 2012 Aug; 57(1):56-64. PubMed ID: 22459073
[TBL] [Abstract][Full Text] [Related]
7. The Sphingosine Kinase 2 Inhibitor ABC294640 Reduces the Growth of Prostate Cancer Cells and Results in Accumulation of Dihydroceramides In Vitro and In Vivo.
Venant H; Rahmaniyan M; Jones EE; Lu P; Lilly MB; Garrett-Mayer E; Drake RR; Kraveka JM; Smith CD; Voelkel-Johnson C
Mol Cancer Ther; 2015 Dec; 14(12):2744-52. PubMed ID: 26494858
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of sphingosine kinase-2 suppresses inflammation and attenuates graft injury after liver transplantation in rats.
Liu Q; Rehman H; Shi Y; Krishnasamy Y; Lemasters JJ; Smith CD; Zhong Z
PLoS One; 2012; 7(7):e41834. PubMed ID: 22848628
[TBL] [Abstract][Full Text] [Related]
9. Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo.
Xun C; Chen MB; Qi L; Tie-Ning Z; Peng X; Ning L; Zhi-Xiao C; Li-Wei W
J Exp Clin Cancer Res; 2015 Sep; 34(1):94. PubMed ID: 26337959
[TBL] [Abstract][Full Text] [Related]
10. The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen.
Schröder M; Richter C; Juan MH; Maltusch K; Giegold O; Quintini G; Pfeilschifter JM; Huwiler A; Radeke HH
Mol Immunol; 2011 May; 48(9-10):1139-48. PubMed ID: 21435724
[TBL] [Abstract][Full Text] [Related]
11. Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma.
Qin Z; Dai L; Trillo-Tinoco J; Senkal C; Wang W; Reske T; Bonstaff K; Del Valle L; Rodriguez P; Flemington E; Voelkel-Johnson C; Smith CD; Ogretmen B; Parsons C
Mol Cancer Ther; 2014 Jan; 13(1):154-64. PubMed ID: 24140934
[TBL] [Abstract][Full Text] [Related]
12. Antitumor activity of sphingosine kinase 2 inhibitor ABC294640 and sorafenib in hepatocellular carcinoma xenografts.
Beljanski V; Lewis CS; Smith CD
Cancer Biol Ther; 2011 Mar; 11(5):524-34. PubMed ID: 21258214
[TBL] [Abstract][Full Text] [Related]
13. Probucol Protects Against Atherosclerosis Through Lipid-lowering and Suppressing Immune Maturation of CD11c+ Dendritic Cells in STZ-induced Diabetic LDLR-/- Mice.
Zhu H; Jin X; Zhao J; Dong Z; Ma X; Xu F; Huang W; Liu G; Zou Y; Wang K; Hu K; Sun A; Ge J
J Cardiovasc Pharmacol; 2015 Jun; 65(6):620-7. PubMed ID: 25714599
[TBL] [Abstract][Full Text] [Related]
14. Targeting sphingosine kinase 2 by ABC294640 inhibits human skin squamous cell carcinoma cell growth.
Zhou J; Chen J; Yu H
Biochem Biophys Res Commun; 2018 Mar; 497(2):535-542. PubMed ID: 29428730
[TBL] [Abstract][Full Text] [Related]
15. Targeting ovarian cancer and chemoresistance through selective inhibition of sphingosine kinase-2 with ABC294640.
White MD; Chan L; Antoon JW; Beckman BS
Anticancer Res; 2013 Sep; 33(9):3573-9. PubMed ID: 24023282
[TBL] [Abstract][Full Text] [Related]
16. Sphingosine kinase inhibitor suppresses a Th1 polarization via the inhibition of immunostimulatory activity in murine bone marrow-derived dendritic cells.
Jung ID; Lee JS; Kim YJ; Jeong YI; Lee CM; Baumruker T; Billlich A; Banno Y; Lee MG; Ahn SC; Park WS; Han J; Park YM
Int Immunol; 2007 Apr; 19(4):411-26. PubMed ID: 17307797
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of sphingosine kinase-2 in a murine model of lupus nephritis.
Snider AJ; Ruiz P; Obeid LM; Oates JC
PLoS One; 2013; 8(1):e53521. PubMed ID: 23301082
[TBL] [Abstract][Full Text] [Related]
18. Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2.
French KJ; Zhuang Y; Maines LW; Gao P; Wang W; Beljanski V; Upson JJ; Green CL; Keller SN; Smith CD
J Pharmacol Exp Ther; 2010 Apr; 333(1):129-39. PubMed ID: 20061445
[TBL] [Abstract][Full Text] [Related]
19. Sphingosine-1-phosphate receptor 3 promotes recruitment of monocyte/macrophages in inflammation and atherosclerosis.
Keul P; Lucke S; von Wnuck Lipinski K; Bode C; Gräler M; Heusch G; Levkau B
Circ Res; 2011 Feb; 108(3):314-23. PubMed ID: 21164103
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of ceramide glucosylation sensitizes lung cancer cells to ABC294640, a first-in-class small molecule SphK2 inhibitor.
Guan S; Liu YY; Yan T; Zhou J
Biochem Biophys Res Commun; 2016 Aug; 476(4):230-236. PubMed ID: 27221045
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
