157 related articles for article (PubMed ID: 22234618)
1. Rectal absorption of vigabatrin, a substrate of the proton coupled amino acid transporter (PAT1, Slc36a1), in rats.
Holm R; Kall MA; Frølund S; Nielsen AL; Jensen A; Broberg ML; Nielsen CU
Pharm Res; 2012 Apr; 29(4):1134-42. PubMed ID: 22234618
[TBL] [Abstract][Full Text] [Related]
2. Sertraline inhibits the transport of PAT1 substrates in vivo and in vitro.
Nielsen CU; Frølund S; Abdulhadi S; Sari H; Langthaler L; Nøhr MK; Kall MA; Brodin B; Holm R
Br J Pharmacol; 2013 Nov; 170(5):1041-52. PubMed ID: 23962042
[TBL] [Abstract][Full Text] [Related]
3. Function and expression of the proton-coupled amino acid transporter PAT1 along the rat gastrointestinal tract: implications for intestinal absorption of gaboxadol.
Broberg Ml; Holm R; Tønsberg H; Frølund S; Ewon KB; Nielsen Al; Brodin B; Jensen A; Kall MA; Christensen KV; Nielsen CU
Br J Pharmacol; 2012 Oct; 167(3):654-65. PubMed ID: 22577815
[TBL] [Abstract][Full Text] [Related]
4. Is oral absorption of vigabatrin carrier-mediated?
Nøhr MK; Juul RV; Thale ZI; Holm R; Kreilgaard M; Nielsen CU
Eur J Pharm Sci; 2015 Mar; 69():10-8. PubMed ID: 25562534
[TBL] [Abstract][Full Text] [Related]
5. Intestinal drug transport via the proton-coupled amino acid transporter PAT1 (SLC36A1) is inhibited by Gly-X(aa) dipeptides.
Frølund S; Langthaler L; Kall MA; Holm R; Nielsen CU
Mol Pharm; 2012 Sep; 9(9):2761-9. PubMed ID: 22853447
[TBL] [Abstract][Full Text] [Related]
6. Vigabatrin transport across the human intestinal epithelial (Caco-2) brush-border membrane is via the H+ -coupled amino-acid transporter hPAT1.
Abbot EL; Grenade DS; Kennedy DJ; Gatfield KM; Thwaites DT
Br J Pharmacol; 2006 Feb; 147(3):298-306. PubMed ID: 16331283
[TBL] [Abstract][Full Text] [Related]
7. The proton-coupled amino acid transporter, SLC36A1 (hPAT1), transports Gly-Gly, Gly-Sar and other Gly-Gly mimetics.
Frølund S; Holm R; Brodin B; Nielsen CU
Br J Pharmacol; 2010 Oct; 161(3):589-600. PubMed ID: 20880398
[TBL] [Abstract][Full Text] [Related]
8. 5-Hydroxy-L-tryptophan alters gaboxadol pharmacokinetics in rats: involvement of PAT1 and rOat1 in gaboxadol absorption and elimination.
Larsen M; Holm R; Jensen KG; Sveigaard C; Brodin B; Nielsen CU
Eur J Pharm Sci; 2010 Jan; 39(1-3):68-75. PubMed ID: 19900542
[TBL] [Abstract][Full Text] [Related]
9. Intestinal gaboxadol absorption via PAT1 (SLC36A1): modified absorption in vivo following co-administration of L-tryptophan.
Larsen M; Holm R; Jensen KG; Brodin B; Nielsen CU
Br J Pharmacol; 2009 Aug; 157(8):1380-9. PubMed ID: 19594759
[TBL] [Abstract][Full Text] [Related]
10. Inhibitory Effects of 17-α-Ethinyl-Estradiol and 17-β-Estradiol on Transport Via the Intestinal Proton-Coupled Amino Acid Transporter (PAT1) Investigated In Vitro and In Vivo.
Nielsen CU; Pedersen M; Müller S; Kæstel T; Bjerg M; Ulaganathan N; Nielsen S; Carlsen KL; Nøhr MK; Holm R
J Pharm Sci; 2021 Jan; 110(1):354-364. PubMed ID: 32835702
[TBL] [Abstract][Full Text] [Related]
11. Transport of the areca nut alkaloid arecaidine by the human proton-coupled amino acid transporter 1 (hPAT1).
Voigt V; Laug L; Zebisch K; Thondorf I; Markwardt F; Brandsch M
J Pharm Pharmacol; 2013 Apr; 65(4):582-90. PubMed ID: 23488788
[TBL] [Abstract][Full Text] [Related]
12. The absorptive flux of the anti-epileptic drug substance vigabatrin is carrier-mediated across Caco-2 cell monolayers.
Nøhr MK; Hansen SH; Brodin B; Holm R; Nielsen CU
Eur J Pharm Sci; 2014 Jan; 51():1-10. PubMed ID: 24008184
[TBL] [Abstract][Full Text] [Related]
13. Intestinal absorption of the antiepileptic drug substance vigabatrin in Göttingen mini-pigs is unaffected by co-administration of amino acids.
Nøhr MK; Holm R; Thale ZI; Nielsen CU
Int J Pharm; 2014 May; 466(1-2):18-20. PubMed ID: 24607206
[TBL] [Abstract][Full Text] [Related]
14. Delta-aminolevulinic acid is a substrate for the amino acid transporter SLC36A1 (hPAT1).
Frølund S; Marquez OC; Larsen M; Brodin B; Nielsen CU
Br J Pharmacol; 2010 Mar; 159(6):1339-53. PubMed ID: 20128809
[TBL] [Abstract][Full Text] [Related]
15. H+/amino acid transporter 1 (PAT1) is the imino acid carrier: An intestinal nutrient/drug transporter in human and rat.
Anderson CM; Grenade DS; Boll M; Foltz M; Wake KA; Kennedy DJ; Munck LK; Miyauchi S; Taylor PM; Campbell FC; Munck BG; Daniel H; Ganapathy V; Thwaites DT
Gastroenterology; 2004 Nov; 127(5):1410-22. PubMed ID: 15521011
[TBL] [Abstract][Full Text] [Related]
16. Substrate specificity and functional characterisation of the H+/amino acid transporter rat PAT2 (Slc36a2).
Kennedy DJ; Gatfield KM; Winpenny JP; Ganapathy V; Thwaites DT
Br J Pharmacol; 2005 Jan; 144(1):28-41. PubMed ID: 15644866
[TBL] [Abstract][Full Text] [Related]
17. Oral and intravenous pharmacokinetics of taurine in sprague-dawley rats: the influence of dose and the possible involvement of the proton-coupled amino acid transporter, PAT1, in oral taurine absorption.
Nielsen CU; Bjerg M; Ulaganathan N; Holm R
Physiol Rep; 2017 Oct; 5(19):. PubMed ID: 29038364
[TBL] [Abstract][Full Text] [Related]
18. Taurine uptake across the human intestinal brush-border membrane is via two transporters: H+-coupled PAT1 (SLC36A1) and Na+- and Cl(-)-dependent TauT (SLC6A6).
Anderson CM; Howard A; Walters JR; Ganapathy V; Thwaites DT
J Physiol; 2009 Feb; 587(Pt 4):731-44. PubMed ID: 19074966
[TBL] [Abstract][Full Text] [Related]
19. Estradiol inhibits the activity of proton-coupled amino acid transporter PAT1 expressed in Xenopus oocytes.
Shan L; Yang Y; Wang J; Zuo J; Dong X; Li C; Li D
Eur J Pharmacol; 2012 Nov; 695(1-3):34-9. PubMed ID: 22975709
[TBL] [Abstract][Full Text] [Related]
20. The orally active antihyperglycemic drug beta-guanidinopropionic acid is transported by the human proton-coupled amino acid transporter hPAT1.
Metzner L; Dorn M; Markwardt F; Brandsch M
Mol Pharm; 2009; 6(3):1006-11. PubMed ID: 19358571
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]