BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

329 related articles for article (PubMed ID: 22235134)

  • 1. Cellular model of TAR DNA-binding protein 43 (TDP-43) aggregation based on its C-terminal Gln/Asn-rich region.
    Budini M; Buratti E; Stuani C; Guarnaccia C; Romano V; De Conti L; Baralle FE
    J Biol Chem; 2012 Mar; 287(10):7512-25. PubMed ID: 22235134
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
    Wils H; Kleinberger G; Janssens J; Pereson S; Joris G; Cuijt I; Smits V; Ceuterick-de Groote C; Van Broeckhoven C; Kumar-Singh S
    Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3858-63. PubMed ID: 20133711
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.
    Xiao S; Sanelli T; Chiang H; Sun Y; Chakrabartty A; Keith J; Rogaeva E; Zinman L; Robertson J
    Acta Neuropathol; 2015 Jul; 130(1):49-61. PubMed ID: 25788357
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinct TDP-43 inclusion morphologies in frontotemporal lobar degeneration with and without amyotrophic lateral sclerosis.
    Tan RH; Yang Y; Kim WS; Dobson-Stone C; Kwok JB; Kiernan MC; Halliday GM
    Acta Neuropathol Commun; 2017 Oct; 5(1):76. PubMed ID: 29078806
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice.
    Igaz LM; Kwong LK; Lee EB; Chen-Plotkin A; Swanson E; Unger T; Malunda J; Xu Y; Winton MJ; Trojanowski JQ; Lee VM
    J Clin Invest; 2011 Feb; 121(2):726-38. PubMed ID: 21206091
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.
    Collins M; Riascos D; Kovalik T; An J; Krupa K; Krupa K; Hood BL; Conrads TP; Renton AE; Traynor BJ; Bowser R
    Acta Neuropathol; 2012 Nov; 124(5):717-32. PubMed ID: 22993125
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy.
    Arai T; Hasegawa M; Nonoka T; Kametani F; Yamashita M; Hosokawa M; Niizato K; Tsuchiya K; Kobayashi Z; Ikeda K; Yoshida M; Onaya M; Fujishiro H; Akiyama H
    Neuropathology; 2010 Apr; 30(2):170-81. PubMed ID: 20102522
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43).
    Bentmann E; Neumann M; Tahirovic S; Rodde R; Dormann D; Haass C
    J Biol Chem; 2012 Jun; 287(27):23079-94. PubMed ID: 22563080
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.
    Khosravi B; Hartmann H; May S; Möhl C; Ederle H; Michaelsen M; Schludi MH; Dormann D; Edbauer D
    Hum Mol Genet; 2017 Feb; 26(4):790-800. PubMed ID: 28040728
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
    Baloh RH
    FEBS J; 2011 Oct; 278(19):3539-49. PubMed ID: 21777387
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells.
    Nonaka T; Arai T; Buratti E; Baralle FE; Akiyama H; Hasegawa M
    FEBS Lett; 2009 Jan; 583(2):394-400. PubMed ID: 19111550
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aggregation of the 35-kDa fragment of TDP-43 causes formation of cytoplasmic inclusions and alteration of RNA processing.
    Che MX; Jiang YJ; Xie YY; Jiang LL; Hu HY
    FASEB J; 2011 Jul; 25(7):2344-53. PubMed ID: 21450909
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of TDP-43 in the pathogenesis of ALS and FTLD.
    Baralle M; Buratti E; Baralle FE
    Biochem Soc Trans; 2013 Dec; 41(6):1536-40. PubMed ID: 24256250
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aggresome formation and liquid-liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 43.
    Watanabe S; Inami H; Oiwa K; Murata Y; Sakai S; Komine O; Sobue A; Iguchi Y; Katsuno M; Yamanaka K
    Cell Death Dis; 2020 Oct; 11(10):909. PubMed ID: 33097688
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments.
    Swarup V; Phaneuf D; Bareil C; Robertson J; Rouleau GA; Kriz J; Julien JP
    Brain; 2011 Sep; 134(Pt 9):2610-26. PubMed ID: 21752789
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A 43-kDa TDP-43 species is present in aggregates associated with frontotemporal lobar degeneration.
    Bosque PJ; Boyer PJ; Mishra P
    PLoS One; 2013; 8(5):e62301. PubMed ID: 23704877
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Frontotemporal lobar degeneration with TDP-43-positive inclusions and amyotrophic lateral sclerosis with dementia].
    Kishimoto Y; Yokota O; Takeda N; Ikeda C; Arai T
    Nihon Rinsho; 2011 Dec; 69 Suppl 10 Pt 2():384-8. PubMed ID: 22755219
    [No Abstract]   [Full Text] [Related]  

  • 18. Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Igaz LM; Kwong LK; Xu Y; Truax AC; Uryu K; Neumann M; Clark CM; Elman LB; Miller BL; Grossman M; McCluskey LF; Trojanowski JQ; Lee VM
    Am J Pathol; 2008 Jul; 173(1):182-94. PubMed ID: 18535185
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Possible concurrence of TDP-43, tau and other proteins in amyotrophic lateral sclerosis/frontotemporal lobar degeneration.
    Takeda T
    Neuropathology; 2018 Feb; 38(1):72-81. PubMed ID: 28960544
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TDP-43 loss of cellular function through aggregation requires additional structural determinants beyond its C-terminal Q/N prion-like domain.
    Budini M; Romano V; Quadri Z; Buratti E; Baralle FE
    Hum Mol Genet; 2015 Jan; 24(1):9-20. PubMed ID: 25122661
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.