These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

834 related articles for article (PubMed ID: 22236875)

  • 21. The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism.
    Pavlides S; Tsirigos A; Migneco G; Whitaker-Menezes D; Chiavarina B; Flomenberg N; Frank PG; Casimiro MC; Wang C; Pestell RG; Martinez-Outschoorn UE; Howell A; Sotgia F; Lisanti MP
    Cell Cycle; 2010 Sep; 9(17):3485-505. PubMed ID: 20861672
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production.
    Capparelli C; Guido C; Whitaker-Menezes D; Bonuccelli G; Balliet R; Pestell TG; Goldberg AF; Pestell RG; Howell A; Sneddon S; Birbe R; Tsirigos A; Martinez-Outschoorn U; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Jun; 11(12):2285-302. PubMed ID: 22684298
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the "reverse Warburg effect": a transcriptional informatics analysis with validation.
    Pavlides S; Tsirigos A; Vera I; Flomenberg N; Frank PG; Casimiro MC; Wang C; Fortina P; Addya S; Pestell RG; Martinez-Outschoorn UE; Sotgia F; Lisanti MP
    Cell Cycle; 2010 Jun; 9(11):2201-19. PubMed ID: 20519932
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment.
    Salem AF; Al-Zoubi MS; Whitaker-Menezes D; Martinez-Outschoorn UE; Lamb R; Hulit J; Howell A; Gandara R; Sartini M; Galbiati F; Bevilacqua G; Sotgia F; Lisanti MP
    Cell Cycle; 2013 Mar; 12(5):818-25. PubMed ID: 23388463
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Ketone body utilization drives tumor growth and metastasis.
    Martinez-Outschoorn UE; Lin Z; Whitaker-Menezes D; Howell A; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Nov; 11(21):3964-71. PubMed ID: 23082722
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Downregulation of stromal BRCA1 drives breast cancer tumor growth via upregulation of HIF-1α, autophagy and ketone body production.
    Salem AF; Howell A; Sartini M; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Nov; 11(22):4167-73. PubMed ID: 23047605
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis.
    Zhang H; Wang D; Li M; Plecitá-Hlavatá L; D'Alessandro A; Tauber J; Riddle S; Kumar S; Flockton A; McKeon BA; Frid MG; Reisz JA; Caruso P; El Kasmi KC; Ježek P; Morrell NW; Hu CJ; Stenmark KR
    Circulation; 2017 Dec; 136(25):2468-2485. PubMed ID: 28972001
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Positive feedback in Cav-1-ROS signalling in PSCs mediates metabolic coupling between PSCs and tumour cells.
    Shao S; Qin T; Qian W; Yue Y; Xiao Y; Li X; Zhang D; Wang Z; Ma Q; Lei J
    J Cell Mol Med; 2020 Aug; 24(16):9397-9408. PubMed ID: 32633891
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Metabolic reprogramming and two-compartment tumor metabolism: opposing role(s) of HIF1α and HIF2α in tumor-associated fibroblasts and human breast cancer cells.
    Chiavarina B; Martinez-Outschoorn UE; Whitaker-Menezes D; Howell A; Tanowitz HB; Pestell RG; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Sep; 11(17):3280-9. PubMed ID: 22894905
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Pyruvate kinase M knockdown-induced signaling via AMP-activated protein kinase promotes mitochondrial biogenesis, autophagy, and cancer cell survival.
    Prakasam G; Singh RK; Iqbal MA; Saini SK; Tiku AB; Bamezai RNK
    J Biol Chem; 2017 Sep; 292(37):15561-15576. PubMed ID: 28778925
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue.
    Whitaker-Menezes D; Martinez-Outschoorn UE; Flomenberg N; Birbe RC; Witkiewicz AK; Howell A; Pavlides S; Tsirigos A; Ertel A; Pestell RG; Broda P; Minetti C; Lisanti MP; Sotgia F
    Cell Cycle; 2011 Dec; 10(23):4047-64. PubMed ID: 22134189
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment.
    Sotgia F; Martinez-Outschoorn UE; Pavlides S; Howell A; Pestell RG; Lisanti MP
    Breast Cancer Res; 2011 Jul; 13(4):213. PubMed ID: 21867571
    [TBL] [Abstract][Full Text] [Related]  

  • 33. BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies.
    Martinez-Outschoorn UE; Balliet R; Lin Z; Whitaker-Menezes D; Birbe RC; Bombonati A; Pavlides S; Lamb R; Sneddon S; Howell A; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Dec; 11(23):4402-13. PubMed ID: 23172369
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Tumoral microvesicle-activated glycometabolic reprogramming in fibroblasts promotes the progression of oral squamous cell carcinoma.
    Jiang E; Xu Z; Wang M; Yan T; Huang C; Zhou X; Liu Q; Wang L; Chen Y; Wang H; Liu K; Shao Z; Shang Z
    FASEB J; 2019 Apr; 33(4):5690-5703. PubMed ID: 30698991
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Two-compartment tumor metabolism: autophagy in the tumor microenvironment and oxidative mitochondrial metabolism (OXPHOS) in cancer cells.
    Salem AF; Whitaker-Menezes D; Lin Z; Martinez-Outschoorn UE; Tanowitz HB; Al-Zoubi MS; Howell A; Pestell RG; Sotgia F; Lisanti MP
    Cell Cycle; 2012 Jul; 11(13):2545-56. PubMed ID: 22722266
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Oleanolic acid suppresses aerobic glycolysis in cancer cells by switching pyruvate kinase type M isoforms.
    Liu J; Wu N; Ma L; Liu M; Liu G; Zhang Y; Lin X
    PLoS One; 2014; 9(3):e91606. PubMed ID: 24626155
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Glucose Catabolism in Liver Tumors Induced by c-MYC Can Be Sustained by Various PKM1/PKM2 Ratios and Pyruvate Kinase Activities.
    Méndez-Lucas A; Li X; Hu J; Che L; Song X; Jia J; Wang J; Xie C; Driscoll PC; Tschaharganeh DF; Calvisi DF; Yuneva M; Chen X
    Cancer Res; 2017 Aug; 77(16):4355-4364. PubMed ID: 28630053
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts.
    Whitaker-Menezes D; Martinez-Outschoorn UE; Lin Z; Ertel A; Flomenberg N; Witkiewicz AK; Birbe RC; Howell A; Pavlides S; Gandara R; Pestell RG; Sotgia F; Philp NJ; Lisanti MP
    Cell Cycle; 2011 Jun; 10(11):1772-83. PubMed ID: 21558814
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Tumor stroma interaction is mediated by monocarboxylate metabolism.
    Patel BB; Ackerstaff E; Serganova IS; Kerrigan JE; Blasberg RG; Koutcher JA; Banerjee D
    Exp Cell Res; 2017 Mar; 352(1):20-33. PubMed ID: 28132882
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mitochondrial metabolism in cancer metastasis: visualizing tumor cell mitochondria and the "reverse Warburg effect" in positive lymph node tissue.
    Sotgia F; Whitaker-Menezes D; Martinez-Outschoorn UE; Flomenberg N; Birbe RC; Witkiewicz AK; Howell A; Philp NJ; Pestell RG; Lisanti MP
    Cell Cycle; 2012 Apr; 11(7):1445-54. PubMed ID: 22395432
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 42.