230 related articles for article (PubMed ID: 22237496)
1. Direct MRI-guided stereotaxic viral mediated gene transfer of alpha-synuclein in the Göttingen minipig CNS.
Glud AN; Hedegaard C; Nielsen MS; Søorensen JC; Bendixen C; Jensen PH; Mogensen PH; Larsen K; Bjarkam CR
Acta Neurobiol Exp (Wars); 2011; 71(4):508-18. PubMed ID: 22237496
[TBL] [Abstract][Full Text] [Related]
2. Direct gene transfer in the Gottingen minipig CNS using stereotaxic lentiviral microinjections.
Norgaard Glud A; Hedegaard C; Nielsen MS; Sørensen JC; Bendixen C; Jensen PH; Larsen K; Bjarkam CR
Acta Neurobiol Exp (Wars); 2010; 70(3):308-15. PubMed ID: 20871651
[TBL] [Abstract][Full Text] [Related]
3. AAV1/2-induced overexpression of A53T-α-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease.
Ip CW; Klaus LC; Karikari AA; Visanji NP; Brotchie JM; Lang AE; Volkmann J; Koprich JB
Acta Neuropathol Commun; 2017 Feb; 5(1):11. PubMed ID: 28143577
[TBL] [Abstract][Full Text] [Related]
4. rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration.
Oliveras-Salvá M; Van der Perren A; Casadei N; Stroobants S; Nuber S; D'Hooge R; Van den Haute C; Baekelandt V
Mol Neurodegener; 2013 Nov; 8():44. PubMed ID: 24267638
[TBL] [Abstract][Full Text] [Related]
5. Pirouetting pigs: A large non-primate animal model based on unilateral 6-hydroxydopamine lesioning of the nigrostriatal pathway.
Christensen AB; Sørensen JCH; Ettrup KS; Orlowski D; Bjarkam CR
Brain Res Bull; 2018 May; 139():167-173. PubMed ID: 29462643
[TBL] [Abstract][Full Text] [Related]
6. Melatonin prevents dopaminergic cell loss induced by lentiviral vectors expressing A30P mutant alpha-synuclein.
Brito-Armas JM; Baekelandt V; Castro-Hernández JR; González-Hernández T; Rodríguez M; Castro R
Histol Histopathol; 2013 Aug; 28(8):999-1006. PubMed ID: 23444197
[TBL] [Abstract][Full Text] [Related]
7. CRISPR/Cas9-Mediated Generation of Guangxi Bama Minipigs Harboring Three Mutations in α-Synuclein Causing Parkinson's Disease.
Zhu XX; Zhong YZ; Ge YW; Lu KH; Lu SS
Sci Rep; 2018 Aug; 8(1):12420. PubMed ID: 30127453
[TBL] [Abstract][Full Text] [Related]
8. In vivo quantification of glial activation in minipigs overexpressing human α-synuclein.
Lillethorup TP; Glud AN; Landeck N; Alstrup AKO; Jakobsen S; Vang K; Doudet DJ; Brooks DJ; Kirik D; Hinz R; Sørensen JC; Landau AM
Synapse; 2018 Dec; 72(12):e22060. PubMed ID: 30009467
[TBL] [Abstract][Full Text] [Related]
9. Alpha-synuclein expression in the substantia nigra of MPTP-lesioned non-human primates.
Purisai MG; McCormack AL; Langston WJ; Johnston LC; Di Monte DA
Neurobiol Dis; 2005 Dec; 20(3):898-906. PubMed ID: 16006134
[TBL] [Abstract][Full Text] [Related]
10. Dopaminergic neuron loss and up-regulation of chaperone protein mRNA induced by targeted over-expression of alpha-synuclein in mouse substantia nigra.
St Martin JL; Klucken J; Outeiro TF; Nguyen P; Keller-McGandy C; Cantuti-Castelvetri I; Grammatopoulos TN; Standaert DG; Hyman BT; McLean PJ
J Neurochem; 2007 Mar; 100(6):1449-57. PubMed ID: 17241127
[TBL] [Abstract][Full Text] [Related]
11. Direct detection of alpha synuclein oligomers in vivo.
Dimant H; Kalia SK; Kalia LV; Zhu LN; Kibuuka L; Ebrahimi-Fakhari D; McFarland NR; Fan Z; Hyman BT; McLean PJ
Acta Neuropathol Commun; 2013 May; 1():6. PubMed ID: 24252244
[TBL] [Abstract][Full Text] [Related]
12. Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism.
Gleave JA; Arathoon LR; Trinh D; Lizal KE; Giguère N; Barber JHM; Najarali Z; Khan MH; Thiele SL; Semmen MS; Koprich JB; Brotchie JM; Eubanks JH; Trudeau LE; Nash JE
Neurobiol Dis; 2017 Oct; 106():133-146. PubMed ID: 28673739
[TBL] [Abstract][Full Text] [Related]
13. Comparison between α-synuclein wild-type and A53T mutation in a progressive Parkinson's disease model.
Lu J; Sun F; Ma H; Qing H; Deng Y
Biochem Biophys Res Commun; 2015 Sep; 464(4):988-993. PubMed ID: 26192120
[TBL] [Abstract][Full Text] [Related]
14. Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: a new primate model of Parkinson's disease.
Kirik D; Annett LE; Burger C; Muzyczka N; Mandel RJ; Björklund A
Proc Natl Acad Sci U S A; 2003 Mar; 100(5):2884-9. PubMed ID: 12601150
[TBL] [Abstract][Full Text] [Related]
15. Development of an Alpha-synuclein Based Rat Model for Parkinson's Disease via Stereotactic Injection of a Recombinant Adeno-associated Viral Vector.
Van der Perren A; Casteels C; Van Laere K; Gijsbers R; Van den Haute C; Baekelandt V
J Vis Exp; 2016 Feb; (108):53670. PubMed ID: 26967677
[TBL] [Abstract][Full Text] [Related]
16. Heat shock protein 70 reduces α-synuclein-induced predegenerative neuronal dystrophy in the α-synuclein viral gene transfer rat model of Parkinson's disease.
Moloney TC; Hyland R; O'Toole D; Paucard A; Kirik D; O'Doherty A; Gorman AM; Dowd E
CNS Neurosci Ther; 2014 Jan; 20(1):50-8. PubMed ID: 24279716
[TBL] [Abstract][Full Text] [Related]
17. Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.
Kirik D; Rosenblad C; Burger C; Lundberg C; Johansen TE; Muzyczka N; Mandel RJ; Björklund A
J Neurosci; 2002 Apr; 22(7):2780-91. PubMed ID: 11923443
[TBL] [Abstract][Full Text] [Related]
18. Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.
Bourdenx M; Dovero S; Engeln M; Bido S; Bastide MF; Dutheil N; Vollenweider I; Baud L; Piron C; Grouthier V; Boraud T; Porras G; Li Q; Baekelandt V; Scheller D; Michel A; Fernagut PO; Georges F; Courtine G; Bezard E; Dehay B
Acta Neuropathol Commun; 2015 Jul; 3():46. PubMed ID: 26205255
[TBL] [Abstract][Full Text] [Related]
19. Targeting alpha-synuclein with a microRNA-embedded silencing vector in the rat substantia nigra: positive and negative effects.
Khodr CE; Becerra A; Han Y; Bohn MC
Brain Res; 2014 Mar; 1550():47-60. PubMed ID: 24463035
[TBL] [Abstract][Full Text] [Related]
20. Nigral overexpression of alpha-synuclein in the absence of parkin enhances alpha-synuclein phosphorylation but does not modulate dopaminergic neurodegeneration.
Van Rompuy AS; Oliveras-Salvá M; Van der Perren A; Corti O; Van den Haute C; Baekelandt V
Mol Neurodegener; 2015 Jun; 10():23. PubMed ID: 26099628
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
