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5. Identification of residues that underpin interactions within the eukaryotic initiation factor (eIF2) 2B complex. Wang X; Wortham NC; Liu R; Proud CG J Biol Chem; 2012 Mar; 287(11):8263-74. PubMed ID: 22238342 [TBL] [Abstract][Full Text] [Related]
6. Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation. Gomez E; Mohammad SS; Pavitt GD EMBO J; 2002 Oct; 21(19):5292-301. PubMed ID: 12356745 [TBL] [Abstract][Full Text] [Related]
7. PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha. Dey M; Trieselmann B; Locke EG; Lu J; Cao C; Dar AC; Krishnamoorthy T; Dong J; Sicheri F; Dever TE Mol Cell Biol; 2005 Apr; 25(8):3063-75. PubMed ID: 15798194 [TBL] [Abstract][Full Text] [Related]
8. eIF2B is a decameric guanine nucleotide exchange factor with a γ2ε2 tetrameric core. Gordiyenko Y; Schmidt C; Jennings MD; Matak-Vinkovic D; Pavitt GD; Robinson CV Nat Commun; 2014 May; 5():3902. PubMed ID: 24852487 [TBL] [Abstract][Full Text] [Related]
9. Tight binding of the phosphorylated alpha subunit of initiation factor 2 (eIF2alpha) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition of translation initiation. Krishnamoorthy T; Pavitt GD; Zhang F; Dever TE; Hinnebusch AG Mol Cell Biol; 2001 Aug; 21(15):5018-30. PubMed ID: 11438658 [TBL] [Abstract][Full Text] [Related]
10. A yeast purification system for human translation initiation factors eIF2 and eIF2Bε and their use in the diagnosis of CACH/VWM disease. de Almeida RA; Fogli A; Gaillard M; Scheper GC; Boesflug-Tanguy O; Pavitt GD PLoS One; 2013; 8(1):e53958. PubMed ID: 23335982 [TBL] [Abstract][Full Text] [Related]
11. eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine-nucleotide exchange. Pavitt GD; Ramaiah KV; Kimball SR; Hinnebusch AG Genes Dev; 1998 Feb; 12(4):514-26. PubMed ID: 9472020 [TBL] [Abstract][Full Text] [Related]
12. Clues to the mechanism of action of eIF2B, the guanine-nucleotide-exchange factor for translation initiation. Mohammad-Qureshi SS; Jennings MD; Pavitt GD Biochem Soc Trans; 2008 Aug; 36(Pt 4):658-64. PubMed ID: 18631136 [TBL] [Abstract][Full Text] [Related]
13. Critical contacts between the eukaryotic initiation factor 2B (eIF2B) catalytic domain and both eIF2beta and -2gamma mediate guanine nucleotide exchange. Mohammad-Qureshi SS; Haddad R; Hemingway EJ; Richardson JP; Pavitt GD Mol Cell Biol; 2007 Jul; 27(14):5225-34. PubMed ID: 17526738 [TBL] [Abstract][Full Text] [Related]
14. Crystal structure of eukaryotic translation initiation factor 2B. Kashiwagi K; Takahashi M; Nishimoto M; Hiyama TB; Higo T; Umehara T; Sakamoto K; Ito T; Yokoyama S Nature; 2016 Mar; 531(7592):122-5. PubMed ID: 26901872 [TBL] [Abstract][Full Text] [Related]
15. Identification of domains within the epsilon-subunit of the translation initiation factor eIF2B that are necessary for guanine nucleotide exchange activity and eIF2B holoprotein formation. Anthony TG; Fabian JR; Kimball SR; Jefferson LS Biochim Biophys Acta; 2000 Jun; 1492(1):56-62. PubMed ID: 10858531 [TBL] [Abstract][Full Text] [Related]
16. Identification of a regulatory subcomplex in the guanine nucleotide exchange factor eIF2B that mediates inhibition by phosphorylated eIF2. Yang W; Hinnebusch AG Mol Cell Biol; 1996 Nov; 16(11):6603-16. PubMed ID: 8887689 [TBL] [Abstract][Full Text] [Related]
17. A new function and complexity for protein translation initiation factor eIF2B. Jennings MD; Pavitt GD Cell Cycle; 2014; 13(17):2660-5. PubMed ID: 25486352 [TBL] [Abstract][Full Text] [Related]
18. Fusel alcohols regulate translation initiation by inhibiting eIF2B to reduce ternary complex in a mechanism that may involve altering the integrity and dynamics of the eIF2B body. Taylor EJ; Campbell SG; Griffiths CD; Reid PJ; Slaven JW; Harrison RJ; Sims PF; Pavitt GD; Delneri D; Ashe MP Mol Biol Cell; 2010 Jul; 21(13):2202-16. PubMed ID: 20444979 [TBL] [Abstract][Full Text] [Related]
19. Crystal structure of eIF2B and insights into eIF2-eIF2B interactions. Kashiwagi K; Ito T; Yokoyama S FEBS J; 2017 Mar; 284(6):868-874. PubMed ID: 27627185 [TBL] [Abstract][Full Text] [Related]
20. Biochemical analysis of the eIF2beta gamma complex reveals a structural function for eIF2alpha in catalyzed nucleotide exchange. Nika J; Rippel S; Hannig EM J Biol Chem; 2001 Jan; 276(2):1051-6. PubMed ID: 11042214 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]