BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

263 related articles for article (PubMed ID: 22239621)

  • 1. Structural basis for matrix metalloproteinase 1-catalyzed collagenolysis.
    Bertini I; Fragai M; Luchinat C; Melikian M; Toccafondi M; Lauer JL; Fields GB
    J Am Chem Soc; 2012 Feb; 134(4):2100-10. PubMed ID: 22239621
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Collagenolytic Matrix Metalloproteinase Structure-Function Relationships: Insights From Molecular Dynamics Studies.
    Karabencheva-Christova TG; Christov CZ; Fields GB
    Adv Protein Chem Struct Biol; 2017; 109():1-24. PubMed ID: 28683915
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conformational Dynamics of Matrix Metalloproteinase-1·Triple-Helical Peptide Complexes.
    Karabencheva-Christova TG; Christov CZ; Fields GB
    J Phys Chem B; 2018 May; 122(21):5316-5326. PubMed ID: 29161042
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Examination of matrix metalloproteinase-1 in solution: a preference for the pre-collagenolysis state.
    Cerofolini L; Fields GB; Fragai M; Geraldes CFGC; Luchinat C; Parigi G; Ravera E; Svergun DI; Teixeira JMC
    J Biol Chem; 2013 Oct; 288(42):30659-30671. PubMed ID: 24025334
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biophysical studies of matrix metalloproteinase/triple-helix complexes.
    Fields GB
    Adv Protein Chem Struct Biol; 2014; 97():37-48. PubMed ID: 25458354
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1.
    Manka SW; Carafoli F; Visse R; Bihan D; Raynal N; Farndale RW; Murphy G; Enghild JJ; Hohenester E; Nagase H
    Proc Natl Acad Sci U S A; 2012 Jul; 109(31):12461-6. PubMed ID: 22761315
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The interface between catalytic and hemopexin domains in matrix metalloproteinase-1 conceals a collagen binding exosite.
    Arnold LH; Butt LE; Prior SH; Read CM; Fields GB; Pickford AR
    J Biol Chem; 2011 Dec; 286(52):45073-82. PubMed ID: 22030392
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of specific hemopexin-like domain residues that facilitate matrix metalloproteinase collagenolytic activity.
    Lauer-Fields JL; Chalmers MJ; Busby SA; Minond D; Griffin PR; Fields GB
    J Biol Chem; 2009 Sep; 284(36):24017-24. PubMed ID: 19574232
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of Mutations on Structure-Function Relationships of Matrix Metalloproteinase-1.
    Singh W; Fields GB; Christov CZ; Karabencheva-Christova TG
    Int J Mol Sci; 2016 Oct; 17(10):. PubMed ID: 27754420
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transient collagen triple helix binding to a key metalloproteinase in invasion and development.
    Zhao Y; Marcink TC; Sanganna Gari RR; Marsh BP; King GM; Stawikowska R; Fields GB; Van Doren SR
    Structure; 2015 Feb; 23(2):257-69. PubMed ID: 25651059
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of an Electrostatic Ruler Motif for Sequence-Specific Binding of Collagenase to Collagen.
    Subramanian SR; Singam ER; Berinski M; Subramanian V; Wade RC
    J Phys Chem B; 2016 Aug; 120(33):8580-9. PubMed ID: 27245212
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Collagenolytic Matrix Metalloproteinase Activities toward Peptomeric Triple-Helical Substrates.
    Stawikowski MJ; Stawikowska R; Fields GB
    Biochemistry; 2015 May; 54(19):3110-21. PubMed ID: 25897652
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural studies of the MMP-3 interaction with triple-helical collagen introduce new roles for the enzyme in tissue remodelling.
    Manka SW; Bihan D; Farndale RW
    Sci Rep; 2019 Dec; 9(1):18785. PubMed ID: 31827179
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Collagenase unwinds triple-helical collagen prior to peptide bond hydrolysis.
    Chung L; Dinakarpandian D; Yoshida N; Lauer-Fields JL; Fields GB; Visse R; Nagase H
    EMBO J; 2004 Aug; 23(15):3020-30. PubMed ID: 15257288
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Collagen fibril architecture, domain organization, and triple-helical conformation govern its proteolysis.
    Perumal S; Antipova O; Orgel JP
    Proc Natl Acad Sci U S A; 2008 Feb; 105(8):2824-9. PubMed ID: 18287018
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity.
    Chung L; Shimokawa K; Dinakarpandian D; Grams F; Fields GB; Nagase H
    J Biol Chem; 2000 Sep; 275(38):29610-7. PubMed ID: 10871619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The roles of substrate thermal stability and P2 and P1' subsite identity on matrix metalloproteinase triple-helical peptidase activity and collagen specificity.
    Minond D; Lauer-Fields JL; Cudic M; Overall CM; Pei D; Brew K; Visse R; Nagase H; Fields GB
    J Biol Chem; 2006 Dec; 281(50):38302-13. PubMed ID: 17065155
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Matrix metalloproteinase-1 takes advantage of the induced fit mechanism to cleave the triple-helical type I collagen molecule.
    O'Farrell TJ; Guo R; Hasegawa H; Pourmotabbed T
    Biochemistry; 2006 Dec; 45(51):15411-8. PubMed ID: 17176063
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Matrix metalloproteinases and collagen catabolism.
    Lauer-Fields JL; Juska D; Fields GB
    Biopolymers; 2002; 66(1):19-32. PubMed ID: 12228918
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Importance of the Linker Region in Matrix Metalloproteinase-1 Domain Interactions.
    Singh W; Fields GB; Christov CZ; Karabencheva-Christova TG
    RSC Adv; 2016 Jan; 6(28):23223-23232. PubMed ID: 26998255
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.