These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

415 related articles for article (PubMed ID: 22241473)

  • 1. Suppression of hepatocyte proliferation by hepatocyte nuclear factor 4α in adult mice.
    Bonzo JA; Ferry CH; Matsubara T; Kim JH; Gonzalez FJ
    J Biol Chem; 2012 Mar; 287(10):7345-56. PubMed ID: 22241473
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The concomitant loss of APC and HNF4α in adult hepatocytes does not contribute to hepatocarcinogenesis driven by β-catenin activation.
    Sartor C; Bachelot L; Godard C; Lager F; Renault G; Gonzalez FJ; Perret C; Gougelet A; Colnot S
    Liver Int; 2019 Apr; 39(4):727-739. PubMed ID: 30721564
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A negative reciprocal regulatory axis between cyclin D1 and HNF4α modulates cell cycle progression and metabolism in the liver.
    Wu H; Reizel T; Wang YJ; Lapiro JL; Kren BT; Schug J; Rao S; Morgan A; Herman A; Shekels LL; Rassette MS; Lane AN; Cassel T; Fan TWM; Manivel JC; Gunewardena S; Apte U; Sicinski P; Kaestner KH; Albrecht JH
    Proc Natl Acad Sci U S A; 2020 Jul; 117(29):17177-17186. PubMed ID: 32631996
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Suppression of Hepatocyte Nuclear Factor 4 α by Long-term Infection of Hepatitis B Virus Contributes to Tumor Cell Proliferation.
    Park S; Ha YN; Dezhbord M; Lee AR; Park ES; Park YK; Won J; Kim NY; Choo SY; Shin JJ; Ahn CH; Kim KH
    Int J Mol Sci; 2020 Jan; 21(3):. PubMed ID: 32023898
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protein arginine methyl transferase 1- and Jumonji C domain-containing protein 6-dependent arginine methylation regulate hepatocyte nuclear factor 4 alpha expression and hepatocyte proliferation in mice.
    Zhao J; Adams A; Roberts B; O'Neil M; Vittal A; Schmitt T; Kumer S; Cox J; Li Z; Weinman SA; Tikhanovich I
    Hepatology; 2018 Mar; 67(3):1109-1126. PubMed ID: 29023917
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis.
    Hayhurst GP; Lee YH; Lambert G; Ward JM; Gonzalez FJ
    Mol Cell Biol; 2001 Feb; 21(4):1393-403. PubMed ID: 11158324
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An HNF4α-microRNA-194/192 signaling axis maintains hepatic cell function.
    Morimoto A; Kannari M; Tsuchida Y; Sasaki S; Saito C; Matsuta T; Maeda T; Akiyama M; Nakamura T; Sakaguchi M; Nameki N; Gonzalez FJ; Inoue Y
    J Biol Chem; 2017 Jun; 292(25):10574-10585. PubMed ID: 28465351
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The stable repression of mesenchymal program is required for hepatocyte identity: a novel role for hepatocyte nuclear factor 4α.
    Santangelo L; Marchetti A; Cicchini C; Conigliaro A; Conti B; Mancone C; Bonzo JA; Gonzalez FJ; Alonzi T; Amicone L; Tripodi M
    Hepatology; 2011 Jun; 53(6):2063-74. PubMed ID: 21384409
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation.
    Walesky C; Gunewardena S; Terwilliger EF; Edwards G; Borude P; Apte U
    Am J Physiol Gastrointest Liver Physiol; 2013 Jan; 304(1):G26-37. PubMed ID: 23104559
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hepatocyte Nuclear Factor 4α Prevents the Steatosis-to-NASH Progression by Regulating p53 and Bile Acid Signaling (in mice).
    Xu Y; Zhu Y; Hu S; Xu Y; Stroup D; Pan X; Bawa FC; Chen S; Gopoju R; Yin L; Zhang Y
    Hepatology; 2021 Jun; 73(6):2251-2265. PubMed ID: 33098092
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Abrogating K458 acetylation enhances hepatocyte nuclear factor 4α (HNF4α)-induced differentiation therapy for hepatocellular carcinoma.
    Liu F; Peng Y; Qian H; Xiao MC; Ding CH; Zhang X; Xie WF
    J Dig Dis; 2024 Apr; 25(4):255-265. PubMed ID: 38837552
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene.
    Maeda Y; Hwang-Verslues WW; Wei G; Fukazawa T; Durbin ML; Owen LB; Liu X; Sladek FM
    Biochem J; 2006 Dec; 400(2):303-13. PubMed ID: 16895524
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of Hepatic Metabolic Functions by a Novel Variant of Hepatocyte Nuclear Factor 4γ.
    Sasaki S; Urabe M; Maeda T; Suzuki J; Irie R; Suzuki M; Tomaru Y; Sakaguchi M; Gonzalez FJ; Inoue Y
    Mol Cell Biol; 2018 Dec; 38(24):. PubMed ID: 30224520
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Apoptosis signal-regulating kinase 1 mediates the inhibitory effect of hepatocyte nuclear factor-4α on hepatocellular carcinoma.
    Jiang CF; Wen LZ; Yin C; Xu WP; Shi B; Zhang X; Xie WF
    Oncotarget; 2016 May; 7(19):27408-21. PubMed ID: 27050273
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crosstalk of hepatocyte nuclear factor 4a and glucocorticoid receptor in the regulation of lipid metabolism in mice fed a high-fat-high-sugar diet.
    Lu H; Lei X; Winkler R; John S; Kumar D; Li W; Alnouti Y
    Lipids Health Dis; 2022 May; 21(1):46. PubMed ID: 35614477
    [TBL] [Abstract][Full Text] [Related]  

  • 16. EPS15R, TASP1, and PRPF3 are novel disease candidate genes targeted by HNF4alpha splice variants in hepatocellular carcinomas.
    Niehof M; Borlak J
    Gastroenterology; 2008 Apr; 134(4):1191-202. PubMed ID: 18395097
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of Hepatocyte Nuclear Factor 4 Alpha in Liver Cancer.
    Kotulkar M; Paine-Cabrera D; Apte U
    Semin Liver Dis; 2024 Aug; 44(3):383-393. PubMed ID: 38901435
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CCAAT-enhancer binding protein-α (C/EBPα) and hepatocyte nuclear factor 4α (HNF4α) regulate expression of the human fructose-1,6-bisphosphatase 1 (FBP1) gene in human hepatocellular carcinoma HepG2 cells.
    Wattanavanitchakorn S; Rojvirat P; Chavalit T; MacDonald MJ; Jitrapakdee S
    PLoS One; 2018; 13(3):e0194252. PubMed ID: 29566023
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Yes-associated protein/TEA domain family member and hepatocyte nuclear factor 4-alpha (HNF4α) repress reciprocally to regulate hepatocarcinogenesis in rats and mice.
    Cai WY; Lin LY; Hao H; Zhang SM; Ma F; Hong XX; Zhang H; Liu QF; Ye GD; Sun GB; Liu YJ; Li SN; Xie YY; Cai JC; Li BA
    Hepatology; 2017 Apr; 65(4):1206-1221. PubMed ID: 27809333
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H.
    Luebke-Wheeler J; Zhang K; Battle M; Si-Tayeb K; Garrison W; Chhinder S; Li J; Kaufman RJ; Duncan SA
    Hepatology; 2008 Oct; 48(4):1242-50. PubMed ID: 18704925
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.